K. P. Tamm

发表

Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment

R. Nilsson, D. Grandér, J. Lehtiö, 2018, Cell Death & Disease.

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy

P. Pandolfi, B. Zhivotovsky, J. Lundin, 2009, Cell Death and Differentiation.

Erratum: Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy (Cell Death and Differentiation (2009) vol. 16 (1018-1029) 10.1038/cdd.20089.46)

B. Zhivotovsky, J. Lundin, Keisuke Ito, 2009 .

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy

B. Zhivotovsky, J. Lundin, M. Corcoran, 2009, Cell Death and Differentiation.

Interferon α Induces Nucleus-independent Apoptosis by Activating Extracellular Signal-regulated Kinase 1/2 and c-Jun NH2-Terminal Kinase Downstream of Phosphatidylinositol 3-Kinase and Mammalian Target of Rapamycin

B. Joseph, D. Grandér, T. Panaretakis, 2008 .

Interferon (cid:1) Induces Nucleus-independent Apoptosis by Activating Extracellular Signal-regulated Kinase 1/2 and c-Jun NH 2 -Terminal Kinase Downstream of Phosphatidylinositol 3-Kinase and Mammalian Target of Rapamycin

B. Joseph, D. Grandér, T. Panaretakis, 2007 .

Proteogenomic analysis of acute myeloid leukemia associates relapsed disease with reprogrammed energy metabolism both in adults and children

Husen M. Umer, C. Lindskog, L. Cavelier, 2022, Leukemia.

Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines

O. Kallioniemi, R. Jafari, J. Lehtiö, 2022, Nature Communications.

Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies

S. Lehmann, D. Grandér, T. Helleday, 2017, Nature Medicine.

Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets.

J. Komorowski, L. Cavelier, M. Höglund, 2021, Blood advances.

Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death

D. Grandér, Elias S. J. Arnér, I. Kolosenko, 2020, Science Advances.

Activation of STAT1 is required for interferon-alpha-mediated cell death.

D. Grandér, I. Kolosenko, V. Arulampalam, 2011, Experimental cell research.

An activated JAK/STAT3 pathway and CD45 expression are associated with sensitivity to Hsp90 inhibitors in multiple myeloma.

D. Grandér, I. Kolosenko, A. Österborg, 2013, Experimental cell research.

Title: PTENP1-AS contributes to BRAF inhibitor resistance and is associated with adverse clinical outcome in stage III melanoma

S. Kauppinen, H. Olsson, C. Ingvar, 2020 .

Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment

R. Nilsson, D. Grandér, J. Lehtiö, 2018, Cell Death & Disease.

Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs

G. Stark, P. Johnsson, D. Grandér, 2015, International journal of cancer.

Patients with activated B-cell like diffuse large B-cell lymphoma in high and low infectious disease areas have different inflammatory gene signatures

A. Kwiecińska, J. Lundahl, A. Bahnassy, 2013, Leukemia & lymphoma.

Mutational patterns and clonal evolution from diagnosis to relapse in pediatric acute lymphoblastic leukemia

M. Ringnér, A. Syvänen, M. Heyman, 2021, Scientific Reports.

Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies

A. Porwit, S. Lehmann, D. Grandér, 2013, Leukemia & lymphoma.

Identification of novel small molecules that inhibit STAT3-dependent transcription and function

D. Grandér, T. Helleday, I. Kolosenko, 2017, PloS one.

Abstract 2116: VPS34 inhibitor SB02024 activates cGAS-STING signaling and sensitizes tumors to STING agonist

A. Alexeyenko, B. Janji, S. Parpal, 2022, Cancer Research.

IL-6 activated JAK/STAT3 pathway and sensitivity to Hsp90 inhibitors in multiple myeloma.

D. Grandér, I. Kolosenko, K. P. Tamm, 2014, Current medicinal chemistry.

Glucocorticoid-induced cell death is mediated through reduced glucose metabolism in lymphoid leukemia cells

S. Stone-Elander, A. Porwit, D. Grandér, 2011, Blood cancer journal.

STAT3 is activated in multicellular spheroids of colon carcinoma cells and mediates expression of IRF9 and interferon stimulated genes

J. Serviss, I. Kolosenko, A. De Milito, 2019, Scientific Reports.

PTENP1-AS contributes to BRAF inhibitor resistance and is associated with adverse clinical outcome in stage III melanoma

S. Kauppinen, H. Olsson, C. Ingvar, 2020, bioRxiv.

Interferon alpha induces nucleus-independent apoptosis by activating extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase downstream of phosphatidylinositol 3-kinase and mammalian target of rapamycin.

B. Joseph, D. Grandér, T. Panaretakis, 2008, Molecular biology of the cell.