J. Spénard

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Lack of Effect of Sex and Disease State on the Pharmacokinetics of Porfimer Sodium

J. Houle, S. Bain, Nadine Clervoix, 2006, Clinical pharmacokinetics.

Comparative effects of diltiazem sustained‐release formulation and metoprolol on ambulatory blood pressure and plasma lipoproteins

Y. Lacourciére, L. Poirier, J. Spénard, 1990, Clinical pharmacology and therapeutics.

NCX 1000 Alone or in Combination with Vitamin E Reverses Experimental Nonalcoholic Steatohepatitis in the Rat Similarly to UDCA

P. Haddad, D. Vallerand, A. Brault, 2011, International journal of hepatology.

A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis.

V. de Lédinghen, J. Bastard, P. Sogni, 2011, Journal of hepatology.

Bioavailability of metformin in tablet form using a new high pressure liquid chromatography assay method

J. Thiffault, M. Perrotta, G. Caillé, 1993, Biopharmaceutics & drug disposition.

Comparative pharmacokinetics and pharmacodynamics of two marketed bid formulations of diltiazem in healthy volunteers

M. Grace, D. Gossard, A. Russell, 1993, Biopharmaceutics & drug disposition.

Pharmacokinetics and pharmacodynamics of a slow‐release formulation of diltiazem after the administration of a single and repeated doses to healthy volunteers

D. Gossard, P. du Souich, Y. Lacasse, 1994, Biopharmaceutics & drug disposition.

Massive Diltiazem Overdosage: Clinical and Pharmacokinetic Observations

P. Callegari, G. Caillé, J. Spénard, 1986, Drug intelligence & clinical pharmacy.

Efficacy and Safety of Mesalamine 1 g HS Versus 500 mg BID Suppositories in Mild to Moderate Ulcerative Proctitis: A Multicenter Randomized Study

M. Grace, M. Lamet, C. Dallaire, 2005, Inflammatory bowel diseases.

Efficacy and safety of mesalamine suppositories for treatment of ulcerative proctitis in children and adolescents

J. Kierkuś, M. Heyman, H. Shbaklo, 2010, Inflammatory bowel diseases.

Combining ursodeoxycholic acid or its NO-releasing derivative NCX-1000 with lipophilic antioxidants better protects mouse hepatocytes against amiodarone toxicity.

P. Haddad, A. Elimadi, P. Colin, 2007, Canadian journal of physiology and pharmacology.

A comparison of triamcinolone acetonide nasal aerosol spray and fluticasone propionate aqueous solution spray in the treatment of spring allergic rhinitis.

J. H. Day, M. Gold, P. Small, 1997, The Journal of allergy and clinical immunology.

NCX-1000, a Nitric Oxide–Releasing Derivative of UDCA, Does Not Decrease Portal Pressure in Patients With Cirrhosis: Results of a Randomized, Double-Blind, Dose-Escalating Study

J. Bosch, C. Gagnon, A. Berzigotti, 2010, The American Journal of Gastroenterology.

Diltiazem and Hydrochlorothiazide/Triamterene as Initial Therapy for Mild to Moderate Essential Hypertension

A. Logan, A. Chockalingam, J. Lenis, 1992 .

Bismuth-Based Quadruple Therapy Using a Single Capsule of Bismuth Biskalcitrate, Metronidazole, and Tetracycline Given With Omeprazole Versus Omeprazole, Amoxicillin, and Clarithromycin for Eradication of Helicobacter pylori in Duodenal Ulcer Patients: A Prospective, Randomized, Multicenter, North A

R. Hunt, L. Laine, H. El-Zimaity, 2003, American Journal of Gastroenterology.

Efficacy and safety of single‐triple capsules of bismuth biskalcitrate, metronidazole and tetracycline, given with omeprazole, for the eradication of Helicobacter pylori: an international multicentre study

F. Mégraud, C. O'Morain, T. Borody, 2003, Alimentary pharmacology & therapeutics.

Effects of food and formulation on the relative bioavailability of bismuth biskalcitrate, metronidazole, and tetracycline given for Helicobacter pylori eradication.

M. Grace, C. Tremblay, J. Spénard, 2005, British journal of clinical pharmacology.

Diltiazem pharmacokinetics in elderly volunteers after single and multiple doses

J. Thiffault, A. Russell, G. Caillé, 2010, European Journal of Drug Metabolism and Pharmacokinetics.

The second peak in the serum levels curve after oral administration of a slow-release quinidine dosage form: effect of food.

