D. Sugiyama

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Effect of 17β-Estradiol-d-17β-Glucuronide on the Rat Organic Anion Transporting Polypeptide 2-Mediated Transport Differs Depending on Substrates

T. Abe, H. Kusuhara, Y. Sugiyama, 2002 .

Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation.

H. Takakusa, Yuka Yamamoto, N. Kurikawa, 2017, Bioorganic & medicinal chemistry.

Design, synthesis, and pharmacological evaluation of a novel series of hormone sensitive lipase inhibitor.

Yuka Yamamoto, N. Kurikawa, Nobumi Nagaoka, 2017, Bioorganic & medicinal chemistry.

Transepithelial transport of organic anions across the choroid plexus: possible involvement of organic anion transporter and multidrug resistance-associated protein.

Y. Sugiyama, H. Suzuki, M. Hanano, 1999, The Journal of pharmacology and experimental therapeutics.

Multiple Human Isoforms of Drug Transporters Contribute to the Hepatic and Renal Transport of Olmesartan, a Selective Antagonist of the Angiotensin II AT1-Receptor

Kazuya Maeda, Yuichi Sugiyama, Teruo Okano, 2007, Drug Metabolism and Disposition.

Drug-Drug Interaction Risk Assessment of Esaxerenone as a Perpetrator by In Vitro Studies and Static and Physiologically Based Pharmacokinetic Models

M. Yamada, S. Inoue, T. Ishizuka, 2020, Drug Metabolism and Disposition.

Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier.

T. Abe, H. Kusuhara, Y. Sugiyama, 2001, The Journal of pharmacology and experimental therapeutics.

Characterization of the Efflux Transport of 17β-Estradiol-d-17β-glucuronide from the Brain across the Blood-Brain Barrier

T. Abe, H. Kusuhara, Y. Sugiyama, 2001 .

Involvement of Multidrug Resistance Associated Protein 1 (Mrp1) in the Efflux Transport of 17β Estradiol-D-17β-Glucuronide (E217βG) Across the Blood-Brain Barrier

H. Kusuhara, Y. Sugiyama, D. Sugiyama, 2003, Pharmaceutical Research.

Contribution of Organic Anion Transporter 3 (Slc22a8) to the Elimination of p-Aminohippuric Acid and Benzylpenicillin across the Blood-Brain Barrier

H. Kusuhara, Y. Sugiyama, R. Kikuchi, 2003, Journal of Pharmacology and Experimental Therapeutics.

Functional Characterization of Rat Brain-specific Organic Anion Transporter (Oatp14) at the Blood-Brain Barrier

S. Ishikawa, H. Aburatani, H. Kusuhara, 2003, Journal of Biological Chemistry.

Discovery of novel pyrrole derivatives as potent agonists for the niacin receptor GPR109A.

T. Nishizawa, T. Aburatani, K. Kono, 2020, Bioorganic & medicinal chemistry letters.

Involvement of multidrug resistance associated protein 1 (Mrp1) in the efflux transport of 17beta estradiol-D-17beta-glucuronide (E217betaG) across the blood-brain barrier.

H. Kusuhara, Y. Sugiyama, D. Sugiyama, 2003, Pharmaceutical research.

Identification of a novel boronic acid as a potent, selective, and orally active hormone sensitive lipase inhibitor.

Yuka Yamamoto, N. Kurikawa, D. Sugiyama, 2016, Bioorganic & medicinal chemistry.

Characterization of CS-023 (RO4908463), a novel parenteral carbapenem antibiotic, and meropenem as substrates of human renal transporters.

E. Kamiyama, T. Tokui, T. Hirota, 2007, Drug metabolism and pharmacokinetics.

Comparative Inhibitory Effects of Different Compounds on Rat Oatp1 (Slc21a1)- and Oatp2 (Slc21a5)-Mediated Transport

T. Abe, H. Kusuhara, Y. Sugiyama, 2002, Pharmaceutical Research.

Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions.

H. Kusuhara, Y. Sugiyama, H. Endou, 2002, The Journal of pharmacology and experimental therapeutics.

Critical Impact of Drug-Drug Interactions via Intestinal CYP3A in the Risk Assessment of Weak Perpetrators Using Physiologically Based Pharmacokinetic Models

Kengo Watanabe, S. Yamashita, M. Yamada, 2020, Drug Metabolism and Disposition.

Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites

Kazuhito Shiosakai, T. Izumi, H. Takakusa, 2011, Drug Metabolism and Disposition.

Microsoft Word-74715577-file00

Kazuhito Shiosakai, H. Takakusa, N. Okudaira, 2011 .

Combination of glutathione trapping and time-dependent inhibition assays as a predictive method drugs generating highly reactive metabolites

Kazuhito Shiosakai, T. Izumi, H. Takakusa, 2011 .

Culture Period-Dependent Change of Function and Expression of ATP-Binding Cassette Transporters in Caco-2 Cells

E. Kamiyama, D. Nakai, S. Miura, 2009, Drug Metabolism and Disposition.

EFFECT OF 17 (cid:1) -ESTRADIOL- D -17 (cid:1) -GLUCURONIDE ON THE RAT ORGANIC ANION TRANSPORTING POLYPEPTIDE 2-MEDIATED TRANSPORT DIFFERS DEPENDING ON SUBSTRATES

H. Kusuhara, Y. Sugiyama, Y. Shitara, 2002 .

Effect of 17 beta-estradiol-D-17 beta-glucuronide on the rat organic anion transporting polypeptide 2-mediated transport differs depending on substrates.

T. Abe, H. Kusuhara, Y. Sugiyama, 2002, Drug Metabolism And Disposition.