C. Frederick

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The Histopathological and Biochemical Response of the Stomach of Male F344/N Rats Following Two Weeks of Oral Dosing with Ethyl Acrylate

J. Frantz, C. Frederick, G. A. Hazelton, 1990, Toxicologic pathology.

Preparation and solid-state properties of cesium triiodovanadate, cesium triiodochromate, and cesium triiodimanganate

G. McPherson, C. Frederick, L. Sindel, 1975 .

Safety assessment of drug metabolites: implications of regulatory guidance and potential application of genetically engineered mouse models that express human P450s.

F. Sistare, J. Degeorge, M. Powley, 2009, Chemical research in toxicology.

Genotoxicity in the rodent urinary bladder.

N. Gorelick, C. King, C. Frederick, 1995, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Cytochrome P-450-and Flavin-containing Monooxygenase-catalyzed Formation of the Carcinogen A /-Hydroxy-2-aminofluorene and Its Covalent Binding to Nuclear DMA 1

F. Guengerich, F. Kadlubar, D. Ziegler, 2006 .

Rate and route of oxidation of acrylic acid to carbon dioxide in rat liver.

L. Finch, C. Frederick, 1992, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Cytochrome P-450- and flavin-containing monooxygenase-catalyzed formation of the carcinogen N-hydroxy-2-aminofluorene and its covalent binding to nuclear DNA.

F. Guengerich, F. Kadlubar, D. Ziegler, 1982, Cancer research.

Production and isolation of siderophores from the soil fungus Epicoccum purpurascens.

M. Bentley, P. J. Szaniszlo, W. Shive, 1981, Biochemistry.

Evidence for estradiol promotion of neoplastic lesions in the rat vagina after initiation with N-methyl-N-nitrosourea.

J. E. Heath, W. Branham, D. Sheehan, 1982, Carcinogenesis.

The structure of the fungal siderophore, isotriornicin.

M. Bentley, W. Shive, C. Frederick, 1982, Biochemical and biophysical research communications.

Structure of triornicin, a new siderophore.

M. Bentley, W. Shive, C. Frederick, 1981, Biochemistry.

A hybrid computational fluid dynamics and physiologically based pharmacokinetic model for comparison of predicted tissue concentrations of acrylic acid and other vapors in the rat and human nasal cavities following inhalation exposure.

C B Frederick, K T Morgan, R P Subramaniam, 2001, Inhalation toxicology.

Application of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry extrapolation of acidic vapors in the upper airways.

C B Frederick, K T Morgan, R P Subramaniam, 1998, Toxicology and applied pharmacology.

The regional hydrolysis of ethyl acrylate to acrylic acid in the rat nasal cavity.

L. Finch, C. Frederick, J. Udinsky, 1994, Toxicology letters.

Implementation of EPA Revised Cancer Assessment Guidelines: Incorporation of Mechanistic and Pharmacokinetic Data.

H J Clewell, M E Andersen, C B Frederick, 1997, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Skin irritation, basal epithelial cell proliferation, and carcinogenicity evaluations of a representative specialty acrylate and methacrylate.

R. Garman, S. Hermansky, J. Mirsalis, 2003, Regulatory toxicology and pharmacology : RTP.

Physiologically based pharmacokinetic (PBPK) models for nasal tissue dosimetry of organic esters: assessing the state-of-knowledge and risk assessment applications with methyl methacrylate and vinyl acetate.

Melvin E Andersen, Trevor Green, M. Andersen, 2002, Regulatory toxicology and pharmacology : RTP.

Use of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry comparisons of ester vapors.

Julia S Kimbell, Ravi P Subramaniam, K. Morgan, 2002, Toxicology and applied pharmacology.

Prostaglandin endoperoxide synthetase-mediated metabolism of carcinogenic aromatic amines and their binding to DNA and protein.

F. Kadlubar, T. Zenser, C. Weis, 1982, Biochemical and biophysical research communications.

A CFD-PBPK hybrid model for simulating gas and vapor uptake in the rat nose.

J. Ultman, J. Kimbell, C. Frederick, 1998, Toxicology and applied pharmacology.

Hepatic N-oxidation, acetyl-transfer and DNA-binding of the acetylated metabolites of the carcinogen, benzidine.

F. Kadlubar, T. Flammang, C. Weis, 1985, Carcinogenesis.

The effect of lifetime sodium saccharin dosing on mice initiated with the carcinogen 2-acetylaminofluorene.

R. Kodell, F. Kadlubar, W. Sheldon, 1989, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Lessons learned in applying the U.S. EPA proposed cancer guidelines to specific compounds.

M E Meek, M E Andersen, G A Boorman, 2000, Toxicological sciences : an official journal of the Society of Toxicology.

Metabolites in Safety Testing: “MIST” for the Clinical Pharmacologist

R. Obach, C. Frederick, 2010, Clinical pharmacology and therapeutics.

A physiologically based pharmacokinetic and pharmacodynamic model to describe the oral dosing of rats with ethyl acrylate and its implications for risk assessment.

D W Potter, M E Andersen, C B Frederick, 1992, Toxicology and applied pharmacology.

Limiting the uncertainty in risk assessment by the development of physiologically based pharmacokinetic and pharmacodynamic models.

C B Frederick, C. Frederick, 1993, Toxicology letters.

The disposition and metabolism of acrylic acid and ethyl acrylate in male Sprague-Dawley rats

J. D. Debethizy, C. Frederick, H. Scribner, 1987 .

Upper Respiratory Tract Uptake of Acrylate Ester and Acid Vapors

John B. Morris, C. Frederick, 1995 .

The disposition and metabolism of acrylic acid and ethyl acrylate in male Sprague-Dawley rats.

J. D. Debethizy, C. Frederick, H. Scribner, 1987, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Application of a hybrid CFD-PBPK nasal dosimetry model in an inhalation risk assessment: an example with acrylic acid.

C B Frederick, M. Andersen, H. Clewell, 2000, Toxicological sciences : an official journal of the Society of Toxicology.

Dosimetric adjustment factors for methyl methacrylate derived from a steady-state analysis of a physiologically based clearance-extraction model.

M E Andersen, C B Frederick, M. Andersen, 1999, Inhalation toxicology.

Metabolism of acrylic acid to carbon dioxide in mouse tissues.

K. Black, L. Finch, C. Frederick, 1993, Fundamental and applied toxicology : official journal of the Society of Toxicology.

U.S. Environmental Protection Agency's revised cancer guidelines for carcinogen risk assessment.

Y. Dragan, D. Brusick, M. Andersen, 1998, Toxicology and applied pharmacology.

Improving Risk Assessment: Toxicological Research Needs

Paul Foster, Roger O. McClellan, Kevin Morgan, 2002 .

Improving Risk Assessment : Toxicological Research Needs 1

R. McClellan, R. Melnick, L. Haber, 2003 .

Applying simulation modeling to problems in toxicology and risk assessment--a short perspective.

H J Clewell, M E Andersen, C B Frederick, 1995, Toxicology and applied pharmacology.

Spectroscopic Studies of the Structures of Butyl and Bromobutyl Rubbers

A. Dekmezian, C. Frederick, D. M. Cheng, 1990 .

Induction of the mitochondrial permeability transition in vitro by short-chain carboxylic acids.

C. Palmeira, K. Wallace, C. Frederick, 2000, Biochemical and Biophysical Research Communications - BBRC.

Regional Histopathology of The Mouse Nasal Cavity Following Two Weeks of Exposure to Acrylic Acid for Either 6 or 22 Hours Per Day

L. Lomax, C. Frederick, David W. Brown, 1994, Inhalation Toxicology.

Letter to the EditorLETTERS TO THE EDITOR: To the Editor:

Y. Dragan, D. Brusick, M. Andersen, 1998 .

Lessons learned in applying the U.S. EPA proposed cancer guidelines to specific compounds.

M. E. Meek, Y. Dragan, D. Brusick, 2000, Toxicological sciences : an official journal of the Society of Toxicology.