J. Hirosumi

发表

Ameliorating effect of FK614, a novel nonthiazolidinedione peroxisome proliferator-activated receptor gamma agonist, on insulin resistance in Zucker fatty rat.

I. Kawamura, M. Ita, J. Seki, 2005, European journal of pharmacology.

The Sodium Glucose Cotransporter 2 Inhibitor Ipragliflozin Promotes Preferential Loss of Fat Mass in Non-obese Diabetic Goto-Kakizaki Rats.

H. Minoura, S. Takakura, T. Takasu, 2017, Biological & pharmaceutical bulletin.

Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance.

M. Karin, Lufen Chang, G. Hotamisligil, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Exclusive Action of Transmembrane TNFα in Adipose Tissue Leads to Reduced Adipose Mass and Local But Not Systemic Insulin Resistance.

Haiyan Xu, K. Uysal, G. Hotamisligil, 2002, Endocrinology.

FR177391, A New Anti-hyperlipidemic Agent from Serratia

I. Kawamura, S. Tsujimoto, M. Inami, 2005, The Journal of Antibiotics.

FK143, a novel nonsteroidal inhibitor of steroid 5α-reductase: (2) In vivo effects on rat and dog prostates

M. Okuhara, Y. Notsu, H. Kojo, 1995, The Journal of Steroid Biochemistry and Molecular Biology.

FK143, a novel nonsteroidal inhibitor of steroid 5α-reductase: (1) In vitro effects on human and animal prostatic enzymes

M. Okuhara, Y. Notsu, H. Kojo, 1995, The Journal of Steroid Biochemistry and Molecular Biology.

Exclusive action of transmembrane TNF alpha in adipose tissue leads to reduced adipose mass and local but not systemic insulin resistance.

Haiyan Xu, K. Uysal, G. Hotamisligil, 2002, Endocrinology.

Pharmacological characterization of a novel, orally active, nonpeptide bradykinin B2 receptor antagonist, FR167344.

K. Nakahara, T. Inoue, H. Kayakiri, 1997, European journal of pharmacology.

Phosphodiesterase type 5 inhibition ameliorates nephrotoxicity induced by cyclosporin A in spontaneous hypertensive rats.

K. Hamada, S. Mutoh, N. Hosogai, 2003, European journal of pharmacology.

Effects of growth factors on cytosolic free calcium concentration and DNA synthesis in cultured rat aortic smooth muscle cells.

Y. Ouchi, H. Orimo, M. Watanabe, 1989, The Tohoku journal of experimental medicine.

Effects of a nonpeptide bradykinin B2 receptor antagonist, FR167344, on different in vivo animal models of inflammation

K. Nakahara, N. Inamura, C. Hatori, 1997, British journal of pharmacology.

Inflammatory responses in cuff-induced atherosclerosis in rabbits.

S. Mutoh, Y. Ohkubo, A. Nomoto, 1987, Atherosclerosis.

FRM146687, a novel steroid 5α‐reductase inhibitor: In vitro and in vivo effects on prostates

Y. Notsu, H. Kojo, J. Hirosumi, 1997 .

A central role for JNK in obesity and insulin resistance

Michael Karin, M. Karin, Lufen Chang, 2002, Nature.

Choleretic Actions of Insulin-Like Growth Factor-I, Prednisolone, and Ursodeoxycholic Acid in Rats

I. Kawamura, S. Takakura, S. Mutoh, 2003, Digestive Diseases and Sciences.

Insulin-like growth factor-I enhances choleretic action of FK506 in rats.

I. Kawamura, S. Takakura, S. Mutoh, 2003, Transplantation proceedings.

Novel steroid 5 alpha-reductase inhibitor FK143: its dual inhibition against the two isozymes and its effect on transcription of the isozyme genes.

M. Okuhara, Y. Notsu, H. Kojo, 1995, Molecular pharmacology.

Alteration in expression profiles of a series of diabetes-related genes in db/db mice following treatment with thiazolidinediones.

Y. Notsu, H. Kojo, Y Notsu, 2000, Japanese journal of pharmacology.

Inhibitory effect of transforming growth factor-beta on epidermal growth factor-induced proliferation of cultured rat aortic smooth muscle cells.

Y. Ouchi, H. Orimo, M. Watanabe, 1988, Biochemical and biophysical research communications.

Purification and initial characterization of a protein which facilitates assembly of nucleosome-like structure from mammalian cells.

K. Sugasawa, F. Hanaoka, Y. Ishimi, 1984, European journal of biochemistry.

A protein which facilitates assembly of nucleosome-like structures in vitro in mammalian cells.

H. Yasuda, F. Hanaoka, Y. Ishimi, 1983, Journal of biochemistry.

1,25(OH)2D3 increases cytosolic Ca++ concentration of osteoblastic cells, clone MC3T3-E1.

H. Orimo, M. Watanabe, J. Hirosumi, 1987, Biochemical and biophysical research communications.

Antiatherogenic activity of FR34235 (Nilvadipine), a new potent calcium antagonist. Effect on cuff-induced intimal thickening of rabbit carotid artery.

S. Mutoh, A. Nomoto, I. Yamaguchi, 1987, Atherosclerosis.

Effect of Nifedipine on DNA Synthesis and Cytosolic Free Calcium Concentration Stimulated by Growth Factors: A Study Using Cultured Rat Aortic Smooth-Muscle Cells

Y. Ouchi, H. Orimo, J. Kusunoki, 1989 .

Effect of superoxide and lipid peroxide on cytosolic free calcium concentration in cultured pig aortic endothelial cells.

Y. Ouchi, H. Orimo, M. Watanabe, 1988, Biochemical and biophysical research communications.

Pharmacological characteristics of a novel nonthiazolidinedione insulin sensitizer, FK614.

I. Kawamura, H. Kojo, M. Ita, 2004, European journal of pharmacology.

Mechanism by which a novel non‐thiazolidinedione peroxisome proliferator‐activated receptor γ agonist, FK614, ameliorates insulin resistance in Zucker fatty rats

I. Kawamura, H Minoura, S Takeshita, 2007, Diabetes, obesity & metabolism.

Asymmetric Oxidation of Sulphide on Metal Ion Planted in Mesoporous MCM-41

M. Iwamoto, Yasuhiro Tanaka, J. Hirosumi, 2001 .

Enantioselective oxidation of sulfide to sulfoxide on Ti-containing mesoporous silica prepared by a template-ion exchange method

S. Triwahyono, M. Iwamoto, Yasuhiro Tanaka, 2001 .