M. G. Mancini

发表

Defining estrogenic mechanisms of bisphenol A analogs through high throughput microscopy-based contextual assays.

Fabio Stossi, Michael J. Bolt, Jane E Lamerdin, 2014, Chemistry & biology.

Endocrine disrupting chemicals differentially alter intranuclear dynamics and transcriptional activation of estrogen receptor-α

Michael J. Bolt, Adam T. Szafran, F. Stossi, 2021, iScience.

Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms

Adam T. Szafran, F. Stossi, E. Pistikopoulos, 2020, PLoS Comput. Biol..

Systems level-based RNAi screening by high content analysis identifies UBR5 as a regulator of estrogen receptor-α protein levels and activity

Michael J. Bolt, F. Stossi, M. Mancini, 2014, Oncogene.

Use of HCA in subproteome-immunization and screening of hybridoma supernatants to define distinct antibody binding patterns.

Adam T. Szafran, D. Edwards, J. Nickerson, 2016, Methods.

Differential Phosphorylation of Perilipin 1A at the Initiation of Lipolysis Revealed by Novel Monoclonal Antibodies and High Content Analysis

D. Edwards, Sean M. Hartig, J. Price, 2013, PloS one.

Single Cell Analysis Of Transcriptionally Active Alleles By Single Molecule FISH.

F. Stossi, M. Mancini, Ragini M. Mistry, 2020, Journal of visualized experiments : JoVE.

Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1.

M. Mancini, D. Stenoien, E. Allegretto, 2000, Molecular endocrinology.

Erratum: Estrogen-receptor-α exchange and chromatin dynamics are ligand- and domain-independent (J. Cell Sci. vol. 119 (4101-4116))

Adam T. Szafran, D. Ingber, Z. D. Sharp, 2006 .

Inactivating Pit‐1 mutations alter subnuclear dynamics suggesting a protein misfolding and nuclear stress response

Z. D. Sharp, M. Mancini, D. Stenoien, 2004, Journal of cellular biochemistry.

Erratum: A c619y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1) (Molecular Endocrinology (1999) 13 (2065-2075))

D. Edwards, L. Nazareth, D. Lamb, 2000 .

High‐Content Screening Identifies Src Family Kinases as Potential Regulators of AR‐V7 Expression and Androgen‐Independent Cell Growth

Adam T. Szafran, M. Marcelli, M. Mancini, 2017, The Prostate.

Sensitive image-based chromatin binding assays using inducible ERα to rapidly characterize estrogenic chemicals and mixtures

Adam T. Szafran, F. Stossi, M. Mancini, 2022, iScience.

Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity

F. Stossi, R. Schiff, M. Bedford, 2020, Nucleic acids research.

FRAP reveals that mobility of oestrogen receptor-α is ligand- and proteasome-dependent

B. O’Malley, Carolyn L. Smith, M. Mancini, 2000, Nature Cell Biology.

Subnuclear Trafficking of Estrogen Receptor-α and Steroid Receptor Coactivator-1

Carolyn L. Smith, M. Mancini, D. Stenoien, 2000 .

Subnuclear partitioning and functional regulation of the Pit‐1 transcription factor

Bing Liu, Z. D. Sharp, M. Mancini, 1999, Journal of cellular biochemistry.

High throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulator

Fabio Stossi, Michael A. Mancini, Michael J. Bolt, 2016, Oncotarget.

FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent.

B. O’Malley, M. Mancini, M. Dutertre, 2001, Nature cell biology.

Ligand-Mediated Assembly and Real-Time Cellular Dynamics of Estrogen Receptor α-Coactivator Complexes in Living Cells

Anne E Carpenter, A. Belmont, Carolyn L. Smith, 2001, Molecular and Cellular Biology.

Regulation of SRC-3 Intercompartmental Dynamics by Estrogen Receptor and Phosphorylation

Adam T. Szafran, M. Mancini, V. Berno, 2007, Molecular and Cellular Biology.

Estrogen-receptor-α exchange and chromatin dynamics are ligand- and domain-dependent

Adam T. Szafran, D. Ingber, Z. D. Sharp, 2006, Journal of Cell Science.

Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone.

N. Weigel, M. Marcelli, M. Mancini, 1999, Human molecular genetics.

Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent.

Adam T. Szafran, D. Ingber, Z. D. Sharp, 2006, Journal of cell science.

Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells

F. Stossi, C. Foulds, M. Mancini, 2019, PloS one.

Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis

Fabio Stossi, Michael A. Mancini, Adam T. Szafran, 2017, PloS one.

Activation of Estrogen Receptor-α by E2 or EGF Induces Temporally Distinct Patterns of Large-Scale Chromatin Modification and mRNA Transcription

M. Mancini, V. Berno, L. Amazit, 2008, PloS one.

Single-Cell Distribution Analysis of AR Levels by High-Throughput Microscopy in Cell Models: Application for Testing Endocrine-Disrupting Chemicals

Adam T. Szafran, F. Stossi, M. Mancini, 2020, SLAS discovery : advancing life sciences R & D.

A Mechanistic High-Content Analysis Assay Using a Chimeric Androgen Receptor That Rapidly Characterizes Androgenic Chemicals

Adam T. Szafran, F. Stossi, F. Claessens, 2020, SLAS discovery : advancing life sciences R & D.

Glowing Genes: A Revolution In Biotechnology

Michael A. Mancini, M. Mancini, Maureen G. Mancini, 2005 .

Quality Control for Single Cell Imaging Analytics Using Endocrine Disruptor-Induced Changes in Estrogen Receptor Expression

Adam T. Szafran, F. Stossi, M. Mancini, 2022, Environmental health perspectives.

High‐Content Screening Identifies Src Family Kinases as Potential Regulators of AR‐V7 Expression and Androgen‐Independent Cell Growth

Michael J. Bolt, Adam T. Szafran, M. Marcelli, 2017, The Prostate.

Activation of Estrogen Receptor-α by E2 or EGF Induces Temporally Distinct Patterns of Large-Scale Chromatin Modification and mRNA Transcription

M. Mancini, V. Berno, L. Amazit, 2008, PloS one.

Gene transcription regulation by ER at the single cell and allele level

F. Stossi, Ragini M. Mistry, M. G. Mancini, 2023, Steroids.