Melissa Lin

发表

Pradigastat disposition in humans: in vivo and in vitro investigations

K. Kulmatycki, C. Meyers, A. Upthagrove, 2017, Xenobiotica; the fate of foreign compounds in biological systems.

Synthesis of 7-(E)-alkenyl-4-amino-3-quinolinecarbonitriles via Pd-mediated Heck, Stille, and Suzuki reactions

D. Berger, M. Dutia, M. B. Floyd, 2009 .

Facile and practical synthesis of a cannabinoid-1 antagonist via regio- and stereoselective ring-opening of an aziridinium ion

M. Girgis, M. Prashad, W. Shieh, 2009 .

Direct oxa-Pictet-Spengler cyclization to the natural (3a,5)-trans-stereochemistry in the syntheses of (+)-7-deoxyfrenolicin B and (+)-7-deoxykalafungin.

J. Bikker, C. Eid, J. Shim, 2009, Journal of Organic Chemistry.

The Scope and Mechanism of Phosphonium-Mediated SNAr Reactions in Heterocyclic Amides and Ureas.

T. Mansour, C. Levins, K. Tabei, 2008 .

The scope and mechanism of phosphonium-mediated S(N)Ar reactions in heterocyclic amides and ureas.

T. Mansour, C. Levins, K. Tabei, 2007, The Journal of organic chemistry.

Use of (1)H NMR to facilitate solubility measurement for drug discovery compounds.

M. Tischler, Melissa Lin, M. Tesconi, 2009, International journal of pharmaceutics.

A multidisciplinary approach to identify a degradation product in a pharmaceutical dosage form.

J. Guan, C. Pan, Melissa Lin, 2011, Journal of Pharmaceutical and Biomedical Analysis.

SAR exploration at the C-3 position of tetrahydro-β-carboline sstr3 antagonists.

Margaret S. Wu, M. Reibarkh, Yun-ping Zhou, 2016, Bioorganic & medicinal chemistry letters.

First Scale-Up: Problems and Resolutions on the Synthesis of WAY-253752, a Novel, Dual-Acting SSRI/5HT1A Antagonist

B. Harrison, G. Stack, M. Young, 2008 .

Discovery of begacestat, a Notch-1-sparing gamma-secretase inhibitor for the treatment of Alzheimer's disease.

T. Comery, K. Fan, B. Harrison, 2008, Journal of medicinal chemistry.

Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans

J. Mangold, O. Simon, H. Einolf, 2016, Drug Metabolism and Disposition.

Protecting group free radical C–H trifluoromethylation of peptides† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00368h

Shane W. Krska, Xiaohong Zhu, S. Krska, 2018, Chemical science.

Protecting group free radical C–H trifluoromethylation of peptides

Shane W. Krska, Xiaohong Zhu, S. Krska, 2018, Chemical science.

Dimethyl sulfoxide mediated elimination reactions in 3-aryl 2,3-dihalopropanoates: scope and mechanistic insights.

T. Mansour, K. Tabei, S. Wacharasindhu, 2007, The Journal of organic chemistry.