J. Hickson

发表

The RTK inhibitor, ABT-869 alone or in combination with various cytotoxic therapies demonstrate significant tumor growth inhibition in orthotopic hepatocellular carcinoma, renal cell carcinoma and prostate xenografts

S. Davidsen, J. O'Connor, Baole Wang, 2007 .

Tumor-Host Interactions at the Metastatic Site: MKK4, Signal Transduction and the Stress Response

V. Robinson, C. Rinker-Schaeffer, Jonathan C. Berger, 2005 .

Inhibition of prostate cancer metastatic colonization by ∼4.2 Mb of human chromosome 12

E. Jaeger, C. Rinker-Schaeffer, M. Sokoloff, 2004 .

Comparative sclerochronology of modern and mid-Pliocene (c. 3.5 Ma) Aequipecten opercularis (Mollusca, Bivalvia): an insight into past and future climate change in the north-east Atlantic region

P. Balson, B. Schöne, T. Heaton, 2009 .

The shell of the Queen Scallop Aequipecten opercularis (L.) as a promising tool for palaeoenvironmental reconstruction: evidence and reasons for equilibrium stable-isotope incorporation

P. Balson, T. Heaton, Andrew L. A. Johnson, 1999 .

Climate records from a bivalved Methuselah (Arctica islandica, Mollusca; Iceland)

B. Schöne, W. Oschmann, J. Fiebig, 2005 .

Mitogen-activated Protein Kinase Kinase 4 ( MKK 4 ) Acts as a Metastasis Suppressor Gene in Human Ovarian Carcinoma 1

A. Montag, D. Huo, C. Rinker-Schaeffer, 2002 .

[18F]BTK-1: A Novel Positron Emission Tomography Tracer for Imaging Bruton’s Tyrosine Kinase

R. Comley, D. Wooten, K. Wilcox, 2022, Molecular Imaging and Biology.

Stopping cancer before it colonizes

C. Rinker-Schaeffer, J. Hickson, 2006, Nature Medicine.

The Queen Scallop Aequipecten opercularis: a new source of information on late Cenozoic marine environments in Europe

P. Balson, T. Heaton, S. Chenery, 2000, Geological Society, London, Special Publications.

Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma.

A. Montag, D. Huo, C. Rinker-Schaeffer, 2002, Cancer research.

Noninvasive molecular imaging of apoptosis in vivo using a modified firefly luciferase substrate, Z-DEVD-aminoluciferin

D. Klaubert, S. Ackler, J. Bouska, 2010, Cell Death and Differentiation.

New paradigms for the function of JNKK1/MKK4 in controlling growth of disseminated cancer cells.

C. Rinker-Schaeffer, S. Yamada, K. Macleod, 2008, Cancer letters.

Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7.

A. Lin, W. Stadler, C. Rinker-Schaeffer, 2005, Cancer research.

MKK4 and metastasis suppression: A marriage of signal transduction and metastasis research

V. Robinson, C. Rinker-Schaeffer, D. V. Vander Griend, 2004, Clinical & Experimental Metastasis.

The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma.

D. Huo, A. Lin, C. Rinker-Schaeffer, 2006, Cancer research.

c-Jun NH2-terminal kinase activating kinase 1/mitogen-activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation.

D. Huo, C. Rinker-Schaeffer, S. Yamada, 2008, Cancer research.

Societal interactions in ovarian cancer metastasis: a quorum-sensing hypothesis

B. Bassler, C. Rinker-Schaeffer, Carrie Rinker-Schaeffer, 2008, Clinical & Experimental Metastasis.

Using metastasis suppressor proteins to dissect interactions among cancer cells and their microenvironment

C. Rinker-Schaeffer, T. Lotan, Jennifer Taylor, 2008, Cancer and Metastasis Reviews.

LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody-Drug Conjugates.

K. Gish, T. Uziel, D. Chao, 2018, Cancer research.

The p 38 Kinases MKK 4 and MKK 6 Suppress Metastatic Colonization in Human Ovarian Carcinoma

D. Huo, A. Lin, C. Rinker-Schaeffer, 2006 .

Metastasis suppressor genes: From gene identification to protein function and regulation

V. Robinson, C. Rinker-Schaeffer, D. V. Vander Griend, 2005, Cancer biology & therapy.

Clearance of systemic hematologic tumors by venetoclax (Abt-199) and navitoclax

J. Leverson, Jun Chen, S. Tahir, 2015, Pharmacology research & perspectives.

In vitro metastatic colonization of human ovarian cancer cells to the omentum

G. Prins, C. Rinker-Schaeffer, T. Lotan, 2010, Clinical and Experimental Metastasis.

ABT-165, a Dual Variable Domain Immunoglobulin (DVD-Ig) Targeting DLL4 and VEGF, Demonstrates Superior Efficacy and Favorable Safety Profiles in Preclinical Models

L. Naumovski, S. Morgan-Lappe, E. DiGiammarino, 2018, Molecular Cancer Therapeutics.

In vivo optical imaging: preclinical applications and considerations.

J. Hickson, 2009, Urologic oncology.

The Volume of Three-Dimensional Cultures of Cancer Cells InVitro Influences Transcriptional Profile Differences and Similarities with Monolayer Cultures and Xenografted Tumors

Catarina Brito, Xin Lu, Kedar S Vaidya, 2017, Neoplasia.

FDG-PET as a pharmacodynamic biomarker for early assessment of treatment response to linifanib (ABT-869) in a non-small cell lung cancer xenograft model

M. Day, P. Tapang, D. Albert, 2012, Cancer Chemotherapy and Pharmacology.

Effects of Buprenorphine in a Preclinical Orthotopic Tumor Model of Ovarian Carcinoma in Female CB17 SCID Mice.

D. Frost, Natalie A. Bratcher, J. Hickson, 2019, Journal of the American Association for Laboratory Animal Science : JAALAS.

Abstract 953: LRRC15 is a novel antigen in sarcoma and the therapeutic target of the antibody-drug conjugate (ADC) ABBV-085

K. Gish, G. Demetri, Ying Huang, 2018, Experimental and Molecular Therapeutics.

Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo.

Mikkel A. Algire, Chaohong Sun, J. Randolph, 2023, Journal of medicinal chemistry.

PDGFR-α as a potential therapeutic target in uterine sarcomas

E. Lengyel, A. Montag, S. Yamada, 2007 .

Flexible peritoneal windows for quantitative fluorescence and bioluminescence preclinical imaging.

Chin-Tu Chen, C. Rinker-Schaeffer, J. Souris, 2013, Molecular imaging.

LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody-Drug Conjugates.

K. Gish, T. Uziel, D. Chao, 2018, Cancer research.

PDGFR-alpha as a potential therapeutic target in uterine sarcomas.

E. Lengyel, A. Montag, S. Yamada, 2007, Gynecologic oncology.

c-Jun NH2-terminal kinase activating kinase 1/mitogen-activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation.

D. Huo, C. Rinker-Schaeffer, S. Yamada, 2008, Cancer research.