R. Weinkam

发表

Application of chemical ionization mass spectrometry to the study of stereoselective in vitro metabolism of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane.

P. Callery, J. Gal, N. Castagnoli, 1976, Analytical chemistry.

Quantitative dose-response relations for the cytotoxic activity of chloroethylnitrosoureas in cell culture.

D. Deen, R. Weinkam, 1982, Cancer research.

The in vivo cytotoxic activity of procarbazine and procarbazine metabolites against L1210 ascites leukemia cells in CDF1 mice and the effects of pretreatment with procarbazine, phenobarbital, diphenylhydantoin, and methylprednisolone upon in vivo procarbazine activity

R. Weinkam, D. A. Shiba, 2004, Cancer Chemotherapy and Pharmacology.

Quantitative analysis of procarbazine, procarbazine metabolites and chemical degradation products with application to pharmacokinetic studies.

R. Weinkam, D. A. Shiba, 1982, Journal of chromatography.

The half-lives of alkylating intermediates from diethylnitrosamine and N-nitrosopyrrolidine: a method for the measurement of metabolically generated reactive species.

R. Weinkam, T. H. Keenan, 1985, Toxicology and applied pharmacology.

Pharmacokinetics of BCNU in man: a preliminary study of 20 patients.

V. Levin, R. Weinkam, W. Hoffman, 1978, Cancer treatment reports.

Competitive reactions of protonated polyamines in the gas phase.

R. Weinkam, 1978, Biomedical mass spectrometry.

Hydrolysis, methanolysis and ammonolysis of dicarboxylic acids and methyl esters under conditions of chemical ionization mass spectrometry

J. Gal, R. Weinkam, 1976 .

Quantitation of lipophilic chloroethylnitrosourea cancer chemotherapeutic agents.

T. Liu, R. Weinkam, T. Liu, 1982, Journal of pharmaceutical sciences.

Protein mediated chemical reactions of chloroethylnitrosoureas.

T. Liu, H. S. Lin, R. Weinkam, 1980, Chemico-biological interactions.

Lipophilic drugs and lipoproteins: partitioning effects on chloroethylnitrosourea reaction rates in serum.

J. Kane, V. Levin, A. Finn, 1980, The Journal of pharmacology and experimental therapeutics.

Reactions of 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in aqueous solution.

H. S. Lin, R. Weinkam, 1979, Journal of medicinal chemistry.

The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the plasma pharmacokinetics and biotransformation of BCNU

V. Levin, J. Stearns, A. Finn, 1979, The Journal of pharmacology and experimental therapeutics.

Analysis for 1,3-bis(2-chloroethyl)-1-nitrosourea by chemical ionization mass spectrometry.

D. Furst, V. Levin, R. Weinkam, 1978, Clinical chemistry.

Rotamer stability of histidine and histidine derivatives.

E. C. Jorgensen, R. Weinkam, 1973, Journal of the American Chemical Society.

Angiotensin II analogs. IX. Conformational studies of angiotensin II by proton magnetic resonance.

E. C. Jorgensen, R. Weinkam, 1971, Journal of the American Chemical Society.

Synthesis of cis- and trans-1-(3,4-dimethoxybenzyl)-3,7-dimethyl-5,8-dimethoxy-1,2,3,4-tetrahydroxyisoquinoline. Mechanism of the Bischler-Napieralski reaction

J. Gal, N. Castagnoli, R. Weinkam, 1974 .

Formation of nitrosamines by alkylation of diazotates

C. S. Cooper, R. Weinkam, A. Peyton, 1983 .

Metabolism of 1,3-bis(2-chloroethyl)-1-nitrosourea by rat hepatic microsomes.

H. S. Lin, R. Weinkam, 1981, Journal of medicinal chemistry.

Free radical analogs of histidine.

E. C. Jorgensen, R. Weinkam, 1971, Journal of the American Chemical Society.

Effects of four penetration enhancers on corneal permeability of drugs in vitro.

