J. Allen

发表

Synthesis and structure-activity relationship of trisubstituted thiazoles as Cdc7 kinase inhibitors.

Guomin Yao, M. Bartberger, J. Bailis, 2014, European journal of medicinal chemistry.

Discovery of Novel Protein Fucosylation Inhibitors and Development of a Manufacturing Process To Prepare Inhibitor 6,6,6-Trifluorofucose

S. Caille, J. Allen, 2016 .

Facile Modulation of Antibody Fucosylation with Small Molecule Fucostatin Inhibitors and Cocrystal Structure with GDP-Mannose 4,6-Dehydratase.

J. B. Jordan, J. McCarter, M. Mujacic, 2016, ACS chemical biology.

Design and synthesis of novel amide AKT1 inhibitors with selectivity over CDK2.

Matthew R. Lee, Shiwen Zhang, J. Lofgren, 2011, Bioorganic & medicinal chemistry letters.

Azole-based inhibitors of AKT/PKB for the treatment of cancer.

Daniel J. Freeman, Q. Zeng, Guomin Yao, 2010, Bioorganic & medicinal chemistry letters.

Piperazine oxadiazole inhibitors of acetyl-CoA carboxylase.

M. Fielden, M. Véniant, Minghan Wang, 2013, Journal of medicinal chemistry.

Telescoped Process to Manufacture 6,6,6-Trifluorofucose via Diastereoselective Transfer Hydrogenation: Scalable Access to an Inhibitor of Fucosylation Utilized in Monoclonal Antibody Production.

S. W. Roberts, Michal M. Achmatowicz, Christopher J. Borths, 2016, The Journal of organic chemistry.

Improvement of the synthesis and pharmacokinetic properties of chromenotriazolopyrimidine MDM2-p53 protein-protein inhibitors.

J. Oliner, S. Olson, Q. Ye, 2011, Bioorganic & medicinal chemistry letters.

The optimization of aminooxadiazoles as orally active inhibitors of Cdc7.

T. Bush, M. Rong, K. Sham, 2013, Bioorganic & medicinal chemistry letters.

Identification of small molecule inhibitors of proline-rich tyrosine kinase 2 (Pyk2) with osteogenic activity in osteoblast cells.

W. Richards, Matthew R. Lee, D. Bauer, 2009, Bioorganic & medicinal chemistry letters.

N-substituted azaindoles as potent inhibitors of Cdc7 kinase.

Guomin Yao, M. Bartberger, E. Doherty, 2013, Bioorganic & medicinal chemistry letters.

New air-stable catalysts for general and efficient suzuki-miyaura cross-coupling reactions of heteroaryl chlorides.

M. Martinelli, M. Faul, P. Reider, 2006, Organic letters.

Highly Regio- and Enantioselective Catalytic Hydrogenation of Enamides in Conjugated Diene Systems: Synthesis and Application of γ,δ-Unsaturated Amino Acids

M. Burk, J. Allen, W. Kiesman, 1998 .

A Mild Amide to Carbamate Transformation

J. Allen, and Mark J. Burk, 1997 .

Discovery and optimization of chromenotriazolopyrimidines as potent inhibitors of the mouse double minute 2-tumor protein 53 protein-protein interaction.

Xin Huang, Klaus Michelsen, Michael D Bartberger, 2009, Journal of medicinal chemistry.

On the total synthesis and determination of the absolute configuration of rishirilide B: exploitation of subtle effects to control the sense of cycloaddition of o-quinodimethides.

S. Danishefsky, M. Hentemann, J. Allen, 2003, Chemistry.

A convenient cross-coupling route to α,β,γ,δ-unsaturated amino acids

M. Burk, K. Stoffan, J. Allen, 1997 .

Catalytic asymmetric hydrogenation of β-substituted α,β,γ,δ-unsaturated amino acids

M. Burk, J. Allen, W. Kiesman, 1999 .

Highly Regio‐ and Enantioselective Catalytic Hydrogenation of Enamides in Conjugated Diene Systems: Synthesis and Application of γ,δ‐Unsaturated Amino Acids.

M. Burk, J. Allen, W. Kiesman, 1998 .

Discovery of a covalent inhibitor of KRASG12C (AMG 510) for the treatment of solid tumors.

N. Chen, J. McCarter, K. Rex, 2019, Journal of medicinal chemistry.

n-Pentenyl Glycosyl Orthoesters as Versatile Intermediates in Oligosaccharide Synthesis. The Proteoglycan Linkage Region1

B. Fraser-Reid, J. Allen, 1999 .

Unmasking Fucosylation: from Cell Adhesion to Immune System Regulation and Diseases.

H. Hsu, J. Mountz, Jun Li, 2018, Cell chemical biology.

Thermal Intermolecular Hetero Diels—Alder Cycloadditions of Aldehydes and Imines via o‐Quinone Dimethides.

S. Danishefsky, M. Hentemann, J. Allen, 2000 .

Phosphonopeptides as Antibacterial Agents: Alaphosphin and Related Phosphonopeptides

S. W. Holmes, L. J. Nisbet, C. Hassall, 1979, Antimicrobial Agents and Chemotherapy.

Half-life extension of peptidic APJ agonists by N-terminal lipid conjugation.

Sara C. Humphreys, Ji Ma, L. Miranda, 2020, Bioorganic & medicinal chemistry letters.

Recent Advances in Acetyl-CoA Carboxylase Inhibitors

Matthew P Bourbeau, Wei-Peng Gu, J. Allen, 2010 .

Cytochrome P450-mediated epoxidation of 2-aminothiazole-based AKT inhibitors: identification of novel GSH adducts and reduction of metabolic activation through structural changes guided by in silico and in vitro screening.

Q. Zeng, G. E. Wohlhieter, Guomin Yao, 2010, Chemical research in toxicology.

The total synthesis of (+/-)-rishirilide B.

S. Danishefsky, J. G. Allen, J. Allen, 2001, Journal of the American Chemical Society.

N-substituted azaindoles as potent inhibitors of Cdc7 kinase.

Guomin Yao, M. Bartberger, E. Doherty, 2013, Bioorganic & medicinal chemistry letters.

Emerging targets in osteoporosis disease modification.

C. Fotsch, P. Babij, J. Allen, 2010, Journal of medicinal chemistry.