Huanwen Chen

发表

A highly anti-selective asymmetric Henry reaction catalyzed by a chiral copper complex: applications to the syntheses of (+)-spisulosine and a pyrroloisoquinoline derivative.

Zhiyong Wang, Susu Pan, Zhenggen Zha, 2012, Chemistry.

Application of real-time PCR for testing antiviral compounds against Lassa virus, SARS coronavirus and Ebola virus in vitro

S. Günther, C. Drosten, B. Becker-Ziaja, 2004, Antiviral Research.

Total synthesis of atropurpuran

Xiao‐Yu Liu, Yong Qin, W. Nie, 2016, Nature Communications.

Synthesis of oxadiazole-2-oxide derivatives as potential drug candidates for schistosomiasis targeting SjTGR

Yang Hong, Qingqing Guo, Huanwen Chen, 2020, Parasites & vectors.

Novel artemisinin derivatives with potent anticancer activities and the anti-colorectal cancer effect by the mitochondria-mediated pathway.

Y. Liu, Wenyu Lu, Huanwen Chen, 2020, Bioorganic chemistry.

Synthetic approach to the functionalized tricyclic core of atropurpuran

Xiao‐Yu Liu, Yong Qin, Hao Song, 2016 .

Synthesis of the atropurpuran A-ring via an organocatalytic asymmetric intramolecular Michael addition

Yong Qin, F. Xue, Dan Zhang, 2013 .

Synthesis of a novel ring-expanded (“fat”) nucleotide analogue of phosphonomethoxyethylguanine (PMEG) containing the imidazo[4,5-e][1,3]diazepine ring system

R. Hosmane, Huanwen Chen, 2001 .

Total syntheses of (-)-isoschizogamine and (-)-2-hydroxyisoschizogamine.

Yong Qin, Hao Song, Huanwen Chen, 2015, Chemistry.

Total Syntheses of (‐)‐Isoschizogamine and (‐)‐2‐Hydroxyisoschizogamine.

Yong Qin, Hao Song, Huanwen Chen, 2015 .

in vitro inhibition of the measles virus by novel ring-expanded ('fat') nucleoside analogues containing the imidazo[4,5-e]diazepine ring system.

D. Barnard, A. Fattom, R. Sidwell, 2002, Bioorganic & medicinal chemistry letters.

Novel ring-expanded nucleoside analogs exhibit potent and selective inhibition of hepatitis B virus replication in cultured human hepatoblastoma cells.

A. Fattom, E. Kern, R. Hosmane, 2002, Antiviral research.

ACYCLIC NUCLEOSIDE/NUCLEOTIDE ANALOGUES WITH AN IMIDAZOLE RING SKELETON

R. Hosmane, Huanwen Chen, H. M. Chen, 2001, Nucleosides, nucleotides & nucleic acids.

Ring-expanded ("fat") nucleoside and nucleotide analogues exhibit potent in vitro activity against flaviviridae NTPases/helicases, including those of the West Nile virus, hepatitis C virus, and Japanese encephalitis virus.

A. Fattom, C. Liao, H. Schmitz, 2003, Journal of medicinal chemistry.

Characterization of Imidazo[4,5-d]Pyridazine Nucleosides as Modulators of Unwinding Reaction Mediated by West Nile Virus Nucleoside Triphosphatase/Helicase: Evidence for Activity on the Level of Substrate and/or Enzyme

J. Choe, H. Schmitz, R. Hosmane, 2002, Antimicrobial Agents and Chemotherapy.

Synthesis of 1-(2'-O-Methyl-ß-D-ribofuranosyl)-1H-imidazo[4,5-d]pyridazine-4,7(5H,6H)-dione: An Attractive Building Block for Antisense and Triple-helical Applications ‡

R. Hosmane, Huanwen Chen, 2001, Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry.

Potent inhibition of NTPase/helicase of the West Nile Virus by ring-expanded ("fat") nucleoside analogues.

M. Minczuk, A. Fattom, P. Stepien, 2003, Journal of medicinal chemistry.

Synthesis of a novel ring‐expanded nucleoside analogue containing the imidazo[4,5‐e][1,3]diazepine ring system with a guanidinocarbamoyl‐substituted cyclopropylidene group in place of a sugar moiety

D. Baldisseri, R. Hosmane, Huanwen Chen, 2000 .