J. Alfón

发表

The New Antitumor Drug ABTL0812 Inhibits the Akt/mTORC1 Axis by Upregulating Tribbles-3 Pseudokinase

P. Bragado, Jordi Espadaler Mazo, G. Velasco, 2015, Clinical Cancer Research.

Pharmacodynamics of Phenobarbital Anesthesia and Pentylenetetrazol-Induced Maximal Seizures in a Rat Model of Neoplastic Spinal Cord Compression

A. Hoffman, T. Siegal, T. Siegal, 1994, Pharmaceutical Research.

UR-60427, a novel H4 receptor-inverse agonist that shows good efficacy in a rat asthma model

J. Cortijo, M. Merlos, D. Balsa, 2010, Inflammation Research.

The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells

J. Bosch-Barrera, G. Velasco, J. Lizcano, 2020, Autophagy.

A small molecule, orally active, α4β1/α4β7 dual antagonist reduces leukocyte infiltration and airway hyper‐responsiveness in an experimental model of allergic asthma in Brown Norway rats

J. Cortijo, J. Montesinos, M. Sanz, 2006 .

Alternative binding assay of GP IIb/IIIa antagonists with a nonradioactive labeling method of platelets.

M. Merlos, J. Alfón, A. Fernández de Arriba, 2001, Thrombosis research.

ABTL0812 enhances antitumor effect of paclitaxel and reverts chemoresistance in triple‐negative breast cancer models

J. Lizcano, M. Yeste-Velasco, T. Puig, 2022, Cancer communications.

Synthesis and Structure−Activity Relationship of a New Series of COX-2 Selective Inhibitors: 1,5-Diarylimidazoles

Carmen Almansa, Robert Soliva, R. Soliva, 2003 .

Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models

M. Yeste-Velasco, G. Gravina, C. Festuccia, 2022, Frontiers in Oncology.

A first-in-human phase I/Ib dose-escalation clinical trial of the autophagy inducer ABTL0812 in patients with advanced solid tumours.

H. Colom, P. Gascón, J. Lizcano, 2021, European journal of cancer.

The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis

J. Lizcano, M. Segura, M. Yeste-Velasco, 2020, Cell Death & Disease.

Therapeutic potential of the new TRIB3-mediated cell autophagy anticancer drug ABTL0812 in endometrial cancer.

C. Moiola, N. Eritja, X. Matías-Guiu, 2019, Gynecologic oncology.

The Effect of Immunosuppression by Total-Body Irradiation on the Pharmacodynamics of Centrally Active Drugs in Rats

A. Hoffman, R. Gorodetsky, J. Alfón, 1994, Pharmaceutical Research.

High-Dose Methotrexate Does Not Affect the Pharmacodynamics of Phenobarbital Hypnotic Action but Decreases the Central Nervous System (CNS) Sensitivity to Pentylenetetrazol-Induced Maximal Seizures in Rats

A. Hoffman, J. Alfón, 1992, Pharmaceutical Research.

The novel proautophagy anticancer drug ABTL0812 potentiates chemotherapy in adenocarcinoma and squamous nonsmall cell lung cancer

P. Gascón, M. Mancino, P. Bragado, 2020, International journal of cancer.

HMG-CoA reductase inhibitors reduce vascular monocyte chemotactic protein-1 expression in early lesions from hypercholesterolemic swine independently of their effect on plasma cholesterol levels.

L. Badimón, J. Martínez-González, M. Berrozpe, 2001, Atherosclerosis.

Platelet deposition on eroded vessel walls at a stenotic shear rate is inhibited by lipid-lowering treatment with atorvastatin.

L. Badimón, L Badimon, T. Royo, 1999, Arteriosclerosis, thrombosis, and vascular biology.

The New Antitumor Drug ABTL0812 Inhibits the Akt/mTORC1 Axis by Upregulating Tribbles-3 Pseudokinase

P. Bragado, Jordi Espadaler Mazo, G. Velasco, 2015, Clinical Cancer Research.