N. Munagala

发表

Discovery of a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR).

K. Yamaguchi, J. Nuss, J. Woolfrey, 2013, Journal of medicinal chemistry.

Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).

R. Furneaux, V. Schramm, P. Tyler, 2000, Biochemistry.

Identification of small molecule ceramide kinase inhibitors using a homogeneous chemiluminescence high throughput assay.

A. Joly, K. McMillan, Wentao Zhang, 2007, Assay and drug development technologies.

The pivotal role of guanine phosphoribosyltransferase in purine salvage by Giardia lamblia

Ching C. Wang, N. Munagala, C. C. Wang, 2002, Molecular microbiology.

Rational design of novel antimicrobials: blocking purine salvage in a parasitic protozoan.

I. Kuntz, R. Fletterick, J. R. Somoza, 1998, Biochemistry.

Adenosine is the primary precursor of all purine nucleotides in Trichomonas vaginalis.

Ching C. Wang, N. Munagala, 2003, Molecular and biochemical parasitology.

Virtual Screening of Combinatorial Libraries across a Gene Family: in Search of Inhibitors of Giardia lamblia Guanine Phosphoribosyltransferase

Irwin D. Kuntz, Alex M. Aronov, I. Kuntz, 2001, Antimicrobial Agents and Chemotherapy.

Converting the Guanine Phosphoribosyltransferase from Giardia lamblia to a Hypoxanthine-guanine Phosphoribosyltransferase*

Ching C. Wang, N. Munagala, A. Sarver, 2000, The Journal of Biological Chemistry.

Point mutations in the guanine phosphoribosyltransferase from Giardia lamblia modulate pyrophosphate binding and enzyme catalysis.

C. Wang, N. Munagala, J. P. Page, 1999, European journal of biochemistry.

Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47.

C. Wang, N. Munagala, M. Chin, 1998, Biochemistry.

Role of the flexible loop of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus in enzyme catalysis.

C. Wang, V. Basus, V J Basus, 2001, Biochemistry.

Rational design of selective submicromolar inhibitors of Tritrichomonas foetus hypoxanthine-guanine-xanthine phosphoribosyltransferase.

I D Kuntz, A M Aronov, I. Kuntz, 2000, Biochemistry.

Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.

C. Wang, N. Munagala, 1998, Biochemistry.