K. Suzuki-Utsunomiya

发表

Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1H46R-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking

Y. Itoyama, S. Hadano, J. Ikeda, 2010, PloS one.

Defective relocalization of ALS2/alsin missense mutants to Rac1‐induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation

S. Hadano, J. Ikeda, A. Otomo, 2011, FEBS letters.

Altered oligomeric states in pathogenic ALS2 variants associated with juvenile motor neuron diseases cause loss of ALS2-mediated endosomal function

H. Shang, S. Hadano, S. Nakagawa, 2018, The Journal of Biological Chemistry.

Sepsis-Induced Hypercytokinemia and Lymphocyte Apoptosis in Aging-Accelerated Klotho Knockout Mice

T. Chiba, K. Hozumi, T. Yahata, 2013, Shock.

Genetic background and gender effects on gross phenotypes in congenic lines of ALS2/alsin-deficient mice

S. Hadano, J. Ikeda, Y. Iwakura, 2010, Neuroscience Research.

Fermentation of non-sterilized fish biomass with a mixed culture of film-forming yeasts and lactobacilli and its effect on innate and adaptive immunity in mice.

S. Inoue, A. Kamijo, K. Suzuki-Utsunomiya, 2013, Journal of bioscience and bioengineering.

Molecular and cellular function of ALS2/alsin: Implication of membrane dynamics in neuronal development and degeneration

Asako Otomo, S. Hadano, J. Ikeda, 2007, Neurochemistry International.

Persistent inflammation and T cell exhaustion in severe sepsis in the elderly

K. Hozumi, S. Inoue, S. Inokuchi, 2014, Critical Care.

Reduction of Immunocompetent T Cells Followed by Prolonged Lymphopenia in Severe Sepsis in the Elderly*

T. Chiba, S. Inoue, S. Morita, 2013, Critical care medicine.

The Rab5 Activator ALS2/alsin Acts as a Novel Rac1 Effector through Rac1-activated Endocytosis*

S. Hadano, J. Ikeda, A. Otomo, 2007, Journal of Biological Chemistry.

ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics.

S. Hadano, J. Ikeda, H. Osuga, 2007, Biochemical and biophysical research communications.

ALS2CL, the novel protein highly homologous to the carboxy‐terminal half of ALS2, binds to Rab5 and modulates endosome dynamics

S. Hadano, J. Ikeda, Y. Yanagisawa, 2004, FEBS letters.

Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking.

Robert H. Brown, S. Hadano, J. Shefner, 2006, Human molecular genetics.

ALS2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth.

S. Hadano, J. Ikeda, H. Osuga, 2008, Biochemical and biophysical research communications.

Impaired innate and adaptive immunity of accelerated-aged Klotho mice in sepsis

T. Chiba, K. Hozumi, S. Inoue, 2012, Critical Care.

Central nervous system specific high molecular weight ALS2/alsin homophilic complex is enriched in mouse brain synaptosomes.

S. Hadano, Shun Mitsui, A. Otomo, 2022, Biochemical and biophysical research communications.