G. S. Hamilton

发表

The small molecule FKBP ligand GPI 1046 induces partial striatal re-innervation after intranigral 6-hydroxydopamine lesion in rats

J. Steiner, D. Ross, Hongzhi Guo, 2001, Neuroscience Letters.

Effects of Neuroimmunophilin Ligands on Parkinson’s Disease and Cognition

J. Steiner, T. Morrow, H. Sauer, 2003 .

Systemic treatment with GPI 1046 improves spatial memory and reverses cholinergic neuron atrophy in the medial septal nucleus of aged mice

J. Steiner, H. Sauer, Hong Jiang, 1999, Brain Research.

Neuroimmunophilin Ligands Stimulate Recovery of Injured Sciatic Nerves

H. Valentine, J. Steiner, T. Morrow, 2003 .

Immunophilin ligands for the treatment of neurological disorders

G. S. Hamilton, 1998 .

Immunophilins: beyond immunosuppression.

J. Steiner, G. S. Hamilton, 1998, Journal of medicinal chemistry.

SYNTHESIS AND GLUTAMATE ANTAGONIST ACTIVITY OF 4-PHOSPHONOALKYLQUINOLINE DERIVATIVES : A NOVEL CLASS OF NON-NMDA ANTAGONIST

J. Ferkany, D. L. Bednar, E. Karbon, 1994 .

Synthesis and neurotrophic activity of nonimmunosuppressant cyclosporin A derivatives.

J. Steiner, G. S. Hamilton, Ling Wei, 2004, Bioorganic & medicinal chemistry letters.

Rigid molecular tweezers: preorganized hosts for electron donor-acceptor complexation in organic solvents

S. Zimmerman, G. S. Hamilton, C. VanZyl, 1989 .

A mild deprotection procedure for tert-butyl esters and tert-butyl ethers using ZnBr2 in methylene chloride

David C. Limburg, G. S. Hamilton, M. Vaal, 2000 .

Asymmetric synthesis of a potent and selective competitive NMDA antagonist

R. Patch, B. Narayanan, J. Ferkany, 1993 .

Synthesis of N-glyoxyl prolyl and pipecolyl amides and thioesters and evaluation of their in vitro and in vivo nerve regenerative effects.

Wei Huang, Hong Guo, David C. Limburg, 2002, Journal of medicinal chemistry.

Synthesis, molecular modeling and biological evaluation of aza-proline and aza-pipecolic derivatives as FKBP12 ligands and their in vivo neuroprotective effects.

Hong Guo, David C. Limburg, H. Valentine, 2003, Bioorganic & medicinal chemistry.

Formation of nitrogen‐containing heterocycles using di(imidazole‐1‐yl)methanimine

David C. Limburg, G. S. Hamilton, Y. Wu, 2003 .

Direct synthesis of guanidines using di(imidazole-1-yl)methanimine.

Sean K. Hamilton, G. S. Hamilton, Y. Wu, 2002, The Journal of organic chemistry.

Microwave-assisted synthesis of N,N'-diaryl cyanoguanidines.

Sean K. Hamilton, Sean K Hamilton, Doug E Wilkinson, 2005, Organic letters.

Direct synthesis of guanidines using di(imidazole-1-yl)methanimine.

Sean K. Hamilton, G. S. Hamilton, Y. Wu, 2002, The Journal of organic chemistry.

Synthesis and Diels-Alder reactions of N-carbalkoxydihydropyridines. Substituent effects on the regiochemistry of reduction of N-carbalkoxypyridinium ions

R. Sundberg, C. Trindle, G. S. Hamilton, 1986 .

3-(3-Pyrrolyl)thiopyrrolidones as precursors of benzo[1,2-b:4,3-b']dipyrroles. Synthesis of intermediates and analogs related to the phosphodiesterase inhibitors PDE I and PDE II and antitumor antibiotic CC-1065

R. Sundberg, J. Laurino, G. S. Hamilton, 1988 .

A Mild Deprotection Procedure for tert‐Butyl Esters and tert‐Butyl Ethers Using ZnBr2 in Methylene Chloride.

David C. Limburg, G. S. Hamilton, M. Vaal, 2000 .

