S. A. Abd El-Karim

发表

New quinoxaline compounds as DPP-4 inhibitors and hypoglycemics: design, synthesis, computational and bio-distribution studies

M. Anwar, T. Sakr, B. M. Essa, 2021, RSC advances.

Discovery of New Coumarin-Based Lead with Potential Anticancer, CDK4 Inhibition and Selective Radiotheranostic Effect: Synthesis, 2D & 3D QSAR, Molecular Dynamics, In Vitro Cytotoxicity, Radioiodination, and Biodistribution Studies

M. Khedr, M. Anwar, W. Zaghary, 2021, Molecules.

Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity.

A. El-Galil E. Amr, E. S. Nossier, M. Abdelhameed, 2021, Bioorganic chemistry.

A Comparative Study of the Anticancer Activity and PARP-1 Inhibiting Effect of Benzofuran–Pyrazole Scaffold and Its Nano-Sized Particles in Human Breast Cancer Cells

A. Amr, M. Al-Omar, M. Anwar, 2019, Molecules.

1,3,4-Triarylpyrazoles Containing 2-Thioxoimidazolidinones and Different Fused Systems: Synthesis and Antimicrobial Activity

E. S. Nossier, S. A. Abd El-Karim, A. G. Shalaby, 2018, Russian Journal of General Chemistry.

Synthesis and 2D-QSAR Study of Active Benzofuran-Based Vasodilators

Aladdin M. Srour, M. Al-Omar, D. Saleh, 2017, Molecules.

Design, Synthesis and Molecular Docking of New Benzimidazole Derivatives of Potential Antimicrobial Activity as DNA Gyrase and Topoisomerase IV Inhibitors

M. Anwar, N. Mahfouz, W. Zaghary, 2021, Egyptian Journal of Chemistry.

Design, synthesis and anticervical cancer activity of new benzofuran-pyrazol-hydrazono- thiazolidin-4-one hybrids as potential EGFR inhibitors and apoptosis inducing agents.

H. Abbas, S. A. Abd El-Karim, 2019, Bioorganic chemistry.

New Quinoxaline-Based Derivatives as PARP-1 Inhibitors: Design, Synthesis, Antiproliferative, and Computational Studies

Khaled M. Elokely, M. Anwar, S. A. Abd El-Karim, 2022, Molecules.

Synthesis and evaluation of anti-inflammatory and analgesic activity of some substituted thiazolyl and thaizolidinonyl tetrahydronapthalene derivatives

M. El-Zahar, S. El-Awdan, M. Haiba, 2014, Medicinal Chemistry Research.

Synthesis and anticancer evaluation of novel isoxazole/pyrazole derivatives

M. M. Said, M. Youns, S. A. Abd El-Karim, 2016, Research on Chemical Intermediates.

New thiazol-hydrazono-coumarin hybrids targeting human cervical cancer cells: Synthesis, CDK2 inhibition, QSAR and molecular docking studies.

Ahmed M. El Kerdawy, S. A. Abd El-Karim, Tamer M. Abdelghany, 2019, Bioorganic chemistry.

Design, synthesis, biological evaluation and molecular docking studies of novel benzofuran-pyrazole derivatives as anticancer agents.

M. Anwar, N. A. Mohamed, T. Nasr, 2015, Bioorganic chemistry.

Synthesis and biological evaluation of new derivatives of thieno-thiazole and dihydrothiazolo-thiazole scaffolds integrated with a pyrazoline nucleus as anticancer and multi-targeting kinase inhibitors

M. Gad-Elkareem, Ismail M M Othman, N. Tashkandi, 2021, RSC advances.

Synthesis, antimicrobial evaluation, and molecular docking studies of new tetrahydrocarbazole derivatives

Walaa S. El‐serwy, N. A. Mohamed, S. A. Abd El-Karim, 2016, Research on Chemical Intermediates.

Synthesis and molecular modeling of new benzimidazoles as glutathione S-transferase inhibitors and anticancer agents.

M. Anwar, Z. M. Nofal, S. A. Abd El-Karim, 2018, Future medicinal chemistry.

Rational design and synthesis of new tetralin-sulfonamide derivatives as potent anti-diabetics and DPP-4 inhibitors: 2D & 3D QSAR, in vivo radiolabeling and bio distribution studies.

M. A. Motaleb, M. Anwar, Manal A. Nael, 2018, Bioorganic chemistry.

Design, synthesis, biological evaluation, QSAR analysis and molecular modelling of new thiazol-benzimidazoles as EGFR inhibitors.

Aladdin M. Srour, S. El-Hallouty, M. Anwar, 2020, Bioorganic & medicinal chemistry.

Kinase Inhibitory Activities and Molecular Docking of a Novel Series of Anticancer Pyrazole Derivatives

S. El-Hallouty, S. A. Abd El-Karim, N. Khalifa, 2018, Molecules.

Rational design, synthesis and 2D-QSAR study of novel vasorelaxant active benzofuran-pyridine hybrids.

Aladdin M. Srour, D. Saleh, W. El-Eraky, 2016, Bioorganic & medicinal chemistry letters.

Novel benzimidazole derivatives as expected anticancer agents.

Aladdin M. Srour, Shalini Sethumadhavan, T. Maher, 2011, Acta poloniae pharmaceutica.

Discovery of novel benzofuran-based derivatives as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis, biological evaluation, molecular docking and 3D-QSAR investigation.

F. F. Mohammed, W. Khalil, H. Aly, 2023, European journal of medicinal chemistry.

Anti-Alzheimer activity of new coumarin-based derivatives targeting acetylcholinesterase inhibition

R. Sandhir, W. Khalil, H. Aly, 2023, RSC advances.

Recent Advances in Structural Optimization of Quinazoline-Based Protein Kinase Inhibitors for Cancer Therapy (2021–Present)

S. A. Abd El-Karim, Sameh H Abdelwahed, Heba T. Abdel-Mohsen, 2024, Molecules.

Benzimidazole-oxindole hybrids: A novel class of selective dual CDK2 and GSK-3β inhibitors of potent anticancer activity.

S. A. Abd El-Karim, Y. Syam, Heba T. Abdel-Mohsen, 2024, Archiv der Pharmazie.

Quinazoline-oxindole hybrids as angiokinase inhibitors and anticancer agents: Design, synthesis, biological evaluation, and molecular docking studies.

S. A. Abd El-Karim, Y. Syam, Heba T. Abdel-Mohsen, 2024, Archiv der Pharmazie.