D. Fernández

发表

Cyclobutane-containing peptides: evaluation as novel metallocarboxypeptidase inhibitors and modelling of their mode of action.

F. Avilés, R. Ortuño, J. Vendrell, 2009, Bioorganic & medicinal chemistry.

Structure-aided development of small molecule inhibitors of ENPP1, the extracellular phosphodiesterase of the immunotransmitter cGAMP

Lingyin Li, Jacqueline A. Carozza, Mark Smith, 2020, bioRxiv.

Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library.

F. Avilés, D. Reverter, I. Pallarès, 2017, ACS medicinal chemistry letters.

The X‐Ray Structure of Carboxypeptidase A Inhibited by a Thiirane Mechanism‐Based Inhibitor

F. Avilés, S. Mobashery, J. Vendrell, 2010, Chemical Biology and Drug Design.

Analysis of a new crystal form of procarboxypeptidase B: further insights into the catalytic mechanism.

F. Avilés, I. Pallarès, E. Boix, 2010, Biopolymers.

Progress in metallocarboxypeptidases and their small molecular weight inhibitors.

F. Avilés, I. Pallarès, J. Vendrell, 2010, Biochimie.

A new type of five-membered heterocyclic inhibitors of basic metallocarboxypeptidases.

F. Avilés, J. Vendrell, D. Fernández, 2009, European journal of medicinal chemistry.

Human carboxypeptidase E. Isolation and characterization of the cDNA, sequence conservation, expression and processing in vitro.

C. Hall, C. Monfries, E. Manser, 1990, The Biochemical journal.

Structural and Functional Analysis of the Complex between Citrate and the Zinc Peptidase Carboxypeptidase A

F. Avilés, I. Pallarès, E. Boix, 2011, Enzyme research.

Thioxophosphoranyl aryl- and heteroaryloxiranes as the representants of a new class of metallocarboxypeptidase inhibitors.

F. Avilés, O. Illa, V. Branchadell, 2008, Bioorganic & medicinal chemistry.

Metallocarboxypeptidases and their inhibitors: recent developments in biomedically relevant protein and organic ligands.

F. Avilés, I. Pallarès, J. Vendrell, 2013, Current medicinal chemistry.

Aromatic Organic Compounds as Scaffolds for Metallocarboxypeptidase Inhibitor Design

F. Avilés, J. Vendrell, D. Fernández, 2009, Chemical biology & drug design.

The molecular analysis of Trypanosoma cruzi metallocarboxypeptidase 1 provides insight into fold and substrate specificity

F. Avilés, M. Solà, F. Gomis-Rüth, 2008, Molecular microbiology.

STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition

T. Weiss, Lingyin Li, D. Fernández, 2019, Cell.

Caught after the Act: a human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide.

À. Bayés, F. Avilés, M. Solà, 2007, Biochemistry.

Structural and functional characterization of binding sites in metallocarboxypeptidases based on Optimal Docking Area analysis

Daniel Fernández, Juan Fernández-Recio, Josep Vendrell, 2007, Proteins.

A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus.

I. Pallarès, S. Russi, M. Monod, 2013, Acta crystallographica. Section D, Biological crystallography.

Processing and secretion of human carboxypeptidase E by C6 glioma cells.

L. Lim, E. Manser, D. Fernández, 1991, The Biochemical journal.

A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus.

I. Pallarès, S. Russi, M. Monod, 2013, Acta crystallographica. Section D, Biological crystallography.

Progress in metallocarboxypeptidases and their small molecular weight inhibitors.

F. Avilés, I. Pallarès, J. Vendrell, 2010, Biochimie.

The X‐Ray Structure of Carboxypeptidase A Inhibited by a Thiirane Mechanism‐Based Inhibitor

F. Avilés, S. Mobashery, J. Vendrell, 2010, Chemical biology & drug design.

Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid).

J. Fernández-Recio, W. Bode, F. Avilés, 2008, Acta crystallographica. Section D, Biological crystallography.