D. Fan

发表

AntiCD3Fv fused to human interleukin-3 deletion variant redirected T cells against human acute myeloid leukemic stem cells

Xiuli Zhang, Xiaolong Zhang, Ming Yang, 2015, Journal of Hematology & Oncology.

PHII-7 inhibits cell growth and induces apoptosis in leukemia cell line K562 as well as its MDR- counterpart K562/A02 through producing reactive oxygen species.

Yahui Ding, Ming Yang, D. Xiong, 2013, European journal of pharmacology.

Mesenchymal stem cells deliver and release conditionally replicative adenovirus depending on hepatic differentiation to eliminate hepatocellular carcinoma cells specifically.

Xiaolong Zhang, Y. Ru, D. Xiong, 2016, Cancer letters.

Redirection of CD4+ and CD8+ T lymphocytes via an anti-CD3 × anti-CD19 bi-specific antibody combined with cytosine arabinoside and the efficient lysis of patient-derived B-ALL cells

Jianxiang Wang, Yan Yan, Xiaolong Zhang, 2015, Journal of Hematology & Oncology.

Bispecific CD3-HAC carried by E1A-engineered mesenchymal stromal cells against metastatic breast cancer by blocking PD-L1 and activating T cells

Jianxiang Wang, Xiaolong Zhang, M. Hao, 2019, Journal of Hematology & Oncology.

Sorcin silencing inhibits epithelial-to-mesenchymal transition and suppresses breast cancer metastasis in vivo

Yun-hui Hu, E. Yagüe, Ming Yang, 2013, Breast Cancer Research and Treatment.

Cytosine arabinoside promotes cytotoxic effect of T cells on leukemia cells mediated by bispecific antibody.

Jianxiang Wang, Yan Yan, Wei Li, 2013, Human gene therapy.

Mesenchymal stromal cells as vehicles of tetravalent bispecific Tandab (CD3/CD19) for the treatment of B cell lymphoma combined with IDO pathway inhibitor d-1-methyl-tryptophan

Xiaolong Zhang, D. Xiong, Leisheng Zhang, 2017, Journal of Hematology & Oncology.

The development of bispecific antibodies and their applications in tumor immune escape

Xiaolong Zhang, D. Xiong, D. Fan, 2017, Experimental Hematology & Oncology.

Anoikis induction and metastasis suppression by a new integrin αvβ3 inhibitor in human melanoma cell line M21

Hui Peng, Yongci Zhang, Ming Yang, 2011, Investigational New Drugs.

An Engineered Fusion Protein Anti-CD19(Fab)-LDM Effectively Inhibits ADR-Resistant B Cell Lymphoma

Y. Zhen, Ming Yang, D. Xiong, 2019, Front. Oncol..

A Novel Blockade CD47 Antibody With Therapeutic Potential for Cancer

Jianxiang Wang, M. Hao, D. Xiong, 2021, Frontiers in Oncology.

Efficient inhibition of human B-cell lymphoma xenografts with an anti-CD20 x anti-CD3 bispecific diabody.

Hui Peng, Zhen-ping Zhu, Min Yang, 2002, Cancer letters.

E1A-engineered human umbilical cord mesenchymal stem cells as carriers and amplifiers for adenovirus suppress hepatocarcinoma in mice

Zong-fang Li, Xiaolong Zhang, Hongbo R. Luo, 2016, Oncotarget.

Inhibition of human B-cell lymphoma by an anti-CD20 antibody and its chimeric F(ab')2 fragment via induction of apoptosis.

Hui Peng, Zhen-ping Zhu, Ming Yang, 2004, Cancer letters.

Apoptosis of Raji cells by an anti-CD20 antibody HI47 and its fragments.

Chun-zheng Yang, D. Fan, D. Xiong, 2004, Leukemia research.

Efficacy of anti-CD20 chimeric Fab’ fragment on proliferation of B lymphoma cells

Hui Peng, Zhen-ping Zhu, Chun-zheng Yang, 2001 .

Influence of the calmodulin antagonist EBB on cyclin B1 and Cdc2-p34 in human drug-resistant breast cancer MCF-7/ADR cells

Xu-Guang Shi, Yan-hong Cheng, Ming Yang, 2008 .

Co-expression of cytokeratin 8 and breast cancer resistant protein indicates a multifactorial drug-resistant phenotype in human breast cancer cell line.

