E. Miller

发表

Metabolism of a serotonin-4 receptor partial agonist 4-{4-[4-tetrahydrofuran-3-yloxy)-benzo[d]isoxazol-3-yloxymethyl]-piperidin-1-ylmethyl}-tetrahydropyran-4-ol (TBPT): identification of an unusual pharmacologically active cyclized oxazolidine metabolite in human.

G. S. Walker, R. Obach, J. W. Wong, 2013, Journal of pharmaceutical sciences.

High specificity in response of the sodium-dependent multivitamin transporter to derivatives of pantothenic acid.

M. G. Finn, M. Varma, R. L. Dow, 2013, Current topics in medicinal chemistry.

Phenotyping hepatocellular metabolism using uniformly labeled carbon-13 molecular probes and LC-HRMS stable isotope tracing.

J. Meissen, R. Steenwyk, Min Wan, 2016, Analytical biochemistry.

Understanding the clinical pharmacokinetics of a GABAA partial agonist by application of in vitro tools

D. B. Duignan, F. Nelson, R. Obach, 2010, Xenobiotica; the fate of foreign compounds in biological systems.

Pharmacological Characterization of 2-Methyl- N -((2 (cid:1) -(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for (cid:1) -Opioid Receptors □ S

Anne W. Schmidt, P. Verhoest, S. Grimwood, 2011 .

Discovery and preclinical characterization of 1-methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1H-pyrazolo-[3,4-b]pyrazine (PF470): a highly potent, selective, and efficacious metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator.

J. Cianfrogna, A. Stepan, Daniel P. Walker, 2014, Journal of medicinal chemistry.

Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors

Anne W. Schmidt, P. Verhoest, J. McLaughlin, 2011, Journal of Pharmacology and Experimental Therapeutics.

Metabolism-directed design of oxetane-containing arylsulfonamide derivatives as γ-secretase inhibitors.

L. Pustilnik, A. Stepan, R. Obach, 2011, Journal of medicinal chemistry.

The 5-Hydroxytryptamine4 Receptor Agonists Prucalopride and PRX-03140 Increase Acetylcholine and Histamine Levels in the Rat Prefrontal Cortex and the Power of Stimulated Hippocampal θ Oscillations

M. Hajós, Robin T. Nelson, S. Grimwood, 2012, Journal of Pharmacology and Experimental Therapeutics.

Discovery and Characterization of (R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman Primates.

J. Cianfrogna, A. Stepan, Daniel P. Walker, 2017, Journal of medicinal chemistry.

Quantitative PK–PD Model-Based Translational Pharmacology of a Novel Kappa Opioid Receptor Antagonist Between Rats and Humans

Yifeng Lu, Cheng Chang, Wonkyung Byon, 2011, The AAPS Journal.

Highly Potent , Selective , and E ffi cacious Metabotropic Glutamate Receptor 5 ( mGluR 5 ) Negative Allosteric Modulator

Ey, J. Cianfrogna, A. Stepan, 2014 .