M. Sills

发表

Application of Scintillating Microtiter Plates to Measure Phosphopeptide Interactions with the GRB2-SH2 Binding Domain

L. Wennogle, K. Lipson, A. Braunwalder, 1996 .

[3H]2-phenylaminoadenosine ([3H]CV 1808) labels a novel adenosine receptor in rat brain.

S. Hurt, L. Cornfield, M. Sills, 1992, The Journal of pharmacology and experimental therapeutics.

Iron Deficiency Alters Discrete Proteins in Rat Caudate Nucleus and Nucleus Accumbens

D. Jacobowitz, M. Youdim, M. Youdim, 1986, Journal of neurochemistry.

High affinity interleukin-6 binding sites in bovine hypothalamus.

L. Cornfield, M. Sills, 1991, European journal of pharmacology.

CGS 21680 : a potent selective adenosine A2 receptor agonist

J. Balwierczak, R. Webb, M. Sills, 1992 .

Species differences in high‐affinity adenosine A2 binding sites in striatal membranes from mammalian brain

B. Weeks, M. Williams, M. Jarvis, 1988 .

Biochemical characterization of the antagonist actions of the xanthines, PACPX (1,3-dipropyl-8(2-amino-4-chloro)phenylxanthine) and 8-PT (8-phenyltheophylline) at adenosine A1 and A2 receptors in rat brain tissue.

M. Williams, M. Jarvis, J. Ferkany, 1987, Biochemical pharmacology.

New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis.

G. Martiny-Baron, K. Altmann, R. Cozens, 2000, Journal of medicinal chemistry.

Cardiovascular effects produced by microinjection of calcitonin gene-related peptide into the rat central amygdaloid nucleus

D. Jacobowitz, K. Nguyen, M. Sills, 1986, Peptides.

Comparison of antagonist and agonist binding to the leukotriene B4 receptor intact human polymorphonuclear neutrophils (PMN).

M. Morrissey, M. Jarvis, M. Sills, 1992, The Journal of pharmacology and experimental therapeutics.

Novel C5a receptor antagonists regulate neutrophil functions in vitro and in vivo.

W. Boyar, L. Wennogle, J. van Oostrum, 1998, Journal of immunology.

Characterization of the binding of Bolton-Hunter labeled [125I]C5a to human neutrophil, monocyte and U-937 cell membranes.

B. Seligmann, L. Wennogle, A. Braunwalder, 1992, Molecular immunology.

In vitro screens and functional assays to assess receptor pharmacology

M. Sills, 1994 .

Increases in heart rate and blood pressure produced by microinjections of atrial natriuretic factor into the AV3V region of rat brain

D. Jacobowitz, K. Nguyen, M. Sills, 1985, Peptides.

Determination of selective and nonselective compounds for the 5-HT 1A and 5-HT 1B receptor subtypes in rat frontal cortex.

A. Frazer, B. Wolfe, M. Sills, 1984, The Journal of pharmacology and experimental therapeutics.

Novel spirodihydrobenzofuranlactams as antagonists of endothelin and as inhibitors of HIV-1 protease produced by Stachybotrys Sp. I. Fermentation, isolation and biological activity.

H. H. Peter, F. Petersen, J. Roesel, 1996, The Journal of antibiotics.

Identification of a High-Affinity Anti-Phosphoserine Antibody for the Development of a Homogeneous Fluorescence Polarization Assay of Protein Kinase C

J. J. Wu, Q. Pham, M. Sills, 2000, Journal of biomolecular screening.

Interaction of the D1 receptor antagonist SCH 23390 with the central 5-HT system: radioligand binding studies, measurements of biochemical parameters and effects on L-5-HTP syndrome.

M. Williams, S. Bischoff, M. Heinrich, 1988, Journal of receptor research.

Characterization of the binding of a novel nonxanthine adenosine antagonist radioligand, [3H]CGS 15943, to multiple affinity states of the adenosine A1 receptor in the rat cortex.

