R. Coughlin

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Saponin adjuvant induction of ovalbumin-specific CD8+ cytotoxic T lymphocyte responses.

C. Kensil, J. Y. Wu, M. Newman, 1992, Journal of immunology.

Physical properties of defined lipopolysaccharide salts.

A. Haug, E. McGroarty, R. Coughlin, 1983, Biochemistry.

Effect of conjugation methodology, carrier protein, and adjuvants on the immune response to Staphylococcus aureus capsular polysaccharides.

A. Fattom, S. Winston, A. Hawwari, 1995, Vaccine.

Molecular analysis of neutralizing epitopes on outer surface proteins A and B of Borrelia burgdorferi

R. Coughlin, C. Gingrich-Baker, J. Ma, 1995, Infection and immunity.

Characterization of pneumococcal specific antibodies in healthy unvaccinated adults.

D. L. Klein, J. Treanor, G. Carlone, 1998, Vaccine.

Lipopolysaccharide tightly bound to porin monomers and trimers from Escherichia coli K-12

W. Rocque, E. McGroarty, R. Coughlin, 1987, Journal of Bacteriology.

An indirect immunofluorescence assay using a cell culture-derived antigen for detection of antibodies to the agent of human granulocytic ehrlichiosis

J. A. Comer, J. Childs, J. Olson, 1997, Journal of clinical microbiology.

Structure/function studies of QS-21 adjuvant: assessment of triterpene aldehyde and glucuronic acid roles in adjuvant function.

C. Kensil, D. A. Wheeler, J. Y. Wu, 1995, Vaccine.

Safety, efficacy, and immunogenicity of a recombinant Osp subunit canine Lyme disease vaccine.

D. Fish, P. Hine, E. Clough, 1996, Vaccine.

Lyme Vaccine Enhancement

Jianneng Ma, R. Coughlin, D. E. Cox, 1995 .

Serologic and molecular detection of granulocytic ehrlichiosis in Rhode Island

T. Mather, R. Massung, J. Sumner, 1997, Journal of clinical microbiology.

Borrelia burgdorferi Escape Mutants That Survive in the Presence of Antiserum to the OspA Vaccine Are Killed When Complement Is Also Present

M. Philipp, K. Indest, M. Solé, 1998, Infection and Immunity.

Accessory cell requirements for saponin adjuvant-induced class I MHC antigen-restricted cytotoxic T-lymphocytes.

C. Kensil, J. Y. Wu, M. Newman, 1994, Cellular Immunology.

A simple, colorimetric microtiter assay for borreliacidal activity of antisera

Jianneng Ma, R. Coughlin, 1993 .

Adjuvant activity of QS-21 for experimental E. coli 018 polysaccharide vaccines.

A. Fattom, C. Chu, A. White, 1995, Vaccine.

Electron spin resonance probing of lipopolysaccharide domains in the outer membrane of Escherichia coli

A. Haug, E. McGroarty, R. Coughlin, 1983 .

A pH titration study on the ionic bridging within lipopolysaccharide aggregates.

H. Pownall, A. Haug, E. McGroarty, 1985, Biochimica et biophysica acta.

Quantitation of metal cations bound to membranes and extracted lipopolysaccharide of Escherichia coli.

E. McGroarty, R. Coughlin, S. Tonsager, 1983, Biochemistry.

Immunoprotective murine monoclonal antibodies specific for the outer-core polysaccharide and for the O-antigen of Escherichia coli 0111:B4 lipopolysaccharide (LPS).

R. Coughlin, W. C. Bogard, 1987, Journal of immunology.

A purified saponin acts as an adjuvant for a T-independent antigen.

A. White, R. Coughlin, P. Cloutier, 1991, Advances in experimental medicine and biology.

Characterization of canine humoral immune responses to outer surface protein subunit vaccines and to natural infection by Lyme disease spirochetes.

D. Davis, R. Coughlin, P. Bulger, 1995, The Journal of infectious diseases.

Laboratory diagnosis of Clostridium difficile-associated gastrointestinal disease: comparison of a monoclonal antibody enzyme immunoassay for toxins A and B with a monoclonal antibody enzyme immunoassay for toxin A only and two cytotoxicity assays

G. Doern, R. Coughlin, L. Wu, 1992, Journal of Clinical Microbiology.

A thermodynamic and electron paramagnetic resonance study of structural changes in calmodulin induced by aluminum binding.

A. Haug, R. Coughlin, N. Siegel, 1983, Biochemical and biophysical research communications.

Dynamics of maternal IgG antibody decay and HIV-specific antibody synthesis in infants born to seropositive mothers. The NYC Perinatal HIV Transmission Study Group.

N. Shaffer, P. Thomas, G. Schochetman, 1993, AIDS research and human retroviruses.

Thin-layer chromatography of endotoxins, their derivatives and contaminants.

E. Kováts, T. Keler, A. Nowotny, 1988, Journal of chromatography.

Sequence Analysis of the ank Gene of Granulocytic Ehrlichiae

R. Massung, K. Reed, M. Petrovec, 2000, Journal of Clinical Microbiology.

Molecular Cloning and Sequencing of Three Granulocytic Ehrlichia Genes Encoding High-Molecular-Weight Immunoreactive Proteins

K. Munroe, T. Mather, J. Storey, 1998, Infection and Immunity.

Induction of cross-reactive cytotoxic T-lymphocyte responses specific for HIV-1 gp120 using saponin adjuvant (QS-21) supplemented subunit vaccine formulations.

C. Kensil, M. Powell, J. Y. Wu, 1997, Vaccine.

Competence of dogs as reservoirs for Lyme disease spirochetes (Borrelia burgdorferi).

D. Fish, T. Mather, R. Coughlin, 1994, Journal of the American Veterinary Medical Association.

Detection of HIV‐1 IgA by an IgA Capture Enzyme Immunoassay for Early Diagnosis in Infants

G. Schochetman, J. R. George, B. Parekh, 1993 .

Protection of dogs from Lyme disease with a vaccine containing outer surface protein (Osp) A, OspB, and the saponin adjuvant QS21.

C. Pavia, D. Fish, T. Mather, 1995, The Journal of infectious diseases.

Also Present OspA Vaccine Are Killed When Complement Is Survive in the Presence of Antiserum to the Escape Mutants That Borrelia burgdorferi

M. Philipp, K. Indest, M. Solé, 2013 .

Major Antigenic Proteins of the Agent of Human Granulocytic Ehrlichiosis Are Encoded by Members of a Multigene Family

J. Bakken, K. Munroe, J. Storey, 1998, Infection and Immunity.

A cationic electron spin resonance probe used to analyze cation interactions with lipopolysaccharide.

A. Haug, C. R. Caldwell, E. McGroarty, 1981, Biochemical and biophysical research communications.

Immunogenicity and toxicity testing of an experimental HIV-1 vaccine in nonhuman primates.

C. Kensil, J. Y. Wu, M. Newman, 1992, AIDS research and human retroviruses.

Use of electron spin resonance to study Bacillus megaterium spore membranes.

A. Janoff, E. McGroarty, J. Vary, 1979, Biochemical and biophysical research communications.

A program for transition point analysis of experimental data.

D G Brunder, R T Coughlin, E J McGroarty, 1981, Computers in biology and medicine.