F. Guéritte

发表

Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step.

S. Betzi, J. Neyts, J. Haiech, 2009, Antiviral research.

Palladium-catalyzed borylation of ortho-substituted phenyl halides and application to the one-pot synthesis of 2,2'-disubstituted biphenyls.

D. Guénard, O. Baudoin, F. Guéritte, 2000, The Journal of organic chemistry.

Phenanthrene derivatives from Appendicula reflexa as new CDK1/cyclin B inhibitors

L. Meijer, O. Lozach, M. Litaudon, 2012 .

7 The Vinca Alkaloids

J. Fahy, F. Guéritte, F. Gueritte, 2005 .

Cytotoxic farnesyl glycosides from Pittosporum pancheri.

M. Litaudon, V. Eparvier, F. Guéritte, 2007, Phytochemistry.

Tonantzitlolones from Stillingia lineata ssp. lineata as potential inhibitors of chikungunya virus

J. Neyts, P. Retailleau, P. Leyssen, 2015 .

Isomeric Eremophilane Lactones from Senecio tsoongianus

Yu Zhao, D. Rankin, S. Parsons, 2004, Chemistry & biodiversity.

Kingianic Acids A–G, Endiandric Acid Analogues from Endiandra kingiana

M. Litaudon, V. Dumontet, K. Mohamad, 2014, Molecules.

Chemical constituents of Anacolosa pervilleana and their antiviral activities.

B. Canard, P. Leyssen, M. Litaudon, 2012, Fitoterapia.

Cytotoxic pentacyclic triterpenoids from Combretum sundaicum and Lantana camara as inhibitors of Bcl-xL/BakBH3 domain peptide interaction.

O. Nosjean, J. Boutin, B. Pfeiffer, 2009, Journal of natural products.

Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship.

B. Monsarrat, T. Cresteil, J. Dubois, 2002, Drug metabolism and disposition: the biological fate of chemicals.

Antiplasmodial benzophenone derivatives from the root barks of Symphonia globulifera (Clusiaceae).

C. Moretti, Soizic Prado, M. Litaudon, 2010, Phytochemistry.

General and recent aspects of the chemistry and structure-activity relationships of taxoids.

F. Guéritte, 2001, Current pharmaceutical design.

Biomimetic total synthesis of meiogynin A, an inhibitor of Bcl-xL and Bak interaction.

F. Roussi, F. Guéritte, A. Leverrier, 2010, The Journal of organic chemistry.

Acetylcholinesterase inhibitors from the leaves of Macaranga kurzii.

M. Litaudon, V. Dumontet, V. Pham, 2012, Journal of natural products.

4-Phenylcoumarins from Mesua elegans with acetylcholinesterase inhibitory activity.

N. Ismail, M. Litaudon, K. Awang, 2010, Bioorganic & medicinal chemistry.

Pentacyclic polyketides from Endiandra kingiana as inhibitors of the Bcl-xL/Bak interaction.

M. Litaudon, K. Awang, F. Guéritte, 2011, Phytochemistry.

Biologically active tetralones from New Caledonian Zygogynum spp.

O. Nosjean, M. Litaudon, V. Dumontet, 2008, Phytochemistry.

Biodiversity as a Source of Potent and Selective Inhibitors of Chikungunya Virus Replication

M. Mahomoodally, B. Canard, A. Gurib-Fakim, 2014 .

Elaboration of vinblastine hybrids using a reactive in situ generated N-carboxyanhydride.

F. Roussi, Marie-Thérèse Martin, F. Guéritte, 2011, Organic & biomolecular chemistry.

Gas-Phase Reactivity of Acylphenols in Electrospray and Matrix-Assisted Laser Desorption Ionization Mass Spectrometry

V. Guérineau, M. Litaudon, O. Laprévote, 2009, European journal of mass spectrometry.

The palladium-catalyzed C-H activation of benzylic gem-dialkyl groups.

O. Baudoin, F. Guéritte, Audrey Herrbach, 2003, Angewandte Chemie.

Asymmetric synthesis of an axially chiral antimitotic biaryl via an atropo-enantioselective Suzuki cross-coupling.

A. Marinetti, D. Guénard, O. Baudoin, 2003, The Journal of organic chemistry.

Comparative pharmacokinetics of antitumor Vinca alkaloids: intravenous bolus injections of navelbine and related alkaloids to cancer patients and rats

J. Barbet, R. Rahmani, J. Cano, 2004, Cancer Chemotherapy and Pharmacology.

Relocation of Aurora B and survivin from centromeres to the central spindle impaired by a kinesin-specific MKLP-2 inhibitor.

