A. Peden

发表

Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes.

M. Houslay, S. Mackenzie, G. Bolger, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Prion Diseases of Humans

J. Ironside, D. Ritchie, A. Peden, 2015 .

Effects of human PrPSc type and PRNP genotype in an in-vitro conversion assay

C. Prowse, M. Turner, J. Ironside, 2008, Neuroreport.

Short Communication Abnormal prion protein in the pituitary in sporadic and variant Creutzfeldt-Jakob disease

J. Ironside, A. Dean, M. Head, 2007 .

Abnormal prion protein in the pituitary in sporadic and variant Creutzfeldt-Jakob disease.

J. Ironside, A. Dean, M. Head, 2007, The Journal of general virology.

Review: pathology of variant Creutzfeldt-Jakob disease.

J. Ironside, A. Peden, 2004, Folia neuropathologica.

UK Iatrogenic Creutzfeldt–Jakob disease: investigating human prion transmission across genotypic barriers using human tissue-based and molecular approaches

J. Ironside, M. Head, M. Barria, 2016, Acta Neuropathologica.

Detection and localization of PrPSc in the skeletal muscle of patients with variant, iatrogenic, and sporadic forms of Creutzfeldt-Jakob disease.

J. Ironside, M. Head, D. Ritchie, 2006, The American journal of pathology.

Intracellular compartmentalization of PDE4 cyclic AMP-specific phosphodiesterases.

M. Houslay, S. Mackenzie, E. Huston, 1998, Methods.

Study protocol for enhanced CJD surveillance in the 65+ years population group in Scotland: an observational neuropathological screening study of banked brain tissue donations for evidence of prion disease

A. Molesworth, L. Kanguru, D. Ritchie, 2019, BMJ Open.

Risk of Transmission of Creutzfeldt–Jakob Disease by Blood Transfusion

J. Ironside, M. Head, A. Peden, 2013 .

Human platelets as a substrate source for the in vitro amplification of the abnormal prion protein (PrPSc) associated with variant Creutzfeldt‐Jakob disease

C. Prowse, M. Turner, J. Ironside, 2008, Transfusion.

Disease‐associated prion protein is not detectable in human systemic amyloid deposits

M. Pepys, P. Hawkins, G. Tennent, 2007, The Journal of pathology.

Neuropathology of Neurodegenerative Diseases: Human prion diseases

J. Ironside, M. Head, D. Ritchie, 2000 .

Epitope mapping of the protease resistant products of RT-QuIC does not allow the discrimination of sCJD subtypes

A. Green, M. Barria, Marcelo A Barria, 2019, PloS one.

Variably Protease-Sensitive Prionopathy, a Unique Prion Variant with Inefficient Transmission Properties

J. Ironside, J. Manson, D. Ritchie, 2014, Emerging infectious diseases.

Distinct Stability States of Disease-Associated Human Prion Protein Identiﬁed by Conformation-Dependent Immunoassay (cid:1)

J. Ironside, M. Head, A. Gröner, 2010 .

Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversion.

B. Caughey, J. Ironside, A. Green, 2012, The Journal of general virology.

Abnormal prion protein in the retina of the most commonly occurring subtype of sporadic Creutzfeldt-Jakob disease

J. Ironside, M. Head, D. Ritchie, 2005, British Journal of Ophthalmology.

Variant CJD infection in the spleen of a neurologically asymptomatic UK adult patient with haemophilia

S. Love, S. Cousens, J. Ironside, 2010, Haemophilia : the official journal of the World Federation of Hemophilia.

Edinburgh Research Explorer Rapidly progressive dementia with thalamic degeneration and peculiar cortical prion protein immunoreactivity, but absence of proteinase K resistant PrP

R. Katzenschlager, E. Hametner, J. Ironside, 2013 .

Preclinical variant CJD after blood transfusion in a PRNP codon 129 heterozygous patient

Mark Head, James W. Ironside, J. Ironside, 2004 .

Asymptomatic vCJD infection detected at autopsy in a UK haemophilic patient

J. Ironside, M. Head, H. Ward, 2010 .

Attenuation of the Activity of the cAMP-specific Phosphodiesterase PDE4A5 by Interaction with the Immunophilin XAP2*

G. Baillie, M. Houslay, David G. McEwan, 2003, Journal of Biological Chemistry.

Distinct Stability States of Disease-Associated Human Prion Protein Identified by Conformation-Dependent Immunoassay

J. Ironside, M. Head, A. Gröner, 2010, Journal of Virology.

Advances in the development of a screening test for variant Creutzfeldt-Jakob disease.

