Shane A Worthge

A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease.

J. Purcell, A. Syed, J. Marsh, 2014, Human molecular genetics.

Effects of flanking sequences and cellular context on subcellular behavior and pathology of mutant HTT.

J. Purcell, A. Syed, J. Marsh, 2020, Human molecular genetics.

Miles to go (mtgo) encodes FNDC3 proteins that interact with the chaperonin subunit CCT3 and are required for NMJ branching and growth in Drosophila.

A. Bardwell, L. Bardwell, J. Purcell, 2019, Developmental biology.

Comparative study of naturally occurring huntingtin fragments in Drosophila points to exon 1 as the most pathogenic species in Huntington's disease.

David W. Colby, J. Purcell, J. Marsh, 2015, Human molecular genetics.