Rajlakshmi Marpakwar

Inhibition of group-I metabotropic glutamate receptors protects against prion toxicity

S. Hornemann, A. Aguzzi, F. Gasparini, 2017, PLoS pathogens.

The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6

S. Hornemann, A. Aguzzi, K. Monk, 2016, Nature.

Loss of PIKfyve drives the spongiform degeneration in prion diseases

A. Aguzzi, K. Frontzek, M. Losa, 2021, bioRxiv.

MP0533: A Multispecific Darpin CD3 Engager Targeting CD33, CD123, and CD70 for the Treatment of AML and MDS Designed to Selectively Target Leukemic Stem Cells

D. Steiner, V. Kirkin, M. Hänggi, 2022, Blood.