Ulf Bredberg

Model-based drug discovery: implementation and impact.

Andrew Hughes, Sandra A G Visser, Malin Aurell, 2013, Drug discovery today.

Optimal Experimental Design for Assessment of Enzyme Kinetics in a Drug Discovery Screening Environment

Erik Sjögren, Joakim Nyberg, Mats O Magnusson, 2011, Drug Metabolism and Disposition.

Early integration of pharmacokinetic and dynamic reasoning is essential for optimal development of lead compounds: strategic considerations.

Hugues Dolgos, Johan Gabrielsson, Ulf Bredberg, 2009, Drug discovery today.

Animal pharmacokinetics of inogatran, a low‐molecular‐weight thrombin inhibitor with potential use as an antithrombotic drug

Ulf Bredberg, Lars Renberg, Ulf G. Eriksson, 1998, Biopharmaceutics & drug disposition.

Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.

Susanne Winiwarter, Ulf Bredberg, Margareta Hammarlund-Udenaes, 2009, Journal of medicinal chemistry.

A new oral anticoagulant: the 50-year challenge

Ingemar Nilsson, Ulf Bredberg, David Gustafsson, 2004, Nature Reviews Drug Discovery.

Improved Measurement of Drug Exposure in the Brain Using Drug-Specific Correction for Residual Blood

Ulf Bredberg, Margareta Hammarlund-Udenaes, Brian Middleton, 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Pharmacokinetics of Methylergometrine in the Rat: Evidence for Enterohepatic Recirculation by a Linked-Rat Model

Ulf Bredberg, U. Bredberg, L. Paalzow, 2004, Pharmaceutical Research.

Pharmacokinetics and pharmacodynamics of ximelagatran, a novel oral direct thrombin inhibitor, in young healthy male subjects

Ulf Bredberg, David Gustafsson, U. Bredberg, 2003, European Journal of Clinical Pharmacology.

Development of a High-Throughput Brain Slice Method for Studying Drug Distribution in the Central Nervous System

Ulf Bredberg, Frederic Ducrozet, Margareta Hammarlund-Udenaes, 2009, Drug Metabolism and Disposition.

Measurement of Unbound Drug Exposure in Brain: Modeling of pH Partitioning Explains Diverging Results between the Brain Slice and Brain Homogenate Methods

Ulf Bredberg, Margareta Hammarlund-Udenaes, Fredrik Bergström, 2011, Drug Metabolism and Disposition.