D. Tang-Liu, R. Weinkam, H. Takruri, 1994, Journal of pharmaceutical sciences.

A method for measuring the lifetime of chemically and metabolically generated electrophilic species.

R. Weinkam, T. H. Keenan, 1983, Chemico-biological interactions.

Metabolic activation of procarbazine.

R. Weinkam, D. A. Shiba, 1978, Life sciences.

Chloroethylnitrosourea cancer chemotherapeutic agents.

H. S. Lin, R. Weinkam, 1982, Advances in pharmacology and chemotherapy.

Effects of bifunctional interactions in the chemical ionization mass spectrometry of carboxylic acids and methyl esters

J. Gal, R. Weinkam, 1976 .

Reactions of protonated diamino acids in the gas phase

R. Weinkam, 1978 .

Importance of intramolecular associations in the chemical ionization mass spectra of monoenoic and monoepoxy fatty acid methyl esters

R. Weinkam, 1974 .

Relatively Simple Modification of an AEI MS-902 High-Resolution Mass Spectrometer to Permit Chemical Ionization Studies

W. Trager, W. Garland, R. Weinkam, 1974 .

Direct reaction mixture analysis by probe insertion chemical ionization mass spectrometry

R. Weinkam, Huey‐shin Lin, 1979 .

Chemical ionization mass spectrometric measurement of α-methyldopa and s-dopa metabolites in rat brain regions

K. Melmon, C. Freed, N. Castagnoli, 1977 .

HPLC Quantitation of Levobunolol and Its Metabolite, Dihydrolevobunolol in Biological Fluids

D. Tang-Liu, R. Weinkam, S. Liu, 1986 .

Chemical Ionization Techniques for the Analysis of Labile Compounds: 1,3-bis-(2-chloroethyl)-1-nitrosourea Plasma Clearance and Degradation

V. Levin, J. Stearns, H. S. Lin, 1978 .

Determination of phenylbutazone, tolbutamide and metabolites in plasma and urine using chemical ionization mass spectrometry.

P. Meffin, M. Rowland, R. Weinkam, 1977, Biomedical mass spectrometry.

Comparative pharmacokinetics of 1-(2-chloroethyl)-3-(2,6-dioxo-1-piperidyl)-1-nitrosourea in rats and patients and extrapolation to clinical trials.

V. Levin, R. Weinkam, J. Liu, 1981, Cancer research.

Accurate mass measurement at low resolving power with mass spectrometer-computer systems

R. Weinkam, J. D'Angona, 1979 .

Angiotensin II analogs. 8. The use of free radical containing peptides to indicate the conformation of the carboxyl terminal region of angiotensin II.

E. C. Jorgensen, R. Weinkam, 1971, Journal of the American Chemical Society.

Regioselective synthesis of unsymmetrical deuterium labelled hydrazines and azoxy compounds

C. S. Cooper, R. Weinkam, 1984 .

Ocular and systemic bioavailability of ophthalmic flurbiprofen

D. Tang-Liu, R. Weinkam, S. Liu, 1984, Journal of Pharmacokinetics and Biopharmaceutics.

QuantitativeDose-ResponseRelationsfor the CytotoxicActivityof Chloroethylnitrosoureasin Cell Culture

D. Deen, R. Weinkam, 2006 .

Intracellular activation of cytotoxic agents: kinetic models for methylnitrosoureas and N-methyl-N'-nitro-N-nitrosoguanidine in cell culture.

M. Dolan, R. Weinkam, 1989, Chemical research in toxicology.

Application of chemical ionization mass spectrometry and stable isotopes in studies of α-methyldopa metabolism

K. Melmon, M. Ames, C. Freed, 1978 .

A kinetic model of the cell culture cytotoxicity of metabolically activated agents: N-methyl-N-(acetoxymethyl)nitrosamine, methylnitrosourethane, and (methylazoxy)methanol acetate.

R. Weinkam, I. Plakunov, 1989, Chemical research in toxicology.