S. Davies

发表

The selective 5-HT1B receptor inverse agonist 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4'-piperidine] (SB-224289) potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.

J. Hagan, D. Middlemiss, G. W. Price, 1998, Journal of medicinal chemistry.

Biarylcarbamoylindolines are novel and selective 5-HT(2C) receptor inverse agonists: identification of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a potential antidepressant/anxiolytic agent.

D. Middlemiss, S. Lightowler, S. Bromidge, 2000, Journal of medicinal chemistry.

Asymmetric Fluorination Approach to the Scalable Synthesis of a SYK Inhibitor

M. Gray, S. Leach, N. Curtis, 2015 .

The identification of potent and selective imidazole-based inhibitors of B-Raf kinase.

David M. Wilson, A. Reith, F. King, 2006, Bioorganic & medicinal chemistry letters.

Significance of the trimethylsilyl moiety in synthetic carborane transformations: conversion of nido-(Me3Si)2C2B4H6 to nido-(Me3Si)2C4B8H10 by thermal elimination of trimethylsilane, an important advance in carborane chemistry

N. Hosmane, S. Davies, M. Dehghan, 1985 .

4-acyl-1-(4-aminoalkoxyphenyl)-2-ketopiperazines as a novel class of non-brain-penetrant histamine H3 receptor antagonists.

Christopher Browning, Helen Connor, David M. Wilson, 2007, Journal of medicinal chemistry.

Serine derived NK1 antagonists. 1: The effect of modifications to the serine substituents.

A. Macleod, G. Chicchi, M. Kurtz, 1998, Bioorganic & medicinal chemistry letters.

The identification of potent, selective and CNS penetrant furan-based inhibitors of B-Raf kinase.

Robert P. Davis, David M. Wilson, A. Reith, 2008, Bioorganic & medicinal chemistry letters.

(1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: further optimisation as highly potent and selective MSK-1-inhibitors.

David M. Wilson, A. Takle, D. Dean, 2005, Bioorganic & medicinal chemistry letters.

(1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: a novel class of potent MSK-1-inhibitors.

David M. Wilson, J. Witherington, S. Garland, 2005, Bioorganic & Medicinal Chemistry Letters.

Model studies on a synthetically facile series of N-substituted phenyl-N'-pyridin-3-yl ureas leading to 1-(3-pyridylcarbamoyl) indolines that are potent and selective 5-HT(2C/2B) receptor antagonists.

S. Bromidge, S. Dabbs, D. Davies, 1999, Bioorganic & medicinal chemistry.