Zhen-ping Zhu, Jing Qi, Chun-zheng Yang, 2008, Life sciences.

Surface expression of anti‐CD3scfv stimulates locoregional immunotherapy against hepatocellular carcinoma depending on the E1A‐engineered human umbilical cord mesenchymal stem cells

Xiao-Long Zhang, Yang Lu, D. Fan, 2017, International journal of cancer.

In vitro activity of bleomycin, tallysomycin S10b, and liblomycin against fresh human tumor cells.

J. Ajani, R. Newman, G. Spitzer, 1989, Cancer research.

Down‐regulation of c‐fos by shRNA sensitizes adriamycin‐resistant MCF‐7/ADR cells to chemotherapeutic agents via P‐glycoprotein inhibition and apoptosis augmentation

Xiuli Zhang, D. Xiong, Hongwei Peng, 2013, Journal of cellular biochemistry.

A novel indirubin derivative PHII-7 potentiates adriamycin cytotoxicity via inhibiting P-glycoprotein expression in human breast cancer MCF-7/ADR cells.

Rong Liu, Xiuli Zhang, Yin-liang Xie, 2011, European journal of pharmacology.

Human umbilical cord mesenchymal stem cells as vehicles of CD20-specific TRAIL fusion protein delivery: a double-target therapy against non-Hodgkin's lymphoma.

Hongwei Peng, Dongsheng Xiong, Ming Yang, 2013, Molecular pharmaceutics.

Expression of ABCB5 gene in hematological malignances and its significance

Xiuli Zhang, Wei Li, Yan Yan, 2012, Leukemia & lymphoma.

Comparison of antitumor activity of standard and investigational drugs at equivalent granulocyte-macrophage colony-forming cell inhibitory concentrations in the adhesive tumor cell culture system: an in vitro method of screening new drugs.

J. Ajani, W. Brock, G. Spitzer, 1987, European Journal of Cancer and Clinical Oncology.

Efficient inhibition of multidrug-resistant human tumors with a recombinant bispecific anti-P-glycoprotein × anti-CD3 diabody

Z. Zhu, Y. Xu, L. Qin, 2004, Leukemia.

The novel structure make LDM effectively remove CD123+ AML stem cells in combination with interleukin 3

J. Qian, Jianxiang Wang, Rong Liu, 2015, Cancer biology & therapy.

Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis.

G. Mills, J. Arbeit, S. Krajewski, 2010, Cancer research.

Mesenchymal stem cells as delivery vectors for anti-tumor therapy.

D. Xiong, D. Fan, Zhen-zhen Li, 2015, Stem cell investigation.

Efficient Inhibition of Human B-cell Lymphoma in SCID Mice by Synergistic Antitumor Effect of Human 4-1BB Ligand/Anti-CD20 Fusion Proteins and Anti-CD3/Anti-CD20 Diabodies

Zhen-ping Zhu, Rong Liu, Wenguo Jiang, 2010, Journal of immunotherapy.

A novel antibody–drug conjugate anti-CD19(Fab)-LDM in the treatment of B-cell non-Hodgkin lymphoma xenografts with enhanced anticancer activity

Y. Zhen, Ming Yang, Yuan Zhou, 2016, Journal of drug targeting.

A Novel CD3/BCMA Bispecific T-cell Redirecting Antibody for the Treatment of Multiple Myeloma

Jianxiang Wang, Xiaomin Lei, Xiaolong Zhang, 2021, Journal of immunotherapy.

Systemic administration of mesenchymal stem cells loaded with a novel oncolytic adenovirus carrying a bispecific T cell engager against hepatocellular carcinoma

D. Xiong, Lei Yang, Yang Lu, 2023, Oncoimmunology.

Suppression of orthotopically implanted hepatocarcinoma in mice by umbilical cord-derived mesenchymal stem cells with sTRAIL gene expression driven by AFP promoter.

Jianxiang Wang, Ming Yang, D. Xiong, 2014, Biomaterials.

Suppression of orthotopically implanted hepatocarcinoma in mice by umbilical cord-derived mesenchymal stem cells with sTRAIL gene expression driven by AFP promoter.

Jianxiang Wang, Ming Yang, D. Xiong, 2014, Biomaterials.

Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis.

G. Mills, J. Arbeit, S. Krajewski, 2010, Cancer research.