O. Rath, Sergey O Tcherniuk, F. Kozielski, 2010, Angewandte Chemie.

Trigocherrin A, the first natural chlorinated daphnane diterpene orthoester from Trigonostemon cherrieri.

P. Allard, P. Leyssen, M. Litaudon, 2012, Organic letters.

Flacourtosides A-F, phenolic glycosides isolated from Flacourtia ramontchi.

B. Canard, P. Leyssen, M. Litaudon, 2012, Journal of natural products.

Recent developments in antitumour taxoids

D. Guénard, J. Dubois, F. Guéritte, 2003 .

Antiplasmodial benzophenones from the trunk latex of Moronobea coccinea (Clusiaceae).

C. Moretti, Soizic Prado, P. Retailleau, 2009, Phytochemistry.

The Design and Synthesis of New Steroidal Compounds as Potential Mimics of Taxoids

F. Roussi, D. Guénard, S. Thoret, 2005 .

In vitro oxidative metabolism study of (-)-rhazinilam.

T. Cresteil, J. Ouazzani, A. Chiaroni, 2006, Bioorganic & medicinal chemistry.

An Efficient One‐Step Synthesis of Piperidin‐2‐yl and Pyrrolidin‐2‐yl Flavonoid Alkaloids through Phenolic Mannich Reactions

T. Nguyen, F. Guéritte, Qian Wang, 2011 .

Practical Synthesis of N-Aryl-o-hydroxyaryl Ketimines

T. Nguyen, F. Guéritte, Qian Wang, 2012 .

Natural Bridged Biaryls with Axial Chirality and Antimitotic Properties

O. Baudoin, F. Guéritte, 2004 .

Application of the palladium-catalyzed borylation/Suzuki coupling (BSC) reaction to the synthesis of biologically active biaryl lactams.

D. Guénard, O. Baudoin, M. Césario, 2002, The Journal of organic chemistry.

Chiral phosphoric acid catalyzed enantioselective transfer hydrogenation of ortho-hydroxybenzophenone N-H ketimines and applications.

T. Nguyen, F. Guéritte, Qian Wang, 2011, Chemistry.

Phosphoric acid-catalyzed enantioselective transfer hydrogenation of N-aryl-ortho-hydroxybenzophenone ketimines

T. Nguyen, F. Guéritte, Hadjira Bousserouel, 2011 .

Chiral phosphoric acid-catalyzed enantioselective transfer hydrogenation of ortho-hydroxyaryl alkyl N-H ketimines.

T. Nguyen, F. Guéritte, Hadjira Bousserouel, 2010, Organic letters.

New Synthesis of Benzo-δ-carbolines, Cryptolepines, and Their Salts: In Vitro Cytotoxic, Antiplasmodial, and Antitrypanosomal Activities of δ-Carbolines, Benzo-δ-carbolines, and Cryptolepines

P. Grellier, F. Marsais, E. Arzel, 2001 .

Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases.

L. Meijer, O. Lozach, P. Retailleau, 2012, Journal of medicinal chemistry.

Synthesis and Biological Evaluation of Novel Compounds Related to 1‐Arylnaphthalene Lignans and Isoquinolines

Yu Zhao, Wei Lu, Junchao Cai, 2005, Chemistry & biodiversity.

Synthesis and biological evaluation of a new series of highly functionalized 7'-homo-anhydrovinblastine derivatives.

F. Gago, J. Bignon, F. Roussi, 2013, Journal of medicinal chemistry.

Role of anhydrovinblastine in the biosynthesis of the antitumor dimeric indole alkaloids

A. Scott, F. Guéritte, S. Lee, 1978 .

Application of a modification of the Polonovski reaction to the synthesis of vinblastine-type alkaloids.

N. Langlois, P. Potier, Y. Langlois, 1976, Journal of the American Chemical Society.

Synthesis of a rhazinilam analogue acting as an inhibitor of tubulin assembly

D. Guénard, C. Thal, S. Thoret, 2000 .

Cytotoxic arylnaphthalene lignans from a Vietnamese acanthaceae, Justicia patentiflora.

A. Kruczynski, J. Bignon, N. Hung, 2005, Journal of natural products.

One-pot synthesis of vinca alkaloids-phomopsin hybrids.

