J. Darnowski

发表

Taurolidine Antiadhesive Properties on Interaction with E. coli; Its Transformation in Biological Environment and Interaction with Bacteria Cell Wall

A. Goldberg, F. Caruso, M. Rossi, 2010, PloS one.

Bortezomib Inhibits Nuclear Factor-κB–Dependent Survival and Has Potent In vivo Activity in Mesothelioma

C. Porta, D. Fennell, L. Mutti, 2007, Clinical Cancer Research.

Combination Drug Therapy

P. Calabresi, J. Darnowski, 2005, Definitions.

Quantitative analysis of 3'-azido-3'-deoxythymidine incorporation into DNA in human colon tumor cells.

M. Sharma, J. Darnowski, J. Darnowski, 1995, Bioconjugate chemistry.

Mechanistic and antineoplastic evaluation of taurolidine in the DU145 model of human prostate cancer

D. Chatterjee, P. Calabresi, L. Cousens, 2004, Cancer Chemotherapy and Pharmacology.

High‐dose intravenous zidovudine with 5‐fluorouracil and leucovorin. A phase I trial

M. Dudley, M. Posner, J. Bigley, 1992, Cancer.

High-Dose Intravenous Zidovudine with 5-Fluorouracil and Leucovorin

J. Clark, M. Dudley, M. Posner, 1992 .

Bortezomib Inhibits Nuclear Factor- K B ^ Dependent Survival and Has Potent In vivo Activity in Mesothelioma Preclinical

C. Porta, D. Fennell, F. Gasparri, 2007 .

Role of p21 in Apoptosis and Senescence of Human Colon Cancer Cells Treated with Camptothecin*

Wenyi Wei, J. Sedivy, P. Pantazis, 2002, The Journal of Biological Chemistry.

Pharmacokinetics and Pharmacodynamics of High‐Dose Zidovudine Administered as a Continuous Infusion in Patients With Cancer

M. Dudley, M. Posner, J. Darnowski, 1995, Pharmacotherapy.

Human recombinant interferon alpha-2a plus 3'-azido-3'-deoxythymidine. Synergistic growth inhibition with evidence of impaired DNA repair in human colon adenocarcinoma cells.

P. Davol, J. Darnowski, F. A. Goulette, 1997, Biochemical pharmacology.

Hydroxyurea enhances 3′‐azido‐3′‐deoxythymidine (AZT) cytotoxicity in human chronic myeloid leukemia models *

E. Ottaviani, S. Tura, P. Tosi, 1994, European journal of haematology.

Tissue-specific enhancement of uridine utilization and 5-fluorouracil therapy in mice by benzylacyclouridine.

R. Handschumacher, J. Darnowski, 1985, Cancer research.

Enhancement of fluorouracil therapy by the manipulation of tissue uridine pools.

R. Handschumacher, J. Darnowski, 1989, Pharmacology & therapeutics.

Reduction of 9-nitrocamptothecin-triggered apoptosis in DU-145 human prostate cancer cells by ectopic expression of 14-3-3zeta.

L. Goodglick, P. Pantazis, C. Braastad, 2004, International journal of oncology.

Tissue uridine pools: evidence in vivo of a concentrative mechanism for uridine uptake.

R. Handschumacher, J. Darnowski, 1986, Cancer research.

Enhancement of 5-fluoro-2'-deoxyuridine antineoplastic activity by 5-benzyloxybenzyloxybenzylacyclouridine in a human colon carcinoma cell line.

E. Chu, S. Chu, Z. H. Chen, 1992, Cancer research.

Phase I clinical and pharmacological studies of benzylacyclouridine, a uridine phosphorylase inhibitor.

E. Chu, J. Leffert, B. Burtness, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Decreased host toxicity in vivo during chronic treatment with 5-flourouracil

R. Stolfi, C. Lau-cam, Daniel S. Martin, 2004, Cancer Chemotherapy and Pharmacology.

Phase II study of 5-fluoruracil leucovorin and azidothymidine in patients with metastatic colorectal cancer

Jeffrey W. Clark, W. Sikov, B. Cole, 2005, Journal of Cancer Research and Clinical Oncology.

