J. Human

发表

Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer's disease.

S. Hitchcock, A. Cheng, Yuan Cheng, 2015, Bioorganic & medicinal chemistry letters.

Structure-Based Design of Potent and Selective CK1γ Inhibitors.

H. Bregman, J. Newcomb, Xin Huang, 2012, ACS medicinal chemistry letters.

(S)‐2‐(Methoxydiphenylmethyl)‐1‐(thiophen‐3‐ylmethyl)pyrrolidine

C. Carlin, C. Ogle, Daniel S Jones, 2003 .

Discovery of dehydro-oxopiperazine acetamides as novel bradykinin B1 receptor antagonists with enhanced in vitro potency.

L. Arik, R. Hungate, Jiawang Zhu, 2012, Bioorganic & medicinal chemistry letters.

Discovery of aryl aminoquinazoline pyridones as potent, selective, and orally efficacious inhibitors of receptor tyrosine kinase c-Kit.

E. Hu, R. Kunz, N. Chen, 2008, Journal of medicinal chemistry.

Discovery of alpha-amidosulfones as potent and selective agonists of CB2: synthesis, SAR, and pharmacokinetic properties.

S. Hitchcock, A. Cheng, R. Fremeau, 2009, Bioorganic & medicinal chemistry letters.

Potent nonpeptide antagonists of the bradykinin B1 receptor: structure-activity relationship studies with novel diaminochroman carboxamides.

Ming Huang, Hong Sun, Eileen Johnson, 2007, Journal of medicinal chemistry.

Chiral lithiothiophenes as non-transferable ligands in organocuprate conjugate addition reactions

C. Ogle, J. Human, 2003 .

Subtle factors are important: radical formation and transmetallation in reactions of butyl cuprates with cyclohexyl iodide.

S. Bertz, C. Ogle, Paul H Seagle, 2005, Organic & biomolecular chemistry.

Lead optimization and modulation of hERG activity in a series of aminooxazoline xanthene β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors.

Xiao Mei Zheng, R. Wahl, A. Cheng, 2014, Journal of medicinal chemistry.

Aryl sulfones as novel bradykinin B1 receptor antagonists for treatment of chronic pain.

L. Arik, R. Hungate, G. Biddlecome, 2008, Bioorganic & medicinal chemistry letters.

Identification of a nonpeptidic and conformationally restricted bradykinin B1 receptor antagonist with anti-inflammatory activity.

L. Arik, E. Laird, V. Viswanadhan, 2007, Journal of medicinal chemistry.