W. Rycroft

发表

The novel NK1 receptor antagonist MK–0869 (L–754,030) and its water soluble phosphoryl prodrug, L–758,298, inhibit acute and delayed cisplatin-induced emesis in ferrets

S. Tye, R. Hargreaves, F. D. Tattersall, 2000, Neuropharmacology.

The tachykinin NK1 receptor antagonist CP-99,994 attenuates cisplatin induced emesis in the ferret.

R. Hargreaves, F. D. Tattersall, R. Hill, 1993, European journal of pharmacology.

Enantioselective inhibition of ampomorphine-induced emesis in the ferret by the neurokinin1 receptor antagonist CP-99,994

R. Hargreaves, F. D. Tattersall, R. Hill, 1994, Neuropharmacology.

Postponement of satiety by blockade of brain cholecystokinin (CCK-B) receptors.

S. Iversen, C. Dourish, W. Rycroft, 1989, Science.

Structural optimization affording 2-(R)-(1-(R)-3, 5-bis(trifluoromethyl)phenylethoxy)-3-(S)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a potent, orally active, long-acting morpholine acetal human NK-1 receptor antagonist.

J. Metzger, M. Maccoss, D. Macintyre, 1998, Journal of medicinal chemistry.

Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists.

Mark T. Kershaw, S. Boyce, J. Krause, 2010, Journal of medicinal chemistry.

2-Aryl indole NK1 receptor antagonists: optimisation of the 2-aryl ring and the indole nitrogen substituent.

K. Tsao, C. Swain, G. Hollingworth, 2001, Bioorganic & medicinal chemistry letters.

Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs.

J. Metzger, M. Maccoss, D. Macintyre, 2000, Journal of medicinal chemistry.

N-heteroaryl-2-phenyl-3-(benzyloxy)piperidines: a novel class of potent orally active human NK1 antagonists.

J. Metzger, D. Macintyre, R. Hargreaves, 1996, Journal of medicinal chemistry.

In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists.

M. Maccoss, R. Hargreaves, C. Swain, 1997, European journal of pharmacology.

Tachykinin NK1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatin in ferrets

J. Metzger, D. Macintyre, R. Hargreaves, 1996, Neuropharmacology.

An investigation into the discriminative stimulus and reinforcing properties of the CCKB-receptor antagonist, L-365,260 in rats

S. Iversen, G. Bentley, M. Tricklebank, 1994, Neuropeptides.

Novel lactam NK1 antagonists with anti-emetic activity.

K. Tsao, R. Kilburn, C. Swain, 2006, Bioorganic & medicinal chemistry letters.

Brain penetration of aprepitant, a substance P receptor antagonist, in ferrets.

R. Hargreaves, R. Sanchez, R. Bakhtiar, 2003, Drug metabolism and disposition: the biological fate of chemicals.

4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists II.

K. Tsao, C. Swain, G. Hollingworth, 2002, Bioorganic & medicinal chemistry letters.

Enantiospecific inhibition of emesis induced by nicotine in the house musk shrew (Suncus murinus) by the neurokinin1 (NK1) receptor antagonist CP-99,994

R. Hargreaves, R. Hill, M. Cascieri, 1995, Neuropharmacology.

The behavioral effects of heptyl physostigmine, a new cholinesterase inhibitor, in tests of long-term and working memory in rodents

G. Dawson, S. Iversen, G. Bentley, 1991, Pharmacology Biochemistry and Behavior.

An orally active, water-soluble neurokinin-1 receptor antagonist suitable for both intravenous and oral clinical administration.

R. Hargreaves, C. Swain, B. Williams, 2001, Journal of medicinal chemistry.

An Inverse Agonist Selective for α5 Subunit-Containing GABAA Receptors Enhances Cognition

N Collinson, B. Everitt, J. Atack, 2006, Journal of Pharmacology and Experimental Therapeutics.

An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties.

G. Dawson, J. Atack, D. O'connor, 2004, Journal of medicinal chemistry.

RELIGIOUS LIBERTY IN LATIN AMERICA? By George P. Howard. Philadelphia: Westminster Press, 1944. $2.00. GREATER GOOD NEIGHBOR POLICY By Wade Crawford Barclay, Chicago-New York, Willet, Clark & Co., 1945. $2.50.

W. Rycroft, 1945, Church History.