K. Hutchings

发表

Synthesis and antibacterial activity of the C-7 side chain of 3-aminoquinazolinediones.

H. D. Showalter, M. Huband, M. Shapiro, 2008, Bioorganic & medicinal chemistry letters.

Stereoselective synthesis of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile.

H. D. Showalter, H. Showalter, S. Murphy, 2012, The Journal of organic chemistry.

Rational protein engineering in action: the first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus.

B. Beattie, E. Fauman, B. Finzel, 2008, Journal of structural biology.

Antibacterial Therapy (PPAT) To Validate PPAT as a Target for -Phosphopantetheine Adenylyltransferase ' Discovery of Inhibitors of 4

M. Johnstone, Ning Gao, Jason Thresher, 2014 .

Discovery of Inhibitors of 4′-Phosphopantetheine Adenylyltransferase (PPAT) To Validate PPAT as a Target for Antibacterial Therapy

H. Ni, M. Johnstone, S. Lahiri, 2013, Antimicrobial Agents and Chemotherapy.

Discovery and SAR of benzyl phenyl ethers as inhibitors of bacterial phenylalanyl-tRNA synthetase.

J. Warmus, P. Toogood, Y. Smith, 2009, Bioorganic & medicinal chemistry letters.

NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin

D. Bernstein, J. Domagala, W. Wold, 2022, Molecular pharmaceutics.

Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis

R. Neubig, R. Treisman, B. Spencer‐Dene, 2017, Scientific Reports.

5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma.

R. Neubig, A. Haak, D. Khanna, 2019, Journal of medicinal chemistry.

Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma.

R. Neubig, D. Khanna, R. Sorenson, 2017, Bioorganic & medicinal chemistry letters.