Andrew Sharpe

发表

Insights into the Formation Mechanisms of Si−OR Monolayers from the Thermal Reactions of Alcohols and Aldehydes with Si(111)−H1

P. Allongue, R. Boukherroub, S. Morin, 2000 .

Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma.

A. Ebens, C. Noland, J. Lyssikatos, 2019, Journal of Medicinal Chemistry.

Discovery and Optimization of Triazolopyrimidinone Derivatives as Selective NLRP3 Inflammasome Inhibitors.

M. Bock, C. Gabel, M. Holloway, 2022, ACS medicinal chemistry letters.

Discovery of a novel class of D-amino acid oxidase (DAO) inhibitors with the Schrödinger computational platform

Markus K. Dahlgren, L. Frye, T. Day, 2021 .

Use of temporary tethers in the intramolecular [2+2] photocycloaddition reactions of tetrahydrophthalimide derivatives: a new approach to complex tricyclic lactones

K. Booker‐Milburn, Şirin Gülten, Andrew Sharpe, 2007 .

Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors.

T. Ceska, W. Pitt, A. Platt, 2007, Bioorganic & medicinal chemistry letters.

7-Methoxyfuro[2,3-c]pyridine-4-carboxamides as PDE4 inhibitors: a potential treatment for asthma.

H. Dyke, J. Montana, J. Oxford, 2002, Bioorganic & medicinal chemistry letters.

Quinazolinethiones and quinazolinediones, novel inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships.

N. C. Ray, H. Dyke, W. Pitt, 2005, Bioorganic & medicinal chemistry letters.

Intramolecular Photocycloaddition of N‐Alkenyl Substituted Maleimides: A Potential Tool for the Rapid Construction of Perhydroazaazulene Alkaloids

K. Booker‐Milburn, C. Anson, M. Murray, 2001 .

Photocycloaddition of N-4-alkenyl substituted unsaturated imides

K. Booker‐Milburn, Andrew Sharpe, Richard F. Dainty, 1998 .

Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors.

N. C. Ray, H. Dyke, W. Pitt, 2005, Bioorganic & medicinal chemistry letters.

8-Methoxyquinoline-5-carboxamides as PDE4 inhibitors: a potential treatment for asthma.

H. Dyke, J. Montana, J. Oxford, 2002, Bioorganic & medicinal chemistry letters.

Saturated and partially unsaturated carbocycles

K. Booker‐Milburn, Andrew Sharpe, 1996 .

Sequential Ring-Opening/Cyclisation Reactions of Bicyclo[4.2.0]oct-7-enes for the Synthesis of Cyclooctadiene Fused Lactones: Model Studies Towards the Total Synthesis of Pachylactone

K. Booker‐Milburn, Andrew Sharpe, F. Jiménez, 1999 .

Stereoselective Intermolecular [2+2] photocycloaddition reactions of tetrahydrophthalic anhydride and derivatives with alkenols and alkynols

K. Booker‐Milburn, Andrew Sharpe, Andrew J. White, 1999 .

Model Studies Towards the Total Synthesis of Pachylactone

K. Booker‐Milburn, Andrew Sharpe, F. Jiménez, 1995 .

Intramolecular Photocycloaddition of N-Alkenyl Substituted Maleimides: A Potential Tool for the Rapid Construction of Perhydroazaazulene Alkaloids.

K. Booker‐Milburn, C. Anson, M. Murray, 2002 .

Diastereoselective Intramolecular Photochemical [2+2] Cycloaddition Reactions of Tethered L-(+)-Valinol Derived Tetrahydrophthalimides

K. Booker‐Milburn, Andrew Sharpe, S. Gulten, 1997 .

Tetrahydrophthalic Anhydride and Imide: Remarkably Efficient Partners in Photochemical [2+2] Cycloaddition Reactions With Alkenols and Alkynols

K. Booker‐Milburn, Andrew Sharpe, J. Cowell, 1996 .

Photocycloaddition of N-4-Alkenyl Substituted Unsaturated Imides.

K. Booker‐Milburn, Andrew Sharpe, Richard F. Dainty, 1998 .

Discovery of a Novel Class of d-Amino Acid Oxidase Inhibitors Using the Schrödinger Computational Platform.

L. Frye, J. Tierney, M. Svensson, 2022, Journal of medicinal chemistry.

Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode.

Michael D. Goldsmith, Douglas W. Thomson, M. Convery, 2021, Journal of medicinal chemistry.

Synthesis and profile of SCH351591, a novel PDE4 inhibitor.

H. Dyke, J. Montana, J. Oxford, 2002, Bioorganic & medicinal chemistry letters.

Novel indole inhibitors of IMPDH from fragments: synthesis and initial structure-activity relationships.

W. Pitt, A. Ratcliffe, A. F. Haughan, 2006, Bioorganic & medicinal chemistry letters.

Low molecular weight indole fragments as IMPDH inhibitors.

W. Pitt, A. Ratcliffe, A. F. Haughan, 2006, Bioorganic & medicinal chemistry letters.