V. Villa

发表

Amyloid Precursor Protein Modulates ERK‐1 and ‐2 Signaling

G. Schettini, S. Thellung, T. Florio, 2006, Annals of the New York Academy of Sciences.

Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction

A. Simi, A. Pagano, S. Thellung, 2011, Cell Death and Disease.

Characterization of the intracellular mechanisms mediating somatostatin and lanreotide inhibition of DNA synthesis and growth hormone release from dispersed human GH‐secreting pituitary adenoma cells in vitro

S. Arena, G. Schettini, S. Thellung, 2003, Clinical endocrinology.

Recombinant human prion protein fragment 90-231, a useful model to study prion neurotoxicity.

A. Aceto, S. Thellung, T. Florio, 2012, Omics : a journal of integrative biology.

[The activation of the phosphotyrosine phosphatase eta is responsible for the somatostatin inhibition of PCCl3 thyroid cell proliferation].

A. Fusco, S. Arena, G. Schettini, 2001, Minerva endocrinologica.

Expression of Somatostatin Receptor mRNA in Human Meningiomas and their Implication in in vitro Antiproliferative Activity

G. Lapertosa, S. Arena, G. Schettini, 2004, Journal of Neuro-Oncology.

Characterization of the Proapoptotic Intracellular Mechanisms Induced by a Toxic Conformer of the Recombinant Human Prion Protein Fragment 90–231

A. Aceto, G. Schettini, S. Thellung, 2006 .

p38 MAP Kinase Mediates the Cell Death Induced by PrP106–126 in the SH-SY5Y Neuroblastoma Cells

G. Damonte, F. Tagliavini, E. Millo, 2002, Neurobiology of Disease.

Nitric Oxide Production Stimulated by the Basic Fibroblast Growth Factor Requires the Synthesis of Ceramide

G. Damonte, M. Filocamo, G. Spoto, 2002, Annals of the New York Academy of Sciences.

The Phosphotyrosine Phosphatase η Mediates Somatostatin Inhibition of Glioma Proliferation via the Dephosphorylation of ERK1/2

A. Fusco, S. Arena, G. Schettini, 2004, Annals of the New York Academy of Sciences.

Amino‐Terminally Truncated Prion Protein PrP90‐231 Induces Microglial Activation in Vitro

A. Aceto, G. Schettini, M. Bisaglia, 2007, Annals of the New York Academy of Sciences.

Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis.

Gianluca Damonte, Giuseppe Spoto, Umberto Benatti, 2003, Molecular pharmacology.

Quality of Fresh Bovine Milk after Addition of Hypothiocyanite-rich-solution from Lactoperoxidase System

V. P. Bintoro, A. Legowo, A. N. Al-Baarri, 2014 .

Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells

A. Pagano, Roberto Würth, S. Thellung, 2016, Oncotarget.

Peptide Receptor Targeting in Cancer: The Somatostatin Paradigm

Roberto Würth, S. Thellung, A. Bajetto, 2013, International journal of peptides.

Electro-switchable DNA layers for the analysis of antibody-antigen and p53-DNA interactions

V. Villa, 2012 .

Neurodegeneration in Alzheimer Disease: Role of Amyloid Precursor Protein and Presenilin 1 Intracellular Signaling

Claudio Russo, A. Pagano, S. Thellung, 2012, Journal of toxicology.

Emerging Targets in Pituitary Adenomas: Role of the CXCL12/CXCR4-R7 System

Roberto Würth, S. Thellung, T. Florio, 2014, International journal of endocrinology.

Role of Prion Protein Aggregation in Neurotoxicity

S. Thellung, T. Florio, M. Nizzari, 2012, International journal of molecular sciences.

Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor-3-mediated regulation of endothelial nitric oxide synthase and mitogen-activated protein kinase activities.

D. Noonan, A. Albini, M. Culler, 2003, Endocrinology.

Different structural stability and toxicity of PrPARR and PrPARQ sheep prion protein variants

H. Kretzschmar, A. Aceto, S. Thellung, 2007, Journal of neurochemistry.

Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death

K. Cortese, C. Tacchetti, M. Gagliani, 2018, Cell Death & Disease.

Different Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90–231 Neurotoxic Effects in Cerebellar Granule Neurons

M. Robello, S. Thellung, T. Florio, 2017, Neurotoxicity Research.

Novel celecoxib analogues inhibit glial production of prostaglandin E2, nitric oxide, and oxygen radicals reverting the neuroinflammatory responses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide.

