Shiro Miyoshi

Design, synthesis and SAR investigation of thienosultam derivatives as ADAMTS-5 (aggrecanase-2) inhibitors.

Masakazu Atobe, Eiichi Tanaka, Naomi Maekawara, 2013, Bioorganic & medicinal chemistry letters.

A series of thiazole derivatives bearing thiazolidin-4-one as non-competitive ADAMTS-5 (aggrecanase-2) inhibitors.

Masakazu Atobe, Eiichi Tanaka, N. Jinno, 2013, Bioorganic & medicinal chemistry letters.

Effects of sialic acid derivative on long circulation time and tumor concentration of liposomes

K. Higashi, Takashi Kato, H. Yamauchi, 1995 .

SAR-based optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as highly potent EP1 receptor antagonists.

Masakazu Atobe, Ken-ichi Kasahara, M. Kawanishi, 2013, Bioorganic & medicinal chemistry letters.

A Versatile Synthetic Method of 1-Alkylazulenes and Azulene by the iReactions of 3-Methoxycarbonyl-2H-cyclohepta(b)furan-2-one with in situ Generated Enamines.

K. Takase, Shiro Miyoshi, M. Yasunami, 1993 .

Hit-to-lead optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as a novel class of EP1 receptor antagonists.

Masakazu Atobe, Ken-ichi Kasahara, M. Kawanishi, 2013, Bioorganic & medicinal chemistry letters.

Discovery of 2-(1H-indazol-1-yl)-thiazole derivatives as selective EP(1) receptor antagonists for treatment of overactive bladder by core structure replacement.

Masakazu Atobe, Ken-ichi Kasahara, M. Kawanishi, 2014, Bioorganic & medicinal chemistry letters.

Discovery of a benzimidazole series of ADAMTS-5 (aggrecanase-2) inhibitors by scaffold hopping.

Masakazu Atobe, Eiichi Tanaka, M. Kawanishi, 2014, European journal of medicinal chemistry.