Mark Naples

发表

Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis.

K. Adeli, C. Cummins, K. Chien, 2016, Biochimica et biophysica acta.

Intestinal Insulin Resistance and Aberrant Production of Apolipoprotein B48 Lipoproteins in an Animal Model of Insulin Resistance and Metabolic Dyslipidemia

K. Adeli, Mark Naples, L. Federico, 2006, Diabetes.

GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance

Z. Pausova, K. Adeli, C. Bourdon, 2014, Molecular metabolism.

Insulin stimulates the expression of carbohydrate response element binding protein (ChREBP) by attenuating the repressive effect of Pit-1, Oct-1/Oct-2, and Unc-86 homeodomain protein octamer transcription factor-1.

T. Jin, Ling Liu, K. Adeli, 2009, Endocrinology.

Ezetimibe ameliorates intestinal chylomicron overproduction and improves glucose tolerance in a diet-induced hamster model of insulin resistance.

K. Adeli, M. Hussain, J. Iqbal, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Hepatocyte-specific Deletion of Janus Kinase 2 (JAK2) Protects against Diet-induced Steatohepatitis and Glucose Intolerance*

M. Woo, K. Wagner, K. Adeli, 2012, The Journal of Biological Chemistry.

Intestinal lipoprotein overproduction, a newly recognized component of insulin resistance, is ameliorated by the insulin sensitizer rosiglitazone: studies in the fructose-fed Syrian golden hamster.

G. Lewis, K. Adeli, K. Uffelman, 2005, Endocrinology.

Hepatic Cholesterol HomeostasisSignificance

R. S. Kiss, K. Adeli, Cheng-I J. Ma, 2013 .

Hepatic Cholesterol Homeostasis: Is the Low-Density Lipoprotein Pathway a Regulatory or a Shunt Pathway?

R. S. Kiss, K. Adeli, Cheng-I J. Ma, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Hepatic lipase mRNA, protein, and plasma enzyme activity is increased in the insulin-resistant, fructose-fed Syrian golden hamster and is partially normalized by the insulin sensitizer rosiglitazone.

G. Lewis, K. Adeli, J. Brunzell, 2004, Diabetes.

Glycine Normalizes Hepatic Triglyceride-Rich VLDL Secretion by Triggering the CNS in High-Fat Fed Rats

K. Adeli, J. Yue, T. Lam, 2012, Circulation research.

Intestinal lipoprotein production is stimulated by an acute elevation of plasma free fatty acids in the fasting state: studies in insulin-resistant and insulin-sensitized Syrian golden hamsters.

G. Lewis, K. Adeli, K. Uffelman, 2004, Endocrinology.

Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production.

K. Adeli, Q. Su, W. Qiu, 2009, American journal of physiology. Gastrointestinal and liver physiology.

LCAT-null mice develop improved hepatic insulin sensitivity through altered regulation of transcription factors and suppressors of cytokine signaling.

K. Adeli, D. Ng, Hui Song, 2007, American journal of physiology. Endocrinology and metabolism.

Metabolic effects of dietary cholesterol in an animal model of insulin resistance and hepatic steatosis.

M. Wheeler, K. Adeli, Q. Su, 2009, American journal of physiology. Endocrinology and metabolism.

Role of MicroRNAs in Translational Control of the Human Apolipoprotein B100 mRNA

K. Adeli, M. Dekker, Sarah Farr, 2013 .

Lecithin:Cholesterol Acyltransferase Deficiency Protects against Cholesterol-induced Hepatic Endoplasmic Reticulum Stress in Mice*

K. Adeli, M. Hossain, P. Connelly, 2012, The Journal of Biological Chemistry.

in Subpostremal NTS Neurons Glycine Binding Site of the Synaptic NMDA Receptor

R. Ritter, K. Adeli, M. Covasa, 2015 .

Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage

B. Alman, K. Adeli, H. Whetstone, 2015, Arthritis & rheumatology.

Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: evidence for the role of sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction.

