R. Kunita

发表

Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1H46R-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking

Y. Itoyama, S. Hadano, J. Ikeda, 2010, PloS one.

Defective relocalization of ALS2/alsin missense mutants to Rac1‐induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation

S. Hadano, J. Ikeda, A. Otomo, 2011, FEBS letters.

Z and W chromosomes of chickens: studies on their gene functions in sex determination and sex differentiation

T. Hori, M. Harata, S. Mizuno, 2003, Cytogenetic and Genome Research.

Molecular cloning of acid alpha-glucosidase cDNA of Japanese quail (Coturnix coturnix japonica) and the lack of its mRNA in acid maltase deficient quails.

Yuan-Tsong Chen, Jer-Yuarn Wu, J. Wu, 1997, Biochimica et biophysica acta.

Genetic background and gender effects on gross phenotypes in congenic lines of ALS2/alsin-deficient mice

S. Hadano, J. Ikeda, Y. Iwakura, 2010, Neuroscience Research.

Identification and characterization of novel members of the CREG family, putative secreted glycoproteins expressed specifically in brain.

J. Ikeda, A. Otomo, R. Kunita, 2002, Genomics.

A Single Base-Pair Deletion in Exon 7 in qgaa 1 Gene Responsible for Acid Maltase Deficiency in Japanese Quail ( Coturnix Coturnix Japonica )

Rieko Setsuie, T. Kikuchi, M. Sekine, 2005 .

ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics.

Shuh Narumiya, Takeharu Nishimoto, Asako Otomo, 2003, Human molecular genetics.

Identification and localization of two genes on the chicken Z chromosome: implication of evolutionary conservation of the Z chromosome among avian species

T. Hori, Y. Saitoh, S. Mizuno, 1993, Chromosome Research.

Molecular and cellular function of ALS2/alsin: Implication of membrane dynamics in neuronal development and degeneration

Asako Otomo, S. Hadano, J. Ikeda, 2007, Neurochemistry International.

Homo-oligomerization of ALS2 through Its Unique Carboxyl-terminal Regions Is Essential for the ALS2-associated Rab5 Guanine Nucleotide Exchange Activity and Its Regulatory Function on Endosome Trafficking*

Asako Otomo, S. Hadano, J. Ikeda, 2004, Journal of Biological Chemistry.

Predominant expression of a Z-chromosome-linked immunoglobulin superfamily gene, ZOV3, in steroidogenic cells of ovarian follicles and in embryonic gonads of chickens.

S. Mizuno, T. Kikuchi, R. Kunita, 1997, Differentiation; research in biological diversity.

The Rab5 Activator ALS2/alsin Acts as a Novel Rac1 Effector through Rac1-activated Endocytosis*

S. Hadano, J. Ikeda, A. Otomo, 2007, Journal of Biological Chemistry.

ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics.

S. Hadano, J. Ikeda, H. Osuga, 2007, Biochemical and biophysical research communications.

ALS2CL, the novel protein highly homologous to the carboxy‐terminal half of ALS2, binds to Rab5 and modulates endosome dynamics

S. Hadano, J. Ikeda, Y. Yanagisawa, 2004, FEBS letters.

Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking.

Robert H. Brown, S. Hadano, J. Shefner, 2006, Human molecular genetics.

ALS2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth.

S. Hadano, J. Ikeda, H. Osuga, 2008, Biochemical and biophysical research communications.