M. Gagnon, G. Sirois, J. Spénard, 1982, British journal of clinical pharmacology.

A multicenter, partially blinded, randomised study of the efficacy of photodynamic therapy (PDT) using porfimer sodium (POR) for the ablation of high-grade dysplasia (HGD) in Barrett's esophagus (BE): Results of 6-month follow-up

B. Overholt, M. Bronner, M. Dépôt, 2001 .

Pharmacokinetics and Pilot Efficacy of a Mesalazine Rectal Gel in Distal Ulcerative Colitis

M. Grace, G. Aumais, C. Tremblay, 2005, Drugs in R&D.

Rectal tissue, plasma and urine concentrations of mesalazine after single and multiple administrations of 500 mg suppositories to healthy volunteers and ulcerative proctitis patients

G. Aumais, C. Tremblay, F. Martin, 2003, Alimentary pharmacology & therapeutics.

Release of 5‐ASA from Pentasa in patients with Crohn's disease of the small intestine

P. Poitras, M. Picard, J. Spénard, 1995, Alimentary pharmacology & therapeutics.

Intrarectal administration of 5-aminosalicylic acid to rabbits and dogs

C. Meschter, J. Spénard, E. Berryman, 2002, Human & experimental toxicology.

Pharmacokinetics of single intravenous and oral doses of dolasetron mesylate in healthy elderly volunteers.

S. Bourque, J. Spénard, E. Dempsey, 1996, Journal of clinical pharmacology.

Pharmacokinetics of oral diltiazem and five of its metabolites in patients with chronic renal failure

D. Bichet, J. Marc‐aurèle, G. Caillé, 1991, Biopharmaceutics & drug disposition.

Influence of food on the bioavailability of diltiazem and two of its metabolites following the administration of conventional tablets and slow-release capsules.

P. du Souich, F. Varin, G. Caillé, 1990, Biopharmaceutics & drug disposition.

High-performance liquid chromatographic method for the assay of TA-3090 and its pharmacokinetic parameters in healthy volunteers.

G. Caillé, J. Houle, D. Garceau, 1989, Journal of pharmaceutical and biomedical analysis.

Pharmacokinetics of intravenous diltiazem and five of its metabolites in patients with chronic renal failure and in healthy volunteers

D. Bichet, J. Marc‐aurèle, G. Caillé, 1991, Biopharmaceutics & drug disposition.

47 A MULTICENTRIC, DOUBLE-BLIND, RANDOMISED- CONTROLLED TRIAL (RCT) OF HIGH DOSE URSODEOXYCHOLIC ACID IN PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH)

F. Oberti, C. Renou, P. Mathurin, 2009 .

Bismuth-based triple therapy with bismuth subcitrate, metronidazole and tetracycline in the eradication of Helicobacter pylori: a randomized, placebo controlled, double-blind study.

R. Hunt, N. Marcon, D. Owen, 2000, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

Bismuth-based quadruple therapy with bismuth subcitrate, metronidazole, tetracycline and omeprazole in the eradication of Helicobacter pylori.

R. Hunt, N. Marcon, C. Fallone, 2001, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

Pharmacokinetic and clinical parameters of zopiclone and trimipramine when administered simultaneously to volunteers.

P. du Souich, G. Caillé, Y. Lacasse, 1984, Biopharmaceutics & drug disposition.

Morth American randomized trial of single-triple capsule (bismuth subcitrate, metronidazele, tetracycline) plus omeprazole vs. Omeprazole, amoxicillin, and clarithremycin for H. pylori eradication

R. Hunt, L. Laine, H. El-Zimaity, 2001 .

Influence of sex, age and smoking status on patient comfort during gastroscopy with pharyngeal anesthesia by a new benzocaine-tetracaine preparation.

J. Spénard, M. Asselin, A. Farley, 1998, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

Efficacy and Safety of a New Formulation of Pancrelipase (Ultrase MT20) in the Treatment of Malabsorption in Exocrine Pancreatic Insufficiency in Cystic Fibrosis

T. Liou, M. Konstan, J. Kanga, 2010, Gastroenterology research and practice.

Pharmacokinetics and safety of single intravenous and oral doses of dolasetron mesylate in healthy women.

D. Gossard, L. Roberts, M. Castles, 1997, Biopharmaceutics & drug disposition.

Placebo‐controlled comparative study of the anxiolytic activity and of the pharmacokinetics of oral and sublingual lorazepam in generalized anxiety

C. Montigny, J. Ouellette, G. Caillé, 1988, Biopharmaceutics & drug disposition.

Pharmacokinetics of two lorazepam formulations, oral and sublingual, after multiple doses.

G. Caillé, Y. Lacasse, J. Spénard, 1983, Biopharmaceutics & drug disposition.

Chronic Effects of Diltiazem on the Hemodynamic and Sympathoadrenal Tone in Responsive and Nonresponsive Hypertensive Patients at Rest and During Isometric Exercise

R. Nadeau, J. de Champlain, R. Lebeau, 1991, Journal of cardiovascular pharmacology.

Efficacy and safety of mesalamine suppositories for treatment of ulcerative proctitis in children and adolescents

J. Kierkuś, M. Heyman, H. Shbaklo, 2010, Inflammatory bowel diseases.