K. Adeli, M. Dekker, W. Qiu, 2013, Atherosclerosis.

Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: evidence for statin-induced hepatic insulin sensitization.

K. Adeli, E. Xu, Mark Naples, 2008, Atherosclerosis.

C‐reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: Role of mitogen‐activated protein kinases

K. Adeli, C. Xiao, L. Xi, 2011, Hepatology.

Hepatic mitochondrial and ER stress induced by defective PPARα signaling in the pathogenesis of hepatic steatosis.

K. Adeli, Kezhong Zhang, M. Santha, 2014, American journal of physiology. Endocrinology and metabolism.

Rosiglitazone improves intestinal lipoprotein overproduction in the fat-fed Syrian Golden hamster, an animal model of nutritionally-induced insulin resistance.

G. Lewis, K. Adeli, K. Uffelman, 2004, Atherosclerosis.

AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism[S]

Khosrow Adeli, Sergey Filippov, K. Adeli, 2013, Journal of Lipid Research.

Central Nervous System Regulation of Intestinal Lipoprotein Metabolism by Glucagon-Like Peptide-1 via a Brain–Gut Axis

K. Adeli, J. Iqbal, M. Hussain, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B–containing lipoproteins

A. Suzuki, K. Adeli, J. Iqbal, 2008, Hepatology.

Hepatic PTP-1B expression regulates the assembly and secretion of apolipoprotein B-containing lipoproteins: evidence from protein tyrosine phosphatase-1B overexpression, knockout, and RNAi studies.

Crystal S Au, M. Tremblay, G. Lewis, 2004, Diabetes.

Molecular Determinants of High Affinity Binding to Group III Metabotropic Glutamate Receptors*

D. Hampson, H. Thøgersen, Erica Rosemond, 2002, The Journal of Biological Chemistry.

Pharmacological profiles of the metabotropic glutamate receptor ligands [3H]L-AP4 and [3H]CPPG

D. Hampson, Mark Naples, 2001, Neuropharmacology.

Effect of rosuvastatin on hepatic production of apolipoprotein B-containing lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia.

K. Adeli, Taryne M. Chong, Graham J Smith, 2006, Atherosclerosis.

LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins.

K. Adeli, Mark Naples, Christopher Baker, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Oleate-mediated stimulation of microsomal triglyceride transfer protein (MTP) gene promoter: implications for hepatic MTP overexpression in insulin resistance.

K. Adeli, R. Sato, C. Taghibiglou, 2005, Biochemistry.

Lecithin:Cholesterol Acyltransferase Deficiency Protects against Cholesterol-induced Hepatic Endoplasmic Reticulum Stress in Mice*

K. Adeli, P. Connelly, C. Cummins, 2012, The Journal of Biological Chemistry.

LXR (cid:1) activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins

K. Adeli, Mark Naples, Abigale Miller, 2009 .

LXR (cid:1) activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins

K. Adeli, Mark Naples, Abigale Miller, 2009 .

Integrative Physiology Glycine Normalizes Hepatic Triglyceride-rich Vldl Secretion by Triggering the Cns in High-fat Fed Rats Methods and Results: Using 10-hour Fasted Male Sprague-dawley Rats Implanted with Stereotaxic Cannulae into an Extrahypothalamic Region Termed the Dorsal Vagal Complex (dvc)

K. Adeli, J. Yue, Mark Naples, 2022 .

Glycine Normalizes Hepatic Triglyceride-Rich VLDL Secretion by Triggering the CNS in High-Fat Fed Rats

K. Adeli, J. Yue, T. Lam, 2012, Circulation research.

Ezetimibe ameliorates intestinal chylomicron overproduction and improves glucose tolerance in a diet-induced hamster model of insulin resistance.

K. Adeli, J. Iqbal, Mark Naples, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Ezetimibe Ameliorates Intestinal Chylomicron Overproduction and Improves Glucose

K. Adeli, J. Iqbal, Mark Naples, 2012 .