M. Robello, F. Novelli, S. Thellung, 2016, Pharmacological research.

Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells

F. Novelli, S. Thellung, T. Florio, 2014, Molecular Neurobiology.

Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells

F. Novelli, S. Thellung, T. Florio, 2014, Molecular Neurobiology.

Intracellular accumulation of a mild‐denatured monomer of the human PrP fragment 90–231, as possible mechanism of its neurotoxic effects

A. Aceto, A. Perico, S. Thellung, 2007, Journal of neurochemistry.

Conformation Dependent Pro-Apoptotic Activity of the Recombinant Human Prion Protein Fragment 90-231

A. Aceto, P. Ballerini, G. Schettini, 2006, International Journal of Immunopathology and Pharmacology.

Different Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90–231 Neurotoxic Effects in Cerebellar Granule Neurons

M. Robello, S. Thellung, T. Florio, 2017, Neurotoxicity Research.

High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein.

A. Aceto, T. Bucciarelli, S. Thellung, 2011, The international journal of biochemistry & cell biology.

Efficacy of Novel Acridine Derivatives in the Inhibition of hPrP90-231 Prion Protein Fragment Toxicity

A. Sparatore, A. Aceto, F. Novelli, 2011, Neurotoxicity Research.

Dual Modulation of ERK1/2 and p38 MAP Kinase Activities Induced by Minocycline Reverses the Neurotoxic Effects of the Prion Protein Fragment 90–231

A. Aceto, A. Simi, S. Thellung, 2009, Neurotoxicity Research.

Apoptotic Cell Death and Impairment of L-Type Voltage-Sensitive Calcium Channel Activity in Rat Cerebellar Granule Cells Treated with the Prion Protein Fragment 106–126

G. Forloni, F. Tagliavini, M. Salmona, 2000, Neurobiology of Disease.

Canine osteosarcoma cell lines contain stem-like cancer cells: biological and pharmacological characterization.

A. Ratto, S. Thellung, A. Bajetto, 2016, The Japanese journal of veterinary research.

Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment

M. Vassalli, M. Robello, S. Thellung, 2012, Neurotoxicity Research.

ERK1/2 and p38 MAP kinases control prion protein fragment 90–231‐induced astrocyte proliferation and microglia activation

A. Aceto, M. Robello, S. Thellung, 2007, Glia.

Prion Protein Fragment 106–126 Induces a p38 MAP Kinase—Dependent Apoptosis in SH‐SY5Y Neuroblastoma Cells Independently from the Amyloid Fibril Formation

G. Damonte, A. Aceto, E. Millo, 2003, Annals of the New York Academy of Sciences.

Contribution of two conserved glycine residues to fibrillogenesis of the 106–126 prion protein fragment. Evidence that a soluble variant of the 106–126 peptide is neurotoxic

G. Damonte, A. Aceto, E. Millo, 2003, Journal of neurochemistry.

The Chemokine SDF1/CXCL12: A Novel Autocrine/Paracrine Factor Involved In Pituitary Adenoma Development

Roberto Würth, S. Thellung, A. Bajetto, 2011 .

Protein analysis by time-resolved measurements with an electro-switchable DNA chip

Frank D. Fischer, U. Rant, J. Knežević, 2013, Nature Communications.

Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment

M. Vassalli, M. Robello, S. Thellung, 2013, Neurotoxicity Research.

Expression in E. coli and purification of recombinant fragments of wild type and mutant human prion protein

G. Damonte, F. Tagliavini, A. Aceto, 2002, Neurochemistry International.

Characterization of the proapoptotic intracellular mechanisms induced by a toxic conformer of the recombinant human prion protein fragment 90-231.

A. Aceto, G. Schettini, S. Thellung, 2006, Annals of the New York Academy of Sciences.

Calcium Binding Promotes Prion Protein Fragment 90–231 Conformational Change toward a Membrane Destabilizing and Cytotoxic Structure

A. Aceto, T. Bucciarelli, B. Maras, 2012, PloS one.