M. Tadin-Strapps

发表

Titrating haemophilia B phenotypes using siRNA strategy: evidence that antithrombotic activity is separated from bleeding liability

R. Bentley, K. Leander, L. Sepp-Lorenzino, 2015, Thrombosis and Haemostasis.

siRNA-mediated inhibition of SREBP cleavage-activating protein reduces dyslipidemia in spontaneously dysmetabolic rhesus monkeys.

Shirly Pinto, R. Mogg, D. McLaren, 2017, Metabolism: clinical and experimental.

Development of Lipoprotein(a) siRNAs for Mechanism of Action Studies in Non-Human Primate Models of Atherosclerosis

S. Bartz, D. Johns, S. Yendluri, 2015, Journal of Cardiovascular Translational Research.

TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation

Dawn M. Toolan, D. Stone, J. Disa, 2017, Proceedings of the National Academy of Sciences.

DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates.

Dermot F. Reilly, S. Bartz, D. Reilly, 2018, Cell metabolism.

Targeting of hepatic angiotensinogen using chemically modified siRNAs results in significant and sustained blood pressure lowering in a rat model of hypertension

S. Bartz, D. Cully, Marianne E. Eybye, 2014, Hypertension Research.

Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9[S]

S. Bartz, Kenny K. Wong, A. Sachs, 2011, Journal of Lipid Research.

Proof-of-concept Studies for siRNA-mediated Gene Silencing for Coagulation Factors in Rat and Rabbit

Marian E. Gindy, K. Leander, J. Disa, 2015, Molecular therapy. Nucleic acids.

Preclinical and translational evaluation of coagulation factor IXa as a novel therapeutic target

Manash S. Chatterjee, Kung-I Feng, J. Metzger, 2016, Pharmacology research & perspectives.

Attenuation of Slc27a5 gene expression followed by LC-MS measurement of bile acid reconjugation using metabolomics and a stable isotope tracer strategy.

S. Bartz, T. Hankemeier, Kenny K. Wong, 2011, Journal of proteome research.

ApoB siRNA-induced Liver Steatosis is Resistant to Clearance by the Loss of Fatty Acid Transport Protein 5 (Fatp5)

T. Hankemeier, L. Mitnaul, A. Sachs, 2011, Lipids.

Discovering metabolic disease gene interactions by correlated effects on cellular morphology

John G Doench, Dermot F. Reilly, J. Flannick, 2019, Molecular metabolism.

Alterations in the hepatic transcriptional landscape after RNAi mediated ApoB silencing in cynomolgus monkeys.

S. Bartz, S. Chia, A. V. van Gool, 2015, Atherosclerosis.

Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey[S]

S. Bartz, Shirly Pinto, D. McLaren, 2016, Journal of Lipid Research.

siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids[S]

S. Bartz, Kenny K. Wong, L. Mitnaul, 2011, Journal of Lipid Research.

Factor XII full and partial null in rat confers robust antithrombotic efficacy with no bleeding

R. Bentley, D. Seiffert, L. Hoos, 2015, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle Growth

B. Dogdas, J. Disa, L. Sepp-Lorenzino, 2016, Molecular therapy. Nucleic acids.

Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle Growth.

B. Dogdas, J. Disa, L. Sepp-Lorenzino, 2016 .

Factor XII full and partial null in rat confers robust antithrombotic efficacy with no bleeding

R. Bentley, D. Seiffert, L. Hoos, 2015, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.