A role for MAP kinase in the antitumor activity of a nucleoside analog

S. Freeman, P. Calabresi, K. Whartenby, 2002, Cancer Gene Therapy.

Circadian rhythm of hepatic uridine phosphorylase activity and plasma concentration of uridine in mice.

S. Soong, K. Park, S. Cha, 1990, Biochemical pharmacology.

Benzylacyclouridine reverses azidothymidine-induced marrow suppression without impairment of anti-human immunodeficiency virus activity.

A. Falcone, M. Wiemann, P. Calabresi, 1990, Blood.

Different effect of benzylacyclouridine on the toxic and therapeutic effects of azidothymidine in mice

A. Falcone, P. Calabresi, R. Ruprecht, 1990 .

Benzylacyclouridine. Pharmacokinetics, metabolism and biochemical effects in mice.

R. Handschumacher, J. Darnowski, 1988, Biochemical pharmacology.

Oral zidovudine, continuous-infusion fluorouracil, and oral leucovorin calcium: a phase I study.

G. Curt, J. Clark, M. Posner, 1990, Journal of the National Cancer Institute.

Different effect of benzylacyclouridine on the toxic and therapeutic effects of azidothymidine in mice.

A. Falcone, P. Calabresi, I. Brunetti, 1990, Blood.

Concentrative uridine transport by murine splenocytes: kinetics, substrate specificity, and sodium dependency.

C. Holdridge, R. Handschumacher, J. Darnowski, 1987, Cancer research.

RKIP Sensitizes Prostate and Breast Cancer Cells to Drug-induced Apoptosis*

B. Aggarwal, J. Sedivy, P. Pantazis, 2004, Journal of Biological Chemistry.

Thrombospondin-1 plus irinotecan: a novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor xenografts in mice

P. Calabresi, G. Allegrini, J. Darnowski, 2004, Cancer Chemotherapy and Pharmacology.

Recombinant interferon α2a synergistically enhances ganciclovir-mediated tumor cell killing in the herpes simplex virus thymidine kinase system

S. Freeman, P. Calabresi, K. Whartenby, 1999, Cancer Gene Therapy.

Clarithromycin does not affect phosphorylation of zidovudine in vitro

M. Dudley, J. Darnowski, A. Strayer, 1996, Antimicrobial agents and chemotherapy.

JAK-Mediated Signaling Inhibits Fas Ligand-Induced Apoptosis Independent of De Novo Protein Synthesis1

L. Cousens, J. Darnowski, F. A. Goulette, 2005, The Journal of Immunology.

The antibacterial drug taurolidine induces apoptosis by a mitochondrial cytochrome c-dependent mechanism.

P. Pantazis, Zhiyong Han, J. Wyche, 2002, Anticancer Research.

Novo Protein Synthesis DeLigand-Induced Apoptosis Independent of JAK-Mediated Signaling Inhibits Fas

L. Cousens, J. Darnowski, F. A. Goulette, 2004 .

Stat3 Cleavage by Caspases

Y. E. Chin, D. Chatterjee, Ying-Jie Guan, 2006, Journal of Biological Chemistry.

Taurolidine: cytotoxic and mechanistic evaluation of a novel antineoplastic agent.

P. Calabresi, J. Darnowski, J. Darnowski, 2001, Cancer research.

Isolated pelvic perfusion for unresectable cancer using a balloon occlusion technique.

H. Wanebo, L. Leenen, L. Leenen, 1993, Archives of surgery.

Taurolidine: preclinical evaluation of a novel, highly selective, agent for bone marrow purging

P. Calabresi, D. Chatterjee, J. Darnowski, 2002, Bone Marrow Transplantation.

5-Fluorouracil enhances azidothymidine cytotoxicity: in vitro, in vivo, and biochemical studies.

A. Falcone, P. Calabresi, I. Brunetti, 1990, Cancer Research.