M. Turner, J. Ironside, I. Macgregor, 2008, Expert opinion on medical diagnostics.

The intracellular targeting and regulation of PDE4 cyclic AMP-specific phosphodiesterase enzymes

A. Peden, 2000 .

A nonphosphorylated 14-3-3 binding motif on exoenzyme S that is functional in vivo.

A. Aitken, R. Palmer, B. Hallberg, 2002, European journal of biochemistry.

Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient

M. Head, Alexander H Peden, Mark W Head, 2004, The Lancet.

BCR kinase phosphorylates 14‐3‐3 Tau on residue 233

A. Aitken, S. Mackie, S. Clokie, 2005, The FEBS journal.

The prion protein protease sensitivity, stability and seeding activity in variably protease sensitive prionopathy brain tissue suggests molecular overlaps with sporadic Creutzfeldt-Jakob disease

J. Ironside, M. Head, M. Barria, 2014, Acta neuropathologica communications.

Rapidly progressive dementia with thalamic degeneration and peculiar cortical prion protein immunoreactivity, but absence of proteinase K resistant PrP: a new disease entity?

S. Weis, H. Budka, R. Katzenschlager, 2013, Acta neuropathologica communications.

Understanding Intra-Species and Inter-Species Prion Conversion and Zoonotic Potential Using Protein Misfolding Cyclic Amplification

M. Barria, Marcelo A Barria, A. Peden, 2021, Frontiers in Aging Neuroscience.

Amyloid-β accumulation in the CNS in human growth hormone recipients in the UK

Rosemary J. Jackson, M. Keogh, P. Chinnery, 2017, Acta Neuropathologica.

Real time quaking‐induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt–Jakob disease

Mary Andrews, B. Caughey, A. Green, 2012, Annals of neurology.

Variant CJD: Reflections a Quarter of a Century on

M. Barria, D. Ritchie, Marcelo A Barria, 2021, Pathogens.

RT-QuIC analysis of cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease: a potential new diagnostic test

Bob Will, Mark Head, Mary Andrews, 2012 .

Prion seeding activity in cerebrospinal fluid from sporadic Creutzfeldt-Jakob disease patients using real-time QuIC analysis: a potential new diagnostic test?

B. Caughey, A. Green, N. E. Appleford, 2011 .

Specificity of 14-3-3 isoform dimer interactions and phosphorylation.

A Aitken, H. Baxter, A. Aitken, 2001, Biochemical Society transactions.

TAPAS-1, a Novel Microdomain within the Unique N-terminal Region of the PDE4A1 cAMP-specific Phosphodiesterase That Allows Rapid, Ca2+-triggered Membrane Association with Selectivity for Interaction with Phosphatidic Acid*

Jim Warwicker, Michael J O Wakelam, J. Warwicker, 2002, The Journal of Biological Chemistry.

Comparison of the in vitro seeding activity of UK iatrogenic and sporadic Creutzfeldt-Jakob disease subtypes by real time quaking induced conversion

J. Ironside, M. Head, A. Peden, 2016 .

Risks of transmission of variant Creutzfeldt-Jakob disease by blood transfusion.

J. Ironside, D. Ritchie, A. Peden, 2006, Folia neuropathologica.

Molecular pathology in neurodegenerative diseases.

J. Ironside, A. Peden, 2012, Current drug targets.

The application of in vitro cell-free conversion systems to human prion diseases

J. Ironside, M. Head, A. Peden, 2010, Acta Neuropathologica.

41313 Proteins in Cell Regulation

H. Baxter, A. Aitken, K. Mitchell, 2002 .

Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient.

J. Bell, J. Ironside, M. Head, 2004, Lancet.

Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient.

J. Bell, J. Ironside, M. Head, 2004, Lancet.

In vitro amplification and detection of variant Creutzfeldt–Jakob disease PrPSc

C. Prowse, J. Ironside, J. Manson, 2007, The Journal of pathology.

Iatrogenic Creutzfeldt – Jakob disease : investigating human prion transmission across genotypic barriers using human tissue ‐ based and molecular approaches

J. Ironside, M. Head, D. Ritchie, 2016 .

Edinburgh Research Explorer Understanding Intra-Species and Inter-Species Prion Conversion and Zoonotic Potential Using Protein Misfolding Cyclic Amplification

A. Peden, Suzanne Suleiman, Marcelo A. Barria, 2022 .

UK Iatrogenic Creutzfeldt–Jakob disease: investigating human prion transmission across genotypic barriers using human tissue-based and molecular approaches

A. Peden, H. Yull, James R M Kirkpatrick, 2016, Acta Neuropathologica.