S. Obeng

发表

In vitro and in vivo functional profile characterization of 17‐cyclopropylmethyl‐3,14&bgr;‐dihydroxy‐4,5&agr;‐epoxy‐6&agr;‐(isoquinoline‐3‐carboxamido)morphinan (NAQ) as a low efficacy mu opioid receptor modulator

D. Selley, Yunyun Yuan, Yan Zhang, 2018, European journal of pharmacology.

Interactive Effects of µ-Opioid and Adrenergic-α2 Receptor Agonists in Rats: Pharmacological Investigation of the Primary Kratom Alkaloid Mitragynine and Its Metabolite 7-Hydroxymitragynine

P. Soto, J. Wilkerson, T. Hiranita, 2022, The Journal of Pharmacology and Experimental Therapeutics.

Activity of Mitragyna speciosa ("Kratom") Alkaloids at Serotonin Receptors.

C. McCurdy, Clinton E. Canal, T. Hiranita, 2021, Journal of medicinal chemistry.

Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats

Tobias Braun, J. Wilkerson, J. Fortner, 2020, The Journal of Pharmacology and Experimental Therapeutics.

Preclinical Characterization and Development on NAQ as a Mu Opioid Receptor Partial Agonist for Opioid Use Disorder Treatment.

Boshi Huang, K. Nicholson, M. Banks, 2022, ACS pharmacology & translational science.

Antinociceptive Interactions between the Imidazoline I2 Receptor Agonist 2-BFI and Opioids in Rats: Role of Efficacy at the μ-Opioid Receptor

J. Siemian, Jun-Xu Li, Yanan Zhang, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists.

Boshi Huang, D. Selley, W. Dewey, 2022, Journal of medicinal chemistry.

Role of mu‐opioid agonist efficacy on antinociceptive interactions between mu agonists and the nociceptin opioid peptide agonist Ro 64‐6198 in rhesus monkeys

K. Rice, M. Banks, J. Cornelissen, 2019, European journal of pharmacology.

Women's Voices in Akan Juridical Discourse

Beverly J. Stoeltje, S. Obeng, 2002 .

Application of Bivalent Bioisostere Concept on Design and Discovery of Potent Opioid Receptor Modulators.

D. Selley, W. Dewey, Hongguang Ma, 2019, Journal of medicinal chemistry.

Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys

K. Rice, S. Negus, M. Banks, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Effectiveness comparisons of G-protein biased and unbiased mu opioid receptor ligands in warm water tail-withdrawal and drug discrimination in male and female rats

K. Rice, B. Blough, S. Negus, 2019, Neuropharmacology.

Characterization of 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-carboxamido)morphinan (NAN) as a Novel Opioid Receptor Modulator for Opioid Use Disorder Treatment.

D. Selley, Chongguang Chen, L. Liu-Chen, 2019, ACS chemical neuroscience.

Structure-Activity Relationship Studies of 6α- and 6β-Indolylacetamidonaltrexamine Derivatives as Bitopic Mu Opioid Receptor Modulators and Elaboration of the "Message-Address Concept" To Comprehend Their Functional Conversion.

D. Selley, W. Dewey, H. Akbarali, 2018, ACS chemical neuroscience.

Novel Approaches, Drug Candidates, and Targets in Pain Drug Discovery.

C. McCurdy, F. León, T. Hiranita, 2021, Journal of medicinal chemistry.

Slow conformational dynamics of the human A2A adenosine receptor are temporally ordered

H. Gutiérrez‐de‐Terán, M. Eddy, C. McCurdy, 2021, Structure.

The effects of mitragynine and morphine on schedule-controlled responding and antinociception in rats

B. Avery, J. Wilkerson, C. McCurdy, 2019, Psychopharmacology.

Design, Synthesis, and Biological Evaluation of the Third Generation 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'-pyridyl)carboxamido]morphinan (NAP) Derivatives as μ/κ Opioid Receptor Dual Selective Ligands.

D. Selley, W. Dewey, H. Akbarali, 2019, Journal of medicinal chemistry.

Studies on diketopiperazine and dipeptide analogs as opioid receptor ligands.

V. Neugebauer, T. Abbruscato, C. McCurdy, 2023, European journal of medicinal chemistry.

Investigation of the Adrenergic and Opioid Binding affinities, Metabolic Stability, Plasma Protein Binding Properties and Functional Effects of Selected Indole-based Kratom Alkaloids.

B. Avery, S. Ramanathan, C. McCurdy, 2019, Journal of medicinal chemistry.

The effects of mitragynine and morphine on schedule-controlled responding and antinociception in rats

B. Avery, J. Wilkerson, C. McCurdy, 2019, Psychopharmacology.

The Adrenergic a2 Receptor‐Mediated Discriminative‐Stimulus Effects of Mitragynine, the Primary Alkaloid in Kratom (Mitragyna Speciosa) in Rats

T. Hiranita, L. McMahon, M. Behnke, 2020, The FASEB Journal.

Potential Contribution of 7‐Hydroxymitragynine, a Metabolite of the Primary Kratom (Mitragyna Speciosa) Alkaloid Mitragynine, to the μ‐Opioid Activity of Mitragynine in Rats

T. Hiranita, Abhisheak Sharma, L. McMahon, 2020, The FASEB Journal.

In Vitro and In Vivo Pharmacological Comparison of Mu‐Opioid Receptor Activity of the Kratom (Mitragyna speciosa) Alkaloid Mitragynine and its Metabolite 7‐Hydroxymitragynine

C. McCurdy, T. Hiranita, L. McMahon, 2021, Alzheimer's & Dementia.

In vitro and in vivo pharmacology of kratom.

J. Wilkerson, C. McCurdy, T. Hiranita, 2022, Advances in pharmacology.

Methylation Products of 6β- N-Heterocyclic Substituted Naltrexamine Derivatives as Potential Peripheral Opioid Receptor Modulators.

D. Selley, W. Dewey, H. Akbarali, 2018, ACS chemical neuroscience.

Kappa opioid receptors mediate an initial aversive component of paclitaxel-induced neuropathy

D. Selley, W. Toma, M. Damaj, 2020, Psychopharmacology.

Pharmacological characterization of 17-cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-6-[(3'-fluoro-4'-pyridyl)acetamido]morphinan (NFP) as a dual selective MOR/KOR ligand with potential applications in treating opioid use disorder.

Bethany A. Reinecke, D. Selley, Chongguang Chen, 2019, European journal of pharmacology.

Anionic Phospholipids Control Mechanisms of GPCR-G Protein Recognition

K. Jacobson, Zhang-Guo Gao, M. Eddy, 2023, bioRxiv.

Molecular and behavioral mechanisms mediating paclitaxel‐induced changes in affect‐like behavior in mice

D. Selley, D. Bagdas, W. Toma, 2019, The FASEB Journal.

Correction to "Novel Approaches, Drug Candidates, and Targets in Pain Drug Discovery".

C. McCurdy, T. Hiranita, L. McMahon, 2021, Journal of medicinal chemistry.