M. Williams, M. Jarvis, M. Sills, 1991, Molecular pharmacology.

The novel anticonvulsant MK-801 interacts with central phencyclidine recognition sites in rat brain.

M. Williams, P. Loo, A. Braunwalder, 1987, European journal of pharmacology.

Interaction of L-glutamate and magnesium with phencyclidine recognition sites in rat brain: evidence for multiple affinity states of the phencyclidine/N-methyl-D-aspartate receptor complex.

M. Williams, J. Lehmann, P. Loo, 1987, Molecular pharmacology.

Synthesis, opioid receptor binding profile, and antinociceptive activity of 1-azaspiro[4.5]decan-10-yl amides.

M. Williams, R. Fujimoto, J. Simke, 1989, Journal of medicinal chemistry.

Microxine, a new cdc2 kinase inhibitor from the Australian marine sponge Microxina species.

A. Wright, J. Hooper, K. Killday, 2001, Journal of natural products.

[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain.

M. Williams, M. Jarvis, M. Sills, 1989, The Journal of pharmacology and experimental therapeutics.

Isolation and structure elucidation of perthamide B, a novel peptide from the sponge Theonella sp.

S. Pomponi, A. Wright, N. Gulavita, 1994 .

Eryloside E from an atlantic sponge Erylus goffrilleri

M. Kelly-Borges, A. Wright, R. Longley, 1994 .

Characterization of rat lung endothelin receptor subtypes which are coupled to phosphoinositide hydrolysis.

C. Cioffi, M. Sills, R. H. Jackson, 1992, The Journal of pharmacology and experimental therapeutics.

Isolation and structure elucidation of 34-sulfatobastadin 13, an inhibitor of the endothelin A receptor, from a marine sponge of the genus Ianthella.

M. Kelly-Borges, S. Pomponi, A. Wright, 1993, Journal of natural products.

Benzofuro[2,3-c]pyridin-6-ols: synthesis, affinity for opioid-receptor subtypes, and antinociceptive activity.

M. Williams, J. Simke, M. Sills, 1989, Journal of medicinal chemistry.

Further Comparison of Primary Hit Identification by Different Assay Technologies and Effects of Assay Measurement Variability

Ji-Hu Zhang, Xiang Wu, Xiang Wu, 2005, Journal of biomolecular screening.

Comparison of Assay Technologies for a Tyrosine Kinase Assay Generates Different Results in High Throughput Screening

Robert Schweitzer, Jinzi J Wu, Xiang Wu, 2002, Journal of biomolecular screening.

Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1, receptor subtypes in the rat brain

M. Williams, P. Waldmeier, S. Bischoff, 1988, Naunyn-Schmiedeberg's Archives of Pharmacology.

Biochemical and pharmacological characterization of the putative dopamine autoreceptor agonist benzopyranopyridine, CGS 15873A

R. A. Lovell, J. Liebman, M. Williams, 1989 .

Bis(sulfato)-cyclosiphonodictyol A, a new disulfated sesquiterpene-hydroquinone from a deep water collection of the Marine sponge Siphonodictyon coralliphagum.

A. Wright, K. Killday, M. Sills, 1995, Journal of natural products.

The discovery and characterization of an interleukin 6 cytokine family antagonist protein from a marine sponge, Callyspongia sp.

S. Pomponi, L. Wennogle, A. Wright, 2001, Advances in experimental medicine and biology.

Characterization of an Interleukin 6 Cytokine Family Antagonist Protein from a Marine Sponge, Callyspongia sp.(*)

S. Pomponi, A. Wright, J. Peppard, 1996, The Journal of Biological Chemistry.

Autoradiographic distribution of 125I-galanin binding sites in the rat central nervous system

D. Jacobowitz, G. Skofitsch, M. Sills, 1986, Peptides.

Comparison of Assay Technologies for a Nuclear Receptor Assay Screen Reveals Differences in the Sets of Identified Functional Antagonists

J Fraser Glickman, B. Bowen, Xiang Wu, 2003, Journal of biomolecular screening.

Effect of chronic treatment with clorgyline on the relative concentration of specific proteins in the hippocampus and parietal cortex of the rat

D. Jacobowitz, R. Cohen, M. Sills, 1986, Neuropharmacology.

[3H]CGP 39653: a new N-methyl-D-aspartate antagonist radioligand with low nanomolar affinity in rat brain.

G. Fagg, M. Williams, M. Pozza, 1991, European journal of pharmacology.

Multiple states of the 5-hydroxytryptamine1 receptor as indicated by the effects of GTP on [3H]5-hydroxytryptamine binding in rat frontal cortex.

A. Frazer, B. Wolfe, M. Sills, 1984, Molecular pharmacology.

Tricyclic antidepressants and dextromethorphan bind with higher affinity to the phencyclidine receptor in the absence of magnesium and L-glutamate.

P. Loo, M. Sills, 1989, Molecular pharmacology.

Future considerations in HTS: the acute effect of chronic dilemmas

Matthew A. Sills, M. Sills, 1998 .

The pharmacophore of the human C5a anaphylatoxin

W. Boyar, B. Seligmann, A. Braunwalder, 1994, Protein science : a publication of the Protein Society.

Central muscarinic cholinergic antagonists block wet-dog shakes produced by the TRH analog MK-771 in the rat

D. Jacobowitz, T. Sunderland, A. Mellow, 1988, Brain Research.

Measurement of the protein tyrosine kinase activity of c-src using time-resolved fluorometry of europium chelates.

K. Lipson, A. Braunwalder, M. Sills, 1996, Analytical biochemistry.

A solid-phase assay for the determination of protein tyrosine kinase activity of c-src using scintillating microtitration plates.

K. Lipson, M. Missbach, M. Sills, 1996, Analytical biochemistry.

Chronic administration of desipramine or nialamide decreases wet-dog shakes in rats produced by the TRH-analog MK-771

D. Jacobowitz, M. Sills, 1987, Brain Research.

Alterations in monoamine-containing neuronal function due to administration of antidepressants repeatedly to rats.

I. Lucki, A. Frazer, M. Sills, 2009, Acta pharmacologica et toxicologica.

Development of selective tolerance to the serotonin behavioral syndrome and suppression of locomotor activity after repeated administration of either 5-MeODMT or mCPP.

I. Lucki, A. Frazer, M. Sills, 1985, Life sciences.

A Comparison of ALPHAScreen, TR-FRET, and TRF as Assay Methods for FXR Nuclear Receptors

J Fraser Glickman, B. Bowen, Xiang Wu, 2002, Journal of biomolecular screening.

2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors.

David J Diller, Maria L Webb, M. Webb, 2009, Bioorganic & medicinal chemistry letters.

Characterization of the binding of [3H]‐CGS 19755: a novel N‐methyl‐d‐aspartate antagonist with nanomolar affinity in rat brain

M. Williams, D. Murphy, S. Hurt, 1988, British journal of pharmacology.

The NMDA antagonists, CPP and CGS 19755, lack affinity for central benzodiazepine receptors.

M. Williams, P. Loo, M. Sills, 1988, European journal of pharmacology.

Isolation and Structure Elucidation of Perthamide B, a Novel Peptide from the Sponge Theonella sp.

S. Pomponi, A. Wright, N. Gulavita, 1995 .

Aplysillin A, a thrombin receptor antagonist from the marine sponge Aplysina fistularis fulva.

S. Pomponi, A. Wright, N. Gulavita, 1995, Journal of Natural Products.

Propranolol and methylatropine antagonize the cardiovascular effects produced by microinjection of the TRH analog MK-771 into the preoptic suprachiasmatic nucleus

D. Jacobowitz, M. Sills, 1988, Peptides.

Development of tolerance to the antihypertensive effects of highly selective adenosine A2a agonists upon chronic administration.

R. Webb, J. Peppard, M. Sills, 1993, The Journal of pharmacology and experimental therapeutics.

The N-methyl-D-aspartate receptor complex.

M. Jarvis, D. Murphy, P. Loo, 1988, Journal of receptor research.