Synthesis and evaluation of chiral bicyclic proline FKBP12 ligands.

David C. Limburg, J. Steiner, B. Thomas, 2003, Bioorganic & medicinal chemistry letters.

Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A

S. Snyder, L. Hester, T. Dawson, 1997, Nature Medicine.

Neural actions of immunophilin ligands.

S. Snyder, D. Sabatini, P. Suzdak, 1998, Trends in pharmacological sciences.

Immunophilins: The next generation

G. S. Hamilton, T. Christine, 2000 .

Neuroprotective effects of inhibitors of dipeptidyl peptidase-iV in vitro and in vivo.

David C. Limburg, J. Steiner, S. Belyakov, 2003, Advances in experimental medicine and biology.

Behavioral pharmacology of NPC 17742, a competitive N-methyl-D-aspartate (NMDA) antagonist.

J. Ferkany, D. Clissold, G. S. Hamilton, 1993, The Journal of pharmacology and experimental therapeutics.

Pharmacological profile of NPC 17742 [2R,4R,5S-(2-amino-4,5-(1, 2-cyclohexyl)-7-phosphonoheptanoic acid)], a potent, selective and competitive N-methyl-D-aspartate receptor antagonist.

R. Patch, J. Ferkany, D. L. Bednar, 1993, The Journal of pharmacology and experimental therapeutics.

Use of parallel-synthesis combinatorial libraries for rapid identification of potent FKBP12 inhibitors.

Hong Guo, David C. Limburg, H. Valentine, 2002, Bioorganic & medicinal chemistry letters.

Solid-phase synthesis of FKBP12 inhibitors: N-sulfonyl and N-carbamoylprolyl/pipecolyl amides.

Hong Guo, H. Valentine, J. Steiner, 2002, Bioorganic & medicinal chemistry letters.

Formation of Nitrogen‐Containing Heterocycles Using Di(imidazole‐1‐yl)methanimine.

David C. Limburg, G. S. Hamilton, Y. Wu, 2003 .

Pharmacology of (2R, 4R, 5S)-2-amino-4,5-(1,2-cyclohexyl)-7-phosphonoheptanoic acid (NPC 17742); a selective, systemically active, competitive NMDA antagonist

J. Ferkany, G. S. Hamilton, J. Willetts, 1993 .

Enzymatic asymmetric synthesis of (2R, 4R, 5S)-2-amino-4,5-(1,2-cyclohexyl)-7-phosphonoheptanoic acid, a potent, selective and competitive NMDA antagonist

R. Patch, B. Narayanan, J. Ferkany, 1993 .

Novel anti-inflammatory compounds prevent CD11b/CD18, alpha M beta 2 (Mac-1)-dependent neutrophil adhesion without blocking activation-induced changes in Mac-1.

J. Perumattam, Y. Feng, R. E. Mewshaw, 1996, The Journal of pharmacology and experimental therapeutics.

Antibody-drug conjugates for cancer therapy: The technological and regulatory challenges of developing drug-biologic hybrids.

G. S. Hamilton, 2015, Biologicals : journal of the International Association of Biological Standardization.

Regeneration of Dopaminergic Function in 6-Hydroxydopamine-Lesioned Rats by Neuroimmunophilin Ligand Treatment

T. Hicks, Chunyi Zhang, M. Poulter, 2001, The Journal of Neuroscience.

Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models.

J. H. Li, P. Suzdak, H. Guo, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Fluorenylalkanoic and benzoic acids as novel inhibitors of cell adhesion processes in leukocytes.

L. Stanton, K. Madden, J. Janczak, 1995, Journal of medicinal chemistry.

Synthesis and biological evaluation of non-peptidic cyclophilin ligands.

T. Moeller, David C. Limburg, J. Steiner, 2003, Journal of medicinal chemistry.

Phosphonoethylphenylalanine derivatives as novel antagonists of non-NMDA ionotropic glutamate receptors

R. Patch, J. Ferkany, D. L. Bednar, 1992 .

FKBP12-binding domain analogues of FK506 are potent, nonimmunosuppressive neurotrophic agents in vitro and promote recovery in a mouse model of Parkinson's disease

P. Suzdak, Wei Huang, Hong Guo, 1997 .