A. Kotake

发表

Dose Escalation Safety and Tolerance Study of the Competitive NMDA Antagonist Selfotel (CGS 19755) in Neurosurgery Patients

G. Steinberg, M. Yenari, M. Powell, 1998, Clinical neuropharmacology.

Differential haemin-mediated restoration of cytochrome P-450 N-demethylases after inactivation by allylisopropylacetamide.

M. Correia, L. Bornheim, A. Kotake, 1985, The Biochemical journal.

Effects of pregnancy on the cytochrome P-450 system in mice.

G. Lambert, A. Kotake, H. Lietz, 1987, Biochemical pharmacology.

Effects of antioxidants on metabolism of aromatic polycyclic hydrocarbons.

L. Wattenberg, A. Kotake, J. Speier, 1976, Advances in enzyme regulation.

High-performance liquid chromatography technique for resolving multiple forms of hepatic membrane-bound cytochrome P-450.

Y. Funae, A. Kotake, 1980, Proceedings of the National Academy of Sciences of the United States of America.

The caffeine breath test and caffeine urinary metabolite ratios in the Michigan cohort exposed to polybrominated biphenyls: a preliminary study.

D. Schoeller, G. Lambert, S. Spielberg, 1990, Environmental health perspectives.

The caffeine CO2 breath test: Dose response and route of N‐demethylation in smokers and nonsmokers

D. Schoeller, G. Lambert, A. Baker, 1982, Clinical pharmacology and therapeutics.

Comparison of the phenacetin and aminopyrine breath tests: Effect of liver disease, inducers and cobaltous chloride

D. Schoeller, G. Lambert, A. Baker, 1985, Hepatology.

Effects of CGS-15943A on the relaxations produced by adenosine analogs in human blood vessels.

F. Douglas, Syed Jamal Mustafa, G. Brown, 1990, European journal of pharmacology.

New high-performance liquid chromatographic assay for plasma doxorubicin.

N. Vogelzang, A. Kotake, R. A. Larson, 1985, Journal of chromatography.

The effect of age, gender, and sexual maturation on the caffeine breath test.

D. Schoeller, G. Lambert, A. Kotake, 1986, Developmental pharmacology and therapeutics.

The CO2 breath tests as monitors of the cytochrome P450 dependent mixed function monooxygenase system.

D. Schoeller, G. Lambert, A. Kotake, 1983, Progress in clinical and biological research.

Variations in demethylation of N-methylnaltrexone in mice, rats, dogs, and humans.

E. Burton, L. I. Goldberg, C. E. McCoy, 1989, Xenobiotica; the fate of foreign compounds in biological systems.

Clinical Utility of Breath Tests for the Assessment of Hepatic Function

D. Schoeller, A. Baker, A. Kotake, 1983, Seminars in liver disease.

Effects of dietary protein on theophylline pharmacokinetics and caffeine and aminopyrine breath tests

D. Schoeller, M. Frederiksen, A. Kotake, 1986, Clinical pharmacology and therapeutics.

Reversal of the inhibitory effect of lipid peroxides on the hepatic cytochrome P-450 monooxygenase system by a soluble factor from liver and a commercial isocitric dehydrogenase preparation from hog heart.

G. Mannering, L. Deloria, A. Kotake, 1975, Biochemical and biophysical research communications.

The effect of diazepam on the metabolism of methadone by the liver of methadone-dependent rats.

A. Takemori, A. Kotake, T. Spaulding, 1974, Drug metabolism and disposition: the biological fate of chemicals.

The aminopyrine breath test does not correlate with histologic disease severity in patients with cholestasis

D. Schoeller, A. Baker, P. S. Krager, 1987, Hepatology.

Comparison of hepatic microsomal drug-metabolizing systems from rats fed crude and purified diets.

E. Jeffery, T. Guenthner, G. Mannering, 1976, Drug metabolism and disposition: the biological fate of chemicals.

Microsomal spectral properties and narcotic N-demethylase activity in methadone-dependent rats.

A. Takemori, A. Kotake, T. Spaulding, 1976, Drug metabolism and disposition: the biological fate of chemicals.

The in vivo measurement of expired 14CO2 derived from the N-demethylation of aminopyrine as a reflection of the in vitro hepatic cytochrome P-450 drug-metabolism activity in rats.

A. Kotake, J. Latts, B. Schreider, 1982, Drug metabolism and disposition: the biological fate of chemicals.

Aminopyrine infusion breath test for the determination of changes in P450 metabolism in vivo.

A. Kotake, S. K. Kuwahara, B. Schreider, 1995, Xenobiotica; the fate of foreign compounds in biological systems.

The in vivo evaluation of the effect of age and sex on the developmental profile of aminopyrine N-demethylase activity in the newborn rat.

A. Kotake, R. M. Starr, 1982, Drug metabolism and disposition: the biological fate of chemicals.

Effects of linoleic acid hydroperoxide on the hepatic monooxygenase systems of microsomes from untreated, phenobarbital-treated, and 3-methylcholanthrene-treated rats.

E. Jeffery, A. Kotake, R. E. Azhary, 1977, Molecular pharmacology.

Pharmacokinetic Screening of o-Naphthoquinone 5-Lipoxygenase Inhibitors

J. Wasley, David R. Jones, F. Douglas, 1990, Pharmaceutical Research.

Inhibition of Cholera‐Toxin-Stimulated Intestinal Secretion by CGS 9343B in Rats: A Specific Calmodulin Inhibitor

E. Chang, R. Fedorak, F. Douglas, 1989, Journal of Pediatric Gastroenterology and Nutrition - JPGN.

Direct measurement of aminopyrine N-demethylase and antipyrine hydroxylase activities in a monolayer rat primary isolated hepatocyte system.

A. Kotake, 1981, Biochemical pharmacology.

1 – Selfotel (CGS19755)

M. Schmutz, D. Murphy, D. Sauer, 1997 .