F. Gago, J. Bignon, F. Roussi, 2014, Journal of medicinal chemistry.

Semisynthesis of D-ring modified taxoids: novel thia derivatives of docetaxel.

D. Guénard, J. Dubois, S. Thoret, 2001, The Journal of organic chemistry.

Cytotoxic steroidal alkaloids from Kibatalia laurifolia.

M. Litaudon, V. Pham, Huong Doan Thi Mai, 2011, Journal of natural products.

Bisindole alkaloid artifacts from Gonioma malagasy

M. Litaudon, P. Rasoanaivo, M. Beniddir, 2013 .

Goniomedines A and B: unprecedented bisindole alkaloids formed through fusion of two indole moieties via a dihydropyran unit.

M. Litaudon, P. Rasoanaivo, M. Beniddir, 2012, Organic letters.

Alkylated flavanones from the bark of Cryptocarya chartacea as dengue virus NS5 polymerase inhibitors.

B. Canard, P. Allard, M. Litaudon, 2011, Journal of natural products.

New cytotoxic flavonoids from Cryptocarya infectoria

V. Dumontet, L. Tchertanov, N. Hung, 2001 .

Isolation and characterization of two new drimanes from Zygogynum baillonii and synthesis of analogues

F. Roussi, M. Litaudon, F. Guéritte, 2008 .

Effects of the hydrophobicity of taxoids on their interaction with tubulin.

D. Guénard, M. Adeline, S. Thoret, 2000, Bioorganic & medicinal chemistry.

Synthesis of C2-C3'N-linked macrocyclic taxoids. Novel docetaxel analogues with high tubulin activity.

F. Roussi, D. Guénard, J. Dubois, 2004, Journal of medicinal chemistry.

Sesquiterpenoids and cytotoxic lignans from the bark of Libocedrus chevalieri.

M. Litaudon, V. Dumontet, Ying-Jun Zhang, 2007, Journal of natural products.

Synthesis and cytotoxicity of racemic isodeoxypodophyllotoxin analogues with isoprene-derived side chains.

C. H. Cheng, J. Stöckigt, Yuan-jiang Pan, 2006, Journal of natural products.

Kingianin A: a new natural pentacyclic compound from Endiandra kingiana.

P. Retailleau, M. Litaudon, K. Awang, 2010, Organic letters.

Asymmetric Synthesis of Two Analogues of Meiogynin A

F. Roussi, S. Desrat, F. Guéritte, 2013 .

Synthesis and biological evaluation of A-ring biaryl-carbamate analogues of rhazinilam.

D. Guénard, S. Thoret, O. Baudoin, 2002, Bioorganic & medicinal chemistry.

First total synthesis of phenylpyridine analogues of the antimitotic rhazinilam.

E. Pasquinet, D. Guénard, F. Marsais, 2001, The Journal of organic chemistry.

D-ring substituted rhazinilam analogues: semisynthesis and evaluation of antitubulin activity.

L. Tchertanov, D. Guénard, S. Thoret, 1999, Bioorganic & medicinal chemistry.

Antimitotic agents interacting with tubulin: Synthesis and structure-activity relationships of novel ortho bridged biphenyls of the rhazinilam type

L. Tchertanov, D. Guénard, J. Dubois, 1998 .

Synthesis of Biphenyls Mimicking the Structure of the Antimitotic Rhazinilam.

D. Guénard, J. Dubois, F. Guéritte, 1998, The Journal of organic chemistry.

Semisynthesis and biological evaluation of a novel D-seco docetaxel analogue.

D. Guénard, J. Dubois, S. Thoret, 2006, Organic Letters.

Deletion of the oxetane ring in docetaxel analogues: synthesis and biological evaluation.

D. Guénard, J. Dubois, S. Thoret, 2003, Organic letters.

Synthesis of 5(20)deoxydocetaxel, a new active docetaxel analogue

D. Guénard, J. Dubois, S. Thoret, 2000 .

Novel cyclopeptide and unique flavone from Desmos rostrata. Total synthesis of desmorostratone

B. Bodo, M. Litaudon, V. Pham, 2009 .

Styryllactones and Acetogenins from the Fruits of Goniothalamus macrocalyx

P. Retailleau, M. Litaudon, V. Pham, 2014, Natural product communications.

Novel C2-C3' N-peptide linked macrocyclic taxoids. Part 2: synthesis and biological activities of docetaxel analogues with a peptide side chain at C2 and their macrocyclic derivatives.

Geneviève Aubert, D. Guénard, A. Chiaroni, 2007, Bioorganic & medicinal chemistry.

