Junqin Chen

发表

Intracellular Shuttling and Mitochondrial Function of Thioredoxin-interacting Protein*

A. Shalev, G. Saxena, Junqin Chen, 2009, The Journal of Biological Chemistry.

JUMONJI, a Critical Factor for Cardiac Development, Functions as a Transcriptional Repressor*

Youngsook Lee, Tae-gyun Kim, Junqin Chen, 2003, Journal of Biological Chemistry.

Calcium Channel Blockers Act through Nuclear Factor Y to Control Transcription of Key Cardiac Genes

A. Shalev, J. Chatham, M. Young, 2012, Molecular Pharmacology.

Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes

P. Sethupathy, W. Qian, V. Petyuk, 2022, Nature communications.

Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein.

A. Shalev, H. Cha-Molstad, A. Szabó, 2009, American journal of physiology. Endocrinology and metabolism.

Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action.

P. Sethupathy, A. Shalev, Jason K. Kim, 2020, Cell metabolism.

Thioredoxin-interacting protein stimulates its own expression via a positive feedback loop.

A. Shalev, Junqin Chen, Guanlan Xu, 2014, Molecular endocrinology.

Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid–Induced ER Stress–Mediated β-Cell Death

G. Fontés, V. Poitout, A. Shalev, 2009, Diabetes.

Lack of TXNIP protects against mitochondria-mediated apoptosis , but not against fatty acid-induced , ER-stress-mediated beta cell death Running title : Lipotoxicity and TXNIP

G. Fontés, V. Poitout, A. Shalev, 2009 .

Thioredoxin‐interacting protein deficiency induces Akt/Bcl‐xL signaling and pancreatic beta‐cell mass and protects against diabetes

Roger A. Davis, A. Attie, A. Lusis, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Preventing β-Cell Loss and Diabetes With Calcium Channel Blockers

A. Shalev, Junqin Chen, Guanlan Xu, 2012, Diabetes.

Thioredoxin-Interacting Protein

A. Lusis, I. Mungrue, A. Shalev, 2008, Diabetes.

THIOREDOXIN-INTERACTING PROTEIN: A CRITICAL LINK BETWEEN GLUCOSE TOXICITY AND BETA CELL APOPTOSIS

A. Lusis, I. Mungrue, A. Shalev, 2007 .

FOXO1 COMPETES WITH CHREBP AND INHIBITS TXNIP TRANSCRIPTION IN PANCREATIC BETA CELLS

Carly R. Kibbe, A. Shalev, Junqin Chen, 2013 .

miR-204 Targets PERK and Regulates UPR Signaling and β-Cell Apoptosis.

A. Shalev, T. Grayson, Junqin Chen, 2016, Molecular endocrinology.

Islet ChREBP-β is increased in diabetes and controls ChREBP-α and glucose-induced gene expression via a negative feedback loop

A. Shalev, Junqin Chen, Guanlan Xu, 2016, Molecular metabolism.

miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function

A. Shalev, T. Grayson, Seongho Jo, 2017, Diabetes.

TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling.

L. Dell’Italia, D. Crossman, A. Shalev, 2016, American journal of physiology. Heart and circulatory physiology.

Thioredoxin-interacting Protein Promotes Islet Amyloid Polypeptide Expression through miR-124a and FoxA2*

A. Shalev, C. Verchere, C. Westwell-Roper, 2014, The Journal of Biological Chemistry.

1 THIOREDOXIN-INTERACTING PROTEIN PROMOTES ISLET AMYLOID POLYPEPTIDE EXPRESSION THROUGH MIR-124 A AND FOXA 2

A. Shalev, C. Verchere, C. Westwell-Roper, 2014 .

Thioredoxin-interacting protein regulates insulin transcription through microRNA-204

A. Shalev, Junqin Chen, Guanlan Xu, 2013, Nature Medicine.

Human glucagon expression is under the control of miR-320a.

A. Shalev, Seongho Jo, Junqin Chen, 2020, Endocrinology.

Jumonji Represses Atrial Natriuretic Factor Gene Expression by Inhibiting Transcriptional Activities of Cardiac Transcription Factors

Youngsook Lee, J. Sadoshima, Tae-gyun Kim, 2004, Molecular and Cellular Biology.

Exenatide inhibits beta-cell apoptosis by decreasing thioredoxin-interacting protein.

A. Shalev, Francesca M Couto, A. Minn, 2006, Biochemical and biophysical research communications.

Serum miR-204 is an early biomarker of type 1 diabetes-associated pancreatic beta-cell loss.

S. L. Bridges, F. Ovalle, A. Shalev, 2019, American journal of physiology. Endocrinology and metabolism.

Glucose-stimulated Expression of Txnip Is Mediated by Carbohydrate Response Element-binding Protein, p300, and Histone H4 Acetylation in Pancreatic Beta Cells*

A. Shalev, G. Saxena, H. Cha-Molstad, 2009, The Journal of Biological Chemistry.

FOXO1 Competes with Carbohydrate Response Element-binding Protein (ChREBP) and Inhibits Thioredoxin-interacting Protein (TXNIP) Transcription in Pancreatic Beta Cells*

Carly R. Kibbe, A. Shalev, Junqin Chen, 2013, The Journal of Biological Chemistry.

Generation of a conditional null allele of jumonji

P. Powers, Youngsook Lee, M. Mysliwiec, 2006, Genesis.

MicroRNA-200 Is Induced by Thioredoxin-interacting Protein and Regulates Zeb1 Protein Signaling and Beta Cell Apoptosis*

A. Shalev, Kyunghee Hong, Junqin Chen, 2014, The Journal of Biological Chemistry.

Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes

P. Sethupathy, W. Qian, V. Petyuk, 2022, Nature Communications.

Thioredoxin-Interacting Protein : A Critical Link Between Glucose Toxicity and β-Cell Apoptosis. Commentary

A. Lusis, I. Mungrue, J. Corbett, 2008 .

Deletion of Gdf15 reduces ER stress-induced beta cell apoptosis and diabetes.

A. Shalev, T. Grayson, Se-Jin Lee, 2022, Endocrinology.

Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein.

A. Shalev, H. Cha-Molstad, A. Szabó, 2009, American journal of physiology. Endocrinology and metabolism.

Mir-128 Targets Thioredoxin-Interacting Protein 3’UTR and Downregulates Its Expression in Pancreatic Beta Cells

A. Shalev, Junqin Chen, Guanlan Xu, 2018, Diabetes.