J. Postelnek

发表

A HIGHLY SELECTIVE INHIBITOR OF IκB KINASE, BMS-345541, AUGMENTS GRAFT SURVIVAL MEDIATED BY SUBOPTIMAL IMMUNOSUPPRESSION IN A MURINE MODEL OF CARDIAC GRAFT REJECTION

K. McIntyre, D. Shuster, Y. Qiu, 2004, Transplantation.

Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase.

Daigen Xu, H. Hilton, J. Demartino, 2013, Arthritis and rheumatism.

Prophylactic administration of abatacept prevents disease and bone destruction in a rat model of collagen-induced arthritis.

L. Killar, B. Krishnan, D. Kukral, 2005, Journal of autoimmunity.

Selective Itk inhibitors block T-cell activation and murine lung inflammation.

A. Doweyko, S. Spergel, R. Moquin, 2004, Biochemistry.

Fit-for-purpose protein biomarker assay validation strategies using hybrid immunocapture-liquid chromatography-tandem-mass spectrometry platform: Quantitative analysis of total soluble cluster of differentiation 73.

Yan J. Zhang, Long Yuan, Yue Zhao, 2020, Analytica chimica acta.

Prophylactic administration of abatacept (CTLA4-Ig; BMS-188667) prevents disease induction and bone destruction in a rat model of collagen-induced arthritis

L. Killar, B. Krishnan, D. Kukral, 2005, Arthritis Research & Therapy.

Novel pyrrolidine heterocycles as CCR1 antagonists.

M. Webb, M. Ohlmeyer, Camelia Chiriac, 2010, Bioorganic & medicinal chemistry letters.

A CCR2/CCR5-dual antagonist, BMS-A, offers a potential novel oral therapy for the treatment of autoimmune disease (92.6)

K. McIntyre, J. Barrish, S. Mandlekar, 2009, Journal of Immunology.

RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents

Daigen Xu, J. Demartino, S. Narula, 2012, Journal of Pharmacology and Experimental Therapeutics.

Novel pyrrolidine ureas as C-C chemokine receptor 1 (CCR1) antagonists.

Ruiyan Liu, Maria L Webb, M. Webb, 2009, Journal of medicinal chemistry.

JPET #187740 RN486 [6-Cyclopropyl-8-fluoro-2-(2-hydroxymethyl-3-{1-methyl-5-[5-(4-methyl- piperazin-1-yl)-pyridin-2-ylamino]-6-oxo-1,6-dihydro-pyridin-3-yl}-phenyl)-2H- isoquinolin-1-one], a Selective Bruton’s Tyrosine Kinase (Btk) Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis

Daigen Xu, J. Demartino, S. Narula, 2011 .

Effects of Elotuzumab on Soluble SLAMF7 Levels in Multiple Myeloma

Michael D. Robbins, J. Sheridan, T. Pazina, 2015 .

Development and Validation of Electrochemiluminescence Assays to Measure Free and Total sSLAMF7 in Human Serum in the Absence and Presence of Elotuzumab

Robert J. Neely, Michael D. Robbins, S. Piccoli, 2016, The AAPS Journal.

Abstract CT180: Preliminary phase 1 profile of BMS-986179, an anti-CD73 antibody, in combination with nivolumab in patients with advanced solid tumors

A. Klippel, H. Burris, L. Siu, 2018, Clinical Trials.

RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents

Daigen Xu, S. Narula, D. Srinivasan, 2012, Journal of Pharmacology and Experimental Therapeutics.