P. Loke

发表

Soluble expression of a functionally active Plasmodium falciparum falcipain-2 fused to maltose-binding protein in Escherichia coli.

L. Goh, T. Sim, Mulkit Singh, 2003, Protein expression and purification.

Replacement of arginine-171 and aspartate-453 in Streptomyces coelicolor malate synthase A by site-directed mutagenesis inactivates the enzyme

L. Goh, T. Sim, P. Loke, 2001, Applied Microbiology and Biotechnology.

PCR-mediated screening and cloning of a malate synthase genefrom Streptomyces griseus NCIMB 9001

T. Sim, P. Loke, J. Wee, 2001 .

Probiotic peanut oral immunotherapy versus oral immunotherapy and placebo in children with peanut allergy in Australia (PPOIT-003): a multicentre, randomised, phase 2b trial.

M. Tang, S. Prescott, Sigrid Pitkin, 2022, The Lancet. Child & adolescent health.

Peanut Oral Immunotherapy: State of the Art.

M. Tang, A. Lozinsky, P. Loke, 2020, Immunology and allergy clinics of North America.

Cloning, heterologous expression and purification of an isocitrate lyase from Streptomyces clavuligerus NRRL 3585.

T. Sim, P. Loke, B. Soh, 2001, Biochimica et biophysica acta.

Statewide prevalence of school children at risk of anaphylaxis and rate of adrenaline autoinjector activation in Victorian government schools, Australia.

M. Tang, S. Dharmage, K. Allen, 2016, The Journal of allergy and clinical immunology.

Molecular cloning, heterologous expression, and functional characterisation of a malate synthase gene from Streptomyces coelicolor A3(2).

T. Sim, P. Loke, 2000, Canadian journal of microbiology.

Molecular cloning and functional characterisation of VanX, a D-alanyl-D-alanine dipeptidase from Streptomyces coelicolor A3(2).

T. Sim, P. Loke, A. Tan, 2002, Research in microbiology.

A Comparison of Three Site-Directed Mutagenesis Kits

T. Sim, P. Loke, 2001, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Mutational analysis of tyrosine-191 in the catalysis of Cephalosporium acremonium isopenicillin N synthase.

T. Sim, P. Loke, 2000, Journal of biochemistry.

Glutamine-230 influences enzyme solubility but not catalysis in Streptomyces clavuligerus isopenicillin N synthase.

T. Sim, P. Loke, 1999, FEMS microbiology letters.

Analysis of glutamines in catalysis in Cephalosporium acremonium isopenicillin N synthase by site-directed mutagenesis.

T. Sim, P. Loke, 1998, Biochemical and biophysical research communications.

Analysis of a conserved arginine R281L in catalysis in Cephalosporium acremonium isopenicillin N synthase

T. Sim, P. Loke, 1998 .

Functional analysis of a conserved aspartate D218 in Cephalosporium acremonium isopenicillin N synthase.

T. Sim, J. Sim, P. Loke, 1997, FEMS microbiology letters.

Purification and characterization of recombinant malate synthase enzymes from Streptomyces coelicolor A3(2) and S. clavuligerus NRRL3585

L. Goh, T. Sim, P. Loke, 2002, Journal of Industrial Microbiology and Biotechnology.

Probiotic peanut oral immunotherapy is associated with long‐term persistence of 8‐week sustained unresponsiveness and long‐lasting quality‐of‐life improvement

M. Tang, K. Jayawardana, Sigrid Pitkin, 2022, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Study protocol of a multicentre, randomised, controlled trial evaluating the effectiveness of probiotic and peanut oral immunotherapy (PPOIT) in inducing desensitisation or tolerance in children with peanut allergy compared with oral immunotherapy (OIT) alone and with placebo (the PPOIT-003 study)

A. DunnGalvin, M. Gold, F. Orsini, 2020, BMJ Open.

The effect of antigen targeting sequences on antibody responses to hepatitis E virus DNA vaccines in rats and sheep.

D. Purcell, David A. Anderson, David A Anderson, 2006, Vaccine.

P29: TREEAT TRIAL: PROTOCOL FOR A RANDOMISED CONTROLLED TRIAL INVESTIGATING THE EFFICACY AND SAFETY OF EARLY INTRODUCTION OF TREE NUTS FOR THE PREVENTION OF TREE NUT ALLERGY IN INFANTS WITH PEANUT ALLERGY

Rachael, A. Ponsonby, Joanne M. Smart, 2022, Internal Medicine Journal.

Mutational analysis of conserved glycines 42 and 256 in Cephalosporium acremonium isopenicillin N synthase.

T. Sim, P. Loke, 2001, Canadian journal of microbiology.

Site-Directed Mutagenesis of Proline-285 to Leucine in Cephalosporium acremonium Isopenicillin N - Synthase Affects Catalysis and Increases Soluble Expression at Higher Temperatures

T. Sim, P. Loke, 2001, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Molecular studies on isopenicillin N synthases

T. Sim, P. Loke, 2000, Applied Microbiology and Biotechnology.

PCR cloning, heterologous expression, and characterization of isopenicillin N synthase from Streptomyces lipmanii NRRL 3584.

T. Sim, P. Loke, C. Ng, 2000, Canadian journal of microbiology.

Site-directed mutagenesis of arginine-89 supports the role of its guanidino side-chain in substrate binding by Cephalosporium acremonium isopenicillin N synthase.

T. Sim, P. Loke, 1999, FEMS microbiology letters.

Mutational evidence for the role of serine-283 in Cephalosporium acremonium isopenicillin N synthase.

T. Sim, P. Loke, 1998, FEMS microbiology letters.

Catalytic activity in Cephalosporium acremonium isopenicillin N synthase does not involve glutamine-234.

T. Sim, P. Loke, 1998, Biochemical and biophysical research communications.

Accuracy of inter‐hospital paediatric appendicitis referrals

C. Kimber, Y. Heloury, E. Oakley, 2012, Emergency medicine Australasia : EMA.

TreEAT trial: Protocol for a randomized controlled trial investigating the efficacy and safety of early introduction of tree nuts for the prevention of tree nut allergy in infants with peanut allergy

Joanne M. Smart, Katherine Lee, K. Perrett, 2023, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Fecal microbial transplantation in a pediatric case of recurrent Clostridium difficile infection and specific antibody deficiency

M. Tang, K. Allen, R. Heine, 2016, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Replacement of Tyrosine-197 and the Corresponding Tyrosine-195 to Isoleucine in Cephalosporium acremonium and Streptomyces clavuligerus Isopenicillin N Synthase

T. Sim, P. Loke, 2001, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Varying approaches to management of IgE-mediated food allergy in children around the world.

M. Levin, M. Ebisawa, S. Sicherer, 2023, Journal of Allergy and Clinical Immunology: In Practice.

Accuracy of inter‐hospital paediatric appendicitis referrals

C. Kimber, Y. Heloury, E. Oakley, 2012, Emergency Medicine Australasia.

Inborn Errors of Immunity in Children With Invasive Pneumococcal Disease: A Multicenter Prospective Study

A. Daley, N. Curtis, T. Connell, 2023, The Pediatric infectious disease journal.

TreEAT trial: Protocol for a randomized controlled trial investigating the efficacy and safety of early introduction of tree nuts for the prevention of tree nut allergy in infants with peanut allergy

Joanne M. Smart, Katherine Lee, K. Perrett, 2023, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.