Cytotoxic sesquiterpenoids from Winteraceae of Caledonian rainforest.

M. Litaudon, C. Apel, V. Dumontet, 2009, Phytochemistry.

Antiplasmodial, antitrypanosomal, and cytotoxic activities of prenylated flavonoids isolated from the stem bark of Artocarpus styracifolius.

M. Litaudon, C. Apel, P. Grellier, 2010, Planta medica.

Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis

M. Litaudon, V. Dumontet, J. Kasenene, 2009, Molecules.

Eudesmane derivatives and other sesquiterpenes from Laggera alata.

Françoise Guéritte, C. H. Cheng, Yu Zhao, 2003, Journal of natural products.

Eudesmane derivatives from Laggera pterodonta.

Yu Zhao, Han-Dong Sun, Qijun Zhang, 2003, Fitoterapia.

Cleistanone: A Triterpenoid from Cleistanthus indochinensis with a New Carbon Skeleton

M. Litaudon, V. Pham, Van Trinh Thi Thanh, 2011 .

Cytotoxic Aryltetralin Lignans from Fruits of Cleistanthus indochinensis

M. Litaudon, V. Pham, V. Nguyen, 2014, Planta Medica.

Prostratin and 12-O-tetradecanoylphorbol 13-acetate are potent and selective inhibitors of Chikungunya virus replication.

L. Delang, J. Neyts, P. Leyssen, 2012, Journal of natural products.

Antiviral chlorinated daphnane diterpenoid orthoesters from the bark and wood of Trigonostemon cherrieri.

B. Canard, P. Leyssen, M. Litaudon, 2012, Phytochemistry.

Cytotoxicity of Rhamnosylanthraquinones and Rhamnosylanthrones from Rhamnus nepalensis.

V. Dumontet, D. Guénard, M. V. Trị, 2001, Journal of natural products.

Enyne- and enediyne-γ-lactones from the bark of Meiogyne cylindrocarpa

M. Litaudon, K. Awang, F. Guéritte, 2012 .

Acylphenols from Myristica crassa as new acetylcholinesterase inhibitors.

M. Litaudon, O. Laprévote, K. Awang, 2008, Planta medica.

Natural Aristolactams and Aporphine Alkaloids as Inhibitors of CDK1/Cyclin B and DYRK1A

L. Meijer, O. Lozach, B. Bodo, 2013, Molecules.

Turrianes from Kermadecia rotundifolia as new acetylcholinesterase inhibitors

M. Litaudon, V. Dumontet, M. Beniddir, 2010 .

Cytotoxic turrianes of Kermadecia elliptica from the New Caledonian rainforest.

B. Pfeiffer, M. Litaudon, V. Dumontet, 2008, Phytochemistry.

Cycloartane triterpenes from the leaves of Neoboutonia macrocalyx L.

J. Kabasa, V. Dumontet, I. Florent, 2014, Phytochemistry.

Partial synthesis of vinblastine-type alkaloids

N. Langlois, P. Potier, Y. Langlois, 1975 .

Pyrrolidinoindoline alkaloids from Psychotria oleoides and Psychotria lyciiflora.

L. Sérani, O. Laprévote, P. Potier, 1999, Journal of natural products.

APPLICATION OF A MODIFICATION OF THE POLONOVSKI REACTION TO THE SYNTHESIS OF VINBLASTINE-TYPE ALKALOIDS

N. Langlois, P. Potier, Y. Langlois, 1977 .

Synthesis and biological evaluation of vinca alkaloids and phomopsin hybrids.

Marcel Knossow, F. Roussi, D. Guénard, 2009, Journal of medicinal chemistry.

Benzofurans from Styrax agrestis as acetylcholinesterase inhibitors: structure-activity relationships and molecular modeling studies.

Marc Litaudon, V. Guérineau, M. Litaudon, 2011, Journal of natural products.

Elaboration of Simplified Vinca Alkaloids and Phomopsin Hybrids

F. Roussi, S. Thoret, F. Guéritte, 2010, Chemical biology & drug design.

Cytotoxic lignans from fruits of Cleistanthus indochinensis: synthesis of cleistantoxin derivatives.

Marc Litaudon, Pascal Retailleau, Françoise Guéritte, 2012, Journal of natural products.

Radioimmunoassay for the Determination of the Indole Alkaloid Vindoline in Catharanthus

M. Zenk, N. Langlois, P. Potier, 1980 .

First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors.

V. Tan, P. Colas, O. Lozach, 2011, Biotechnology journal.

A New Steroid Derivative Stabilizes G-Quadruplexes and Induces Telomere Uncapping in Human Tumor Cells

Jean-Louis Mergny, J. Mergny, J. Riou, 2007, Molecular Pharmacology.

Structure of human glycolate oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole.

Y. Lindqvist, F. Lederer, J. Bourhis, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

New inhibitors of prion replication that target the amyloid precursor.

E. Jacquet, F. Mouthon, M. Charvériat, 2009, The Journal of general virology.

Diarylheptanoid glucosides from Pyrostria major and their antiprotozoal activities

Marc Litaudon, Mehdi A. Beniddir, Françoise Guéritte, 2012 .

Cytotoxic Flavonoids and a-Pyrones from Cryptocarya o bovata

V. Dumontet, N. Hung, A. Chiaroni, 2004 .

Seasonal variation of neutral and basic taxoid contents in shoots of European Yew (Taxus baccata)

D. Guénard, I. Hook, M. Adeline, 1999 .

Syntheses of two cytotoxic sinapyl alcohol derivatives and isolation of four new related compounds from Ligularia nelumbifolia.

Wei Lu, Junchao Cai, Xiao-jiang Hao, 2002, Journal of natural products.

New skeletal rearrangements of C and D rings of a 13-oxobaccatin III derivative

D. Guénard, A. Chiaroni, J. Dubois, 1998 .

Synthesis of novel macrocyclic docetaxel analogues. Influence of their macrocyclic ring size on tubulin activity.

F. Roussi, D. Guénard, J. Dubois, 2003, Journal of medicinal chemistry.

An in silico approach for the discovery of CDK5/p25 interaction inhibitors.

Vincent B. C. Tan, Bing Zhang, Françoise Guéritte, 2011, Biotechnology journal.

High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Implications for inhibitor specificity and drug design.

F. Lederer, D. Guénard, Zhi-Wei Chen, 2012, Biochimie.

Toxicarioside M, a new cytotoxic 10β-hydroxy-19-nor-cardenolide from Antiaris toxicaria.

M. Litaudon, C. Levrier, B. Kiremire, 2012, Fitoterapia.

Tigliane diterpenes from Croton mauritianus as inhibitors of chikungunya virus replication.

L. Delang, J. Neyts, P. Leyssen, 2014, Fitoterapia.

Cytotoxic prenylated isoflavone and bipterocarpan from Millettia pachyloba.

M. Litaudon, V. Pham, V. Nguyen, 2010, Planta medica.

Alkaloids and styryllactones from the leaves of Goniothalamus tamirensis

M. Litaudon, V. Pham, V. Nguyen, 2013 .

Searching for iridoids from tropical plant species: Detection, isolation and potential uses as raw chiral material

M. Litaudon, V. Dumontet, C. Remeur, 2012 .

Biodiversity as a source of small molecules for pharmacological screening: libraries of plant extracts

Marc Litaudon, Françoise Guéritte, M. Litaudon, 2011 .

Malayanines A and B, two novel limonoids from Chisocheton erythrocarpus Hiern

M. Litaudon, K. Mohamad, K. Awang, 2012 .

Rearranged diterpenoids from the biotransformation of ent-trachyloban-18-oic acid by Rhizopus arrhizus.

P. Retailleau, M. Litaudon, J. Ouazzani, 2010, Journal of natural products.

A Dimeric sesquiterpenoid from a Malaysian Meiogyne as a new inhibitor of Bcl-xL/BakBH3 domain peptide interaction.

O. Nosjean, J. Boutin, M. Litaudon, 2009, Journal of natural products.

A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds

M. Litaudon, G. Marti, P. Grellier, 2010, Molecules.

New potent vinca alkaloids resulting from an unexpected isomerization

F. Roussi, S. Thoret, F. Guéritte, 2012 .

Cytotoxic monotetrahydrofuran acetogenins from Disepalum plagioneurum.

V. Eparvier, V. Nguyen, Marie-Thérèse Martin, 2006, Journal of natural products.

Cytotoxic flavonoids and alpha-pyrones from Cryptocarya obovata.

N. Van Hung, V. Dumontet, A. Chiaroni, 2004, Journal of natural products.

Synthesis and biological evaluation of B-ring analogues of (-)-rhazinilam.

D. Guénard, A. Chiaroni, S. Thoret, 2006, Bioorganic & medicinal chemistry.