R. Chapman

发表

A novel synthetic 1,3-phenyl bis-thiourea compound targets microtubule polymerization to cause cancer cell death

J. Sarkaria, R. Bram, J. Choi, 2014, Cancer biology & therapy.

Immunomodulatory activity of curcumin: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production in vitro.

S. Dulchavsky, Hao Jiang, G. Divine, 2004, Biochemical pharmacology.

Disparate in vitro and in vivo antileukemic effects of resveratrol, a natural polyphenolic compound found in grapes.

G. Divine, Xiaohua Gao, S. Gautam, 2002, The Journal of nutrition.

Immunomodulatory activity of resveratrol: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production.

Xiaohua Gao, S. Gautam, Yong X. Xu, 2001, Biochemical pharmacology.

Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells.

Hao Jiang, D. Deeb, Xiaohua Gao, 2003, Molecular cancer therapeutics.

TNF-alpha gene therapy with myeloid progenitor cells lacks the toxicities of systemic TNF-alpha therapy.

S. Gautam, K. Pindolia, N. Janakiraman, 1999, Journal of hematotherapy.

IL1α and TNFα Induction of Monocyte Chemoattractant Protein-1 (MCP-1/JE) in Bone Marrow Stromal Cells: The Role of Protein Kinase C (PKC) and Protein Tyrosine Kinase (PTK) Activity.

S. Gautam, K. Pindolia, N. Janakiraman, 1998, Hematology.

In vitro analysis of the antileukemic effect of tumor necrosis factor-alpha gene therapy with myeloid progenitor cells: the role of dendritic cells.

D. Deeb, Xiaohua Gao, S. Gautam, 2003, Journal of experimental therapeutics & oncology.

Antileukemic Activity of TNF-α Therapy with Myeloid Progenitor Cells Against Minimal Leukemia

S. Gautam, K. Pindolia, S. Freytag, 1998 .

Production of monocyte chemotactic protein-1 (MCP-1/JE) by bone marrow stromal cells: Effect on the migration and proliferation of hematopoietic progenitor cells

S. Gautam, N. Janakiraman, R. Chapman, 1999 .

IL-12 gene therapy of leukemia with hematopoietic progenitor cells without the toxicity of systemic IL-12 treatment.

S. Gautam, N. Janakiraman, R. Chapman, 2001, Clinical immunology.

Interleukin-12 (IL-12) gene therapy of leukemia: Immune and anti-leukemic effects of IL-12-transduced hematopoietic progenitor cells

S. Gautam, Yong X. Xu, N. Janakiraman, 2000, Cancer Gene Therapy.

Nonselective inhibition of proliferation of transformed and nontransformed cells by the anticancer agent curcumin (diferuloylmethane).

S. Gautam, K. Pindolia, N. Janakiraman, 1998, Biochemical pharmacology.

The multiple phosphorylation of the microtubule-associated protein MAP2 controls the MAP2:tubulin interaction.

K. Islam, R. Burns, R. Chapman, 1984, European journal of biochemistry.

Substrate-targeting γ-secretase modulators

M. Wolfe, D. Walsh, T. Golde, 2008, Nature.

Ras controls tumor necrosis factor receptor-associated factor (TRAF)6-dependent induction of nuclear factor-kappa b. Selective regulation through receptor signaling components.

F. Carlotti, E. Kiss-Toth, E. Qwarnstrom, 2001, The Journal of biological chemistry.

Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-KB through suppression of IKBA phosphorylation

S. Dulchavsky, G. Divine, Hao Jiang, 2004 .

Activation of nuclear factor kappaB in single living cells. Dependence of nuclear translocation and anti-apoptotic function on EGFPRELA concentration.

F. Carlotti, S. Dower, E. Qwarnstrom, 1999, The Journal of biological chemistry.

Curcumin inhibits IL1 alpha and TNF-alpha induction of AP-1 and NF-kB DNA-binding activity in bone marrow stromal cells.

S. Gautam, K. Pindolia, N. Janakiraman, 1997, Hematopathology and molecular hematology.

Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation.

S. Dulchavsky, G. Divine, Hao Jiang, 2004, Molecular cancer therapeutics.

Immunomodulatory activity of resveratrol: discrepant in vitro and in vivo immunological effects.

Hao Jiang, George Divine, G. Divine, 2003, Biochemical pharmacology.

Induction of chemokine mRNA in bone marrow stromal cells: modulation by TGF-beta 1 and IL-4.

S. Gautam, K. Pindolia, N. Janakiraman, 1995, Experimental hematology.

Resveratrol selectively inhibits leukemia cells: a prospective agent for ex vivo bone marrow purging

S. Gautam, Yong X. Xu, N. Janakiraman, 2000, Bone Marrow Transplantation.