J. E. Brunsveld

发表

Forskolin induced swelling (FIS) assay in intestinal organoids to guide eligibility for compassionate use treatment in a CF patient with a rare genotype.

J. Beekman, H. Heijerman, B. Aalbers, 2022, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

High-throughput functional assay in cystic fibrosis patient-derived organoids allows drug repurposing

M. C. Hagemeijer, J. Beekman, C. K. van der Ent, 2022, ERJ Open Research.

Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia

L. Kapitein, W. Nijenhuis, C. V. van Drunen, 2022, Life Science Alliance.

CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank.

H. Clevers, J. Mullenders, R. van Boxtel, 2020, Cell stem cell.

CFTR modulator response measurements in subjects with cystic fibrosis using 2D differentiated nasal epithelia converted into spheroids

L. Kapitein, W. Nijenhuis, C. V. van Drunen, 2021, bioRxiv.

Running title: CFTR drug assay with airway organoids

L. Kapitein, W. Nijenhuis, G. Amatngalim, 2021 .

Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids

H. Clevers, R. van Boxtel, Maarten H. Geurts, 2021, Life Science Alliance.

FDA-Approved Drug Screening in Patient-Derived Organoids Demonstrates Potential of Drug Repurposing for Rare Cystic Fibrosis Genotypes

H. Oppelaar, E. Dompeling, E. Weersink, 2022, bioRxiv.

Optical nanoscopy reveals SARS-CoV-2-induced remodeling of human airway cells

A. Akhmanova, L. Kapitein, W. Nijenhuis, 2021, bioRxiv.

Forskolin-induced organoid swelling is associated with long-term cystic fibrosis disease progression

G. Koppelman, H. Oppelaar, M. M. van der Eerden, 2022, European Respiratory Journal.

FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes.

J. Roukema, M. C. Hagemeijer, A. Vonk, 2023, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Exploring intrinsic variability between cultured nasal and bronchial epithelia in cystic fibrosis

G. Amatngalim, J. Beekman, C. K. van der Ent, 2023, Scientific reports.