A. Zvonok

发表

Metabolic Profiling of a CB2 Agonist, AM9338, Using LC-MS and Microcoil-NMR: Identification of a Novel Dihydroxy Adamantyl Metabolite

M. Malamas, A. Makriyannis, J. Wood, 2020, Frontiers in Pharmacology.

Differentiation between low- and high-efficacy CB1 receptor agonists using a drug discrimination protocol for rats

A. Makriyannis, J. Wood, S. Vadivel, 2013, Psychopharmacology.

Prophylactic cannabinoid administration blocks the development of paclitaxel-induced neuropathic nociception during analgesic treatment and following cessation of drug delivery

A. Hohmann, A. Makriyannis, G. Thakur, 2014, Molecular Pain.

Effects of a Selective Cannabinoid CB2 Agonist and Antagonist on Intravenous Nicotine Self Administration and Reinstatement of Nicotine Seeking

A. Makriyannis, S. Goldberg, B. Le Foll, 2012, PloS one.

Activation of cannabinoid CB2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation.

A. Hohmann, A. Makriyannis, A. Nackley, 2004, Journal of neurophysiology.

The cannabinoid CB2 receptor agonist AM1241 enhances neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis

E. Masliah, E. Rockenstein, A. Makriyannis, 2014, British journal of pharmacology.

Activation of peripheral cannabinoid CB1 and CB2 receptors suppresses the maintenance of inflammatory nociception: a comparative analysis

A. Hohmann, A. Makriyannis, J. Farthing, 2007, British journal of pharmacology.

Identification of a potent and highly efficacious, yet slowly desensitizing CB1 cannabinoid receptor agonist

K. Mackie, C. Chavkin, A. Makriyannis, 2004, British journal of pharmacology.

Selective Activation of Cannabinoid CB2 Receptors Suppresses Neuropathic Nociception Induced by Treatment with the Chemotherapeutic Agent Paclitaxel in Rats

A. Hohmann, A. Makriyannis, G. Thakur, 2008, Journal of Pharmacology and Experimental Therapeutics.

Ligand-binding architecture of human CB2 cannabinoid receptor: evidence for receptor subtype-specific binding motif and modeling GPCR activation.

Alexandros Makriyannis, Patricia H Reggio, David R Janero, 2008, Chemistry & biology.

Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor.

J. Deschamps, J. Flippen-Anderson, A. Makriyannis, 2005, Journal of Medicinal Chemistry.

[INCREMENT]9-Tetrahydrocannabinol discriminative stimulus effects of AM2201 and related aminoalkylindole analogs in rats

A. Makriyannis, T. Järbe, A. Zvonok, 2016, Behavioural pharmacology.

AM2389, a high-affinity, in vivo potent CB1-receptor-selective cannabinergic ligand as evidenced by drug discrimination in rats and hypothermia testing in mice

S. Nikas, A. Makriyannis, T. Järbe, 2012, Psychopharmacology.

Differentiation between low- and high-efficacy CB1 receptor agonists using a drug discrimination protocol for rats

A. Makriyannis, J. Wood, S. Vadivel, 2014, Psychopharmacology.

Therapeutic modulation of cannabinoid lipid signaling: metabolic profiling of a novel antinociceptive cannabinoid-2 receptor agonist.

A. Makriyannis, J. Wood, D. Janero, 2013, Life sciences.

Biochemical and Proteomic Characterization of Recombinant Human α/β Hydrolase Domain 6

A. Makriyannis, N. Zvonok, A. Zvonok, 2019, Scientific Reports.

The chemistry of azetidin-3-ones, oxetan-3-ones, and thietan-3-ones.

N. de Kimpe, A. Zvonok, Y. Dejaegher, 2002, Chemical reviews.

Synthesis and reactions of 5-hydroxy-4-oxo-3-arylpyrrolidino[1,2-b]pyrazoles

L. S. Stanishevskii, A. Zvonok, N. Kuz’menok, 1989 .

Reaction of carbonyl compounds with diazoalkanes as a method for epoxide synthesis. A review

A. Zvonok, E. Okaev, 1995 .

Synthesis and stereochemistry of α,β,α′,β′-diepoxy ketones

L. S. Stanishevskii, A. Zvonok, N. Kuz’menok, 1983 .

Synthesis and pharmacological properties of certain 3,4-dihydroxypiperidines

L. S. Stanishevskii, A. Zvonok, E. V. Yushkevich, 1990, Pharmaceutical Chemistry Journal.

Central mediation and differential blockade by cannabinergics of the discriminative stimulus effects of the cannabinoid CB1 receptor antagonist rimonabant in rats

A. Makriyannis, S. Vadivel, T. Järbe, 2011, Psychopharmacology.

Relation between the orientation of OH groups in stereoisomers of derivatives of 3,4-dioxy-1-methylpiperdine and their IR absorption

L. S. Stanishevskii, A. Zvonok, V. A. Mashenkov, 1982 .

Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS

D. Cockayne, J. H. Law, T. Vanderah, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Self-medication of a cannabinoid CB2 agonist in an animal model of neuropathic pain

J. Crystal, A. Hohmann, A. Makriyannis, 2011, PAIN.

Role of the Endogenous Cannabinoid System in Nicotine Addiction: Novel Insights

A. Makriyannis, S. Goldberg, B. Le Foll, 2015, Front. Psychiatry.

Immunofluorescent spectral analysis reveals the intrathecal cannabinoid agonist, AM1241, produces spinal anti-inflammatory cytokine responses in neuropathic rats exhibiting relief from allodynia

Ellen C. Dengler, A. Makriyannis, G. Thakur, 2012, Brain and behavior.

Pharmacological characterization of AM1710, a putative cannabinoid CB2 agonist from the cannabilactone class: Antinociception without central nervous system side-effects

A. Hohmann, A. Makriyannis, J. Wood, 2011, Pharmacology Biochemistry and Behavior.

Selective Activation of Cannabinoid CB2 Receptors Suppresses Hyperalgesia Evoked by Intradermal Capsaicin

A. Hohmann, A. Makriyannis, J. Farthing, 2004, Journal of Pharmacology and Experimental Therapeutics.

Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment.

M. Malamas, A. Makriyannis, J. Wood, 2019, Bioorganic & medicinal chemistry.

Design and Structure-Activity Relationships of Isothiocyanates as Potent and Selective N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibitors.

M. Malamas, A. Makriyannis, S. Pavlopoulos, 2021, Journal of medicinal chemistry.

Recyclization of 5-hydroxy-2-pyrazolines in the reaction with N-nucleophiles

A. Zvonok, N. Kuz’menok, T. A. Koval'chuk, 2008 .

Reaction between piperidine-4-spiro-2′-oxiranes and nucleophilic reagents

E. Okaev, A. Zvonok, 1993 .

Antinociceptive Effects of Racemic AM1241 and Its Chirally Synthesized Enantiomers: Lack of Dependence upon Opioid Receptor Activation

A. Hohmann, A. Makriyannis, E. Rahn, 2010, The AAPS Journal.