Yanxia Li

发表

Design, synthesis, and biological evaluation of hydroxamic acid-substituted 2,4-diaryl aminopyrimidines as potent EGFRT790M/L858R inhibitors for the treatment of NSCLC.

Xiaodong Ma, Y. Qi, Q. Meng, 2021, Bioorganic chemistry.

Design, synthesis, and biological evaluation of cyano-substituted 2,4-diarylaminopyrimidines as potent JAK3 inhibitors for the treatment of B-cell lymphoma.

Xiaodong Ma, Yue Jin, Bin Wu, 2021, Bioorganic chemistry.

Structural optimization of diphenylpyrimidine scaffold as potent and selective epidermal growth factor receptor inhibitors against L858R/T790M resistance mutation in nonsmall cell lung cancer

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Chemical biology & drug design.

Design and synthesis of sulfonamide-substituted diphenylpyrimidines (SFA-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B-cell lymphoblastic leukemia.

Jinyong Peng, Xiaodong Ma, Li-na Xu, 2017, European journal of medicinal chemistry.

Structural optimization of diphenylpyrimidine derivatives (DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B leukemia cell lines.

Jinyong Peng, Xiaodong Ma, Zhihao Liu, 2017, European journal of medicinal chemistry.

Novel Pyrimidines as Multitarget Protein Tyrosine Kinase Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Bo Sun, Huijun Sun, Xiaodong Ma, 2019, ChemMedChem.

Covalent binding design strategy: A prospective method for discovery of potent targeted anticancer agents.

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2017, European journal of medicinal chemistry.

Synthesis and biological evaluation of morpholine-substituted diphenylpyrimidine derivatives (Mor-DPPYs) as potent EGFR T790M inhibitors with improved activity toward the gefitinib-resistant non-small cell lung cancers (NSCLC).

Xiaodong Ma, Q. Meng, Changyuan Wang, 2017, European journal of medicinal chemistry.

Novel 4-anilinoquinazoline derivatives featuring an 1-adamantyl moiety as potent EGFR inhibitors with enhanced activity against NSCLC cell lines.

Xiaodong Ma, Yue Jin, Xu Han, 2016, European journal of medicinal chemistry.

Synthesis and biological evaluation of azole-diphenylpyrimidine derivatives (AzDPPYs) as potent T790M mutant form of epidermal growth factor receptor inhibitors.

Jinyong Peng, Xiaodong Ma, Yue Jin, 2016, Bioorganic & medicinal chemistry.

New acrylamide-substituted quinazoline derivatives with enhanced potency for the treatment of EGFR T790M-mutant non-small-cell lung cancers.

Wenjuan Liu, Xiaodong Ma, Zhihao Liu, 2018, Bioorganic chemistry.

Novel Selective and Potent EGFR Inhibitor that Overcomes T790M-Mediated Resistance in Non-Small Cell Lung Cancer

Xiaodong Ma, Yue Jin, Zeyao Tang, 2016, Molecules.

Design and synthesis of diphenylpyrimidine derivatives (DPPYs) as potential dual EGFR T790M and FAK inhibitors against a diverse range of cancer cell lines.

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2019, Bioorganic chemistry.

Design and synthesis of phosphoryl-substituted diphenylpyrimidines (Pho-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors: Targeted treatment of B lymphoblastic leukemia cell lines.

Huijun Sun, Xiaodong Ma, Q. Meng, 2017, Bioorganic & medicinal chemistry.

Discovery of Novel Bruton's Tyrosine Kinase (BTK) Inhibitors Bearing a N,9-Diphenyl-9H-purin-2-amine Scaffold.

Xiaodong Ma, Changyuan Wang, Jinyong Peng, 2016, ACS medicinal chemistry letters.

Phosphamide-containing diphenylpyrimidine analogues (PA-DPPYs) as potent focal adhesion kinase (FAK) inhibitors with enhanced activity against pancreatic cancer cell lines.

Xiaodong Ma, Bin Wu, Changyuan Wang, 2017, Bioorganic & medicinal chemistry.

C-2 (E)-4-(Styryl)aniline substituted diphenylpyrimidine derivatives (Sty-DPPYs) as specific kinase inhibitors targeting clinical resistance related EGFRT790M mutant.

Jinyong Peng, Xiaodong Ma, Q. Meng, 2017, Bioorganic & medicinal chemistry.

Ultrasonic Elastography of the Rectus Femoris, a Potential Tool to Predict Sarcopenia in Patients With Chronic Obstructive Pulmonary Disease

Qiuyue Wang, Gang Hou, Yan Yin, 2022, Frontiers in Physiology.

Analysis of the bacterial community in chronic obstructive pulmonary disease sputum samples by denaturing gradient gel electrophoresis and real-time PCR

Y. Xin, Xin Lu, Yanxia Li, 2014, BMC Pulmonary Medicine.

Design, synthesis and activity evaluation of isopropylsulfonyl-substituted 2,4- diarylaminopyrimidine derivatives as FAK inhibitors for the potential treatment of pancreatic cancer.

Xiaodong Ma, Changyuan Wang, Xu Zheng, 2022, European journal of medicinal chemistry.