Peng Yin

发表

Cerebellum-enriched protein INPP5A contributes to selective neuropathology in mouse model of spinocerebellar ataxias type 17

B. Tang, Shihua Li, Xiao-Jiang Li, 2020, Nature Communications.

CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys

T. Jiang, Zhengyi Yang, C. Qin, 2019, Cell Research.

PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis

Shihua Li, Xiao-Jiang Li, L. Liao, 2021, Protein & cell.

MANF regulates hypothalamic control of food intake and body weight

Shihua Li, Shanshan Huang, Su Yang, 2017, Nature Communications.

Brain Region- and Age-Dependent 5-Hydroxymethylcytosine Activity in the Non-Human Primate

L. Xie, Shihua Li, Xiao-Jiang Li, 2022, Frontiers in Aging Neuroscience.

Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins

Shihua Li, Xiao-Jiang Li, Peng Yin, 2017, Proceedings of the National Academy of Sciences.

PRRT2 frameshift mutation reduces its mRNA stability resulting loss of function in paroxysmal kinesigenic dyskinesia.

L. Mei, B. Tang, W. Xiong, 2019, Biochemical and biophysical research communications.

SQSTM1-mediated clearance of cytoplasmic mutant TARDBP/TDP-43 in the monkey brain

Shihua Li, Xiao-Jiang Li, Jiye Ye, 2021, Autophagy.

Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains

Ting Zhao, Shihua Li, Xiao-Jiang Li, 2019, Acta Neuropathologica.

Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains

Yan Zeng, Shihua Li, Sen Yan, 2022, Cellular and Molecular Life Sciences.

New pathogenic insights from large animal models of neurodegenerative diseases

Shihua Li, Xiao-Jiang Li, Weili Yang, 2022, Protein & Cell.

Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2015, Molecular Neurodegeneration.

Huntingtin-Associated Protein 1 in Mouse Hypothalamus Stabilizes Glucocorticoid Receptor in Stress Response

Xingshun Xu, Shihua Li, Xiao-Jiang Li, 2020, Frontiers in Cellular Neuroscience.

CHD8 mutations increase gliogenesis to enlarge brain size in the nonhuman primate

Zhengyi Yang, Shihua Li, Zhiguang Zhao, 2023, Cell Discovery.

Author Correction: Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form

Zhaohui S. Qin, Z. Qin, B. Tang, 2020, Nature Communications.

Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form

Zhaohui S. Qin, Z. Qin, Shihua Li, 2020, Nature Communications.

Cerebellum-enriched protein INPP5A contributes to selective neuropathology in mouse model of spinocerebellar ataxias type 17

B. Tang, Shihua Li, Xiao-Jiang Li, 2020, Nature Communications.

Neuroinflammation in Huntington’s disease: From animal models to clinical therapeutics

Shihua Li, Xiao-Jiang Li, Peng Yin, 2022, Frontiers in Immunology.

PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis

Shihua Li, L. Liao, Sen Yan, 2021, Protein & Cell.

Aged monkey brains reveal the role of ubiquitin-conjugating enzyme UBE2N in the synaptosomal accumulation of mutant huntingtin.

Shihua Li, Xiao-Jiang Li, Xiahe Huang, 2015, Human molecular genetics.

Lack of association of somatic CAG repeat expansion with striatal neurodegeneration in HD knock-in animal models.

Shihua Li, Xiao-Jiang Li, Sen Yan, 2021, Human molecular genetics.

Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease

Shihua Li, Xiao-Jiang Li, Su Yang, 2020, EMBO reports.

Mutant Alpha-Synuclein Causes Age-Dependent Neuropathology in Monkey Brain

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2015, The Journal of Neuroscience.

Loss of TDP-43 promotes somatic CAG repeat expansion in Huntington’s disease knock-in mice

Xuezhi Duan, Shihua Li, Xiao-Jiang Li, 2023, Progress in Neurobiology.

Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains

Yan Zeng, Shihua Li, Sen Yan, 2022, Cellular and Molecular Life Sciences.

Pathological insights from amyotrophic lateral sclerosis animal models: comparisons, limitations, and challenges

Shihua Li, Peng Yin, Xiao-Jiang Li, 2023, Translational Neurodegeneration.

Aged monkey brains reveal the role of ubiquitin-conjugating enzyme UBE2N in the synaptosomal accumulation of mutant huntingtin.

Shihua Li, Xiao-Jiang Li, Xiahe Huang, 2015, Human molecular genetics.

Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins

Shihua Li, Xiao-Jiang Li, Peng Yin, 2017, Proceedings of the National Academy of Sciences.

Cytoplasmic TDP-43 impairs the activity of the ubiquitin-proteasome system

Shihua Li, Xiao-Jiang Li, Peng Yin, 2021, Experimental Neurology.

Pathogenic TDP-43 accelerates the generation of toxic exon1 HTT in Huntington's disease knock-in mice.

Su Yang, Peng Yin, Fuyu Deng, 2024, Aging cell.

Pathologic TDP-43 downregulates myelin gene expression in the monkey brain.

Sen Yan, Peng Yin, Xiao-Jiang Li, 2024, Brain pathology.

Loss of TDP-43 mediates severe neurotoxicity by suppressing PJA1 gene transcription in the monkey brain

Shihua Li, Peng Yin, Fuyu Deng, 2024, Cellular and molecular life sciences : CMLS.

Comparing HD knockin pigs and mice reveals the pathological role of IL-17.

Shihua Li, Sen Yan, Peng Yin, 2023, Cell reports.

HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington’s disease mice

Su Yang, Peng Yin, Laiqiang Chen, 2024, Cell death & disease.