Kevin J. Wilson

发表

Delayed and Prolonged Histone Hyperacetylation with a Selective HDAC1/HDAC2 Inhibitor.

C. Kenific, Melissa Chenard, A. Kral, 2014, ACS medicinal chemistry letters.

Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2).

J. Grimm, Melissa Chenard, A. Kral, 2009, Bioorganic & medicinal chemistry letters.

Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2).

Melissa Chenard, A. Kral, B. Haines, 2008, Bioorganic & medicinal chemistry letters.

Suppression of racemization in the carbonylation of amino acid-derived aryl triflates

J. Grimm, D. Witter, Kevin J. Wilson, 2007 .

Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability.

T. Fischmann, M. Altman, X. Fradera, 2019, Journal of medicinal chemistry.

Derives du benzothiophene

Karin M. Otte, Thomas A. Miller, J. Methot, 2006 .

A divergent approach to the synthesis of 3-substituted-2-pyrazolines: Suzuki cross-coupling of 3-sulfonyloxy-2-pyrazolines.

J. Grimm, D. Witter, Kevin J. Wilson, 2009, The Journal of organic chemistry.

Suppression of Racemization in the Carbonylation of Amino Acid-Derived Aryl Triflates.

J. Grimm, D. Witter, Kevin J. Wilson, 2007 .

Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met

P. Darke, S. Munshi, D. Hall, 2011, The Journal of Biological Chemistry.

Design of selective PI3Kδ inhibitors using an iterative scaffold-hopping workflow.

M. Augustin, M. Altman, X. Fradera, 2019, Bioorganic & medicinal chemistry letters.

A New Pyridazine Series of GABAA α5 Ligands

U. Gerhard, J. Atack, D. O'connor, 2005 .

Discovery of 1-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide (MK-8033): A Specific c-Met/Ron dual kinase inhibitor with preferential affinity for the activated state of c-Met.

Wei Lu, Michael D Altman, Craig Rosenstein, 2013, Journal of medicinal chemistry.

Discovery of a new series of PI3K-δ inhibitors from Virtual Screening.

M. Augustin, M. Altman, X. Fradera, 2021, Bioorganic & medicinal chemistry letters.

2,5-Disubstituted pyridines: the discovery of a novel series of 5-HT2A ligands.

D. O'connor, M. B. van Niel, A. Macleod, 2007, Bioorganic & medicinal chemistry letters.

2,5‐Disubstituted Pyridines: The Discovery of a Novel Series of 5‐HT2A Ligands.

D. O'connor, A. Macleod, Kevin J. Wilson, 2007 .

Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1).

J. Grimm, A. Kral, A. Szewczak, 2008, Bioorganic & medicinal chemistry letters.