Jun Yan

发表

The design, synthesis and anti-tumor mechanism study of new androgen receptor degrader.

Yu Ke, Hang Xie, Hong-min Liu, 2020, European journal of medicinal chemistry.

The discovery of a potent and selective third-generation EGFR kinase inhibitor as a therapy for EGFR L858R/T790M double mutant non-small cell lung cancer.

A. Chan, Jinhui Hu, Tingting Pan, 2019, European journal of medicinal chemistry.

Synthesis, biological evaluation and mechanism study of a class of cyclic combretastatin A-4 analogues as novel antitumour agents

Jinhui Hu, Xingshu Li, Ling Huang, 2015 .

Synthesis, biological evaluation and mechanism study of a class of benzylideneindanone derivatives as novel anticancer agents

Jinhui Hu, Xingshu Li, Ling Huang, 2015 .

Synthesis, biological evaluation and mechanism study of chalcone analogues as novel anti-cancer agents

Jinhui Hu, Xingshu Li, Ling Huang, 2015 .

The convenient aqueous synthesis and biological evaluation of ortho-(3,4,5-trimethoxybenzoyl)-acetanilides as novel anti-cancer agents

Xingshu Li, Ling Huang, F. Mao, 2014 .

Design, synthesis, and evaluation of multitarget-directed ligands against Alzheimer's disease based on the fusion of donepezil and curcumin.

Jinhui Hu, Xingshu Li, Anqiu Liu, 2017, Bioorganic & medicinal chemistry.

Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo.

Jinhui Hu, Xingshu Li, Ling Huang, 2016, Journal of medicinal chemistry.

Discovery of Novel Quinazoline-based KRAS G12C Inhibitors as Potential Anticancer Agents

Jingxuan Chen, Ruiyao Mai, Huiting Zhao, 2022, Bioorganic & Medicinal Chemistry.

A dual-channel fluorescent probe for monitoring pH changes in lysosomes during autophagy

Weiying Lin, Ling Huang, Jun Yan, 2021, New Journal of Chemistry.

A novel series of tacrine-selegiline hybrids with cholinesterase and monoamine oxidase inhibition activities for the treatment of Alzheimer's disease.

Xingshu Li, Ling Huang, Z. Du, 2013, European journal of medicinal chemistry.

Synthesis and in vitro biological evaluation of novel derivatives of Flexicaulin A condensation with amino acid trifluoroacetate.

Yu Ke, Hang Xie, Hong-min Liu, 2019, European journal of medicinal chemistry.

Design, Synthesis, and Biological Evaluation of Novel Selenium-Containing Isocombretastatins and Phenstatins as Antitumor Agents.

B. An, Xingshu Li, Ling Huang, 2017, Journal of medicinal chemistry.

Synthesis and evaluation of multi-target-directed ligands against Alzheimer's disease based on the fusion of donepezil and ebselen.

Yang Sun, Hai-Bin Luo, Xingshu Li, 2013, Journal of medicinal chemistry.

Design, synthesis, and evaluation of multitarget-directed resveratrol derivatives for the treatment of Alzheimer's disease.

Hai-bin Luo, Xingshu Li, Ling Huang, 2013, Journal of medicinal chemistry.

Design, Synthesis, and Evaluation of New Mesenchymal–Epithelial Transition Factor (c-Met) Kinase Inhibitors with Dual Chiral Centers

Ming Yan, Jinhui Hu, Xingshu Li, 