Le Wang

发表

Functional human induced hepatocytes (hiHeps) with bile acid synthesis and transport capacities: A novel in vitro cholestatic model

C. Chen, L. Hui, Guoyu Pan, 2016, Scientific Reports.

Organic anion-transporting polypeptides contribute to the hepatic uptake of berberine

Guoyu Pan, Cheng-gang Huang, Zhi-tao Wu, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism

Guoyu Pan, Chen Chen, Xiaoting Tian, 2015, Drug Metabolism and Disposition.

Supplemental data : The hepatobiliary disposition of timosaponin B 2 is highly dependent on influx / efflux transporters but not metabolism

Guoyu Pan, Xiaoting Tian, Chenggang Huang, 2014 .

Inhibition of hepatic cytochrome P450 enzymes and sodium/bile acid cotransporter exacerbates leflunomide-induced hepatotoxicity

C. Chen, Guoyu Pan, Yang Luan, 2016, Acta Pharmacologica Sinica.

Different structures of berberine and five other protoberberine alkaloids that affect P-glycoprotein-mediated efflux capacity

Weiliang Zhu, Yu Yu, Guoyu Pan, 2018, Acta Pharmacologica Sinica.

18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway

Guo-zhen Xing, Jin Ren, Li-kun Gong, 2018, Acta Pharmacologica Sinica.

Altered Expression of Transporters, its Potential Mechanisms and Influences in the Liver of Rodent Models Associated with Diabetes Mellitus and Obesity

Xuena Lin, Guoyu Pan, Lei He, 2016, European Journal of Drug Metabolism and Pharmacokinetics.

In vitro study of the growth, development and pathogenicity responses of Fusarium oxysporum to phthalic acid, an autotoxin from Lanzhou lily

Q. Ren, Zhongkui Xie, Yubao Zhang, 2015, World journal of microbiology & biotechnology.

Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver

Sheng Yao, Qiang-qiang Deng, Yaru Xue, 2020, Acta Pharmacologica Sinica.

The involvement of multidrug and toxin extrusion protein 1 in the distribution and excretion of berberine

Yaru Xue, Guoyu Pan, Yun-fei Lin, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance–Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator–Activated Receptor α Activation

Hu Zhou, Guoyu Pan, Lei-lei Ma, 2018, Molecular Pharmacology.

Altered Expression of Transporters, its Potential Mechanisms and Influences in the Liver of Rodent Models Associated with Diabetes Mellitus and Obesity

Xuena Lin, Guoyu Pan, Lei He, 2016, European Journal of Drug Metabolism and Pharmacokinetics.

Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance–Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator–Activated Receptor α Activation

Hu Zhou, Guoyu Pan, Lei-lei Ma, 2018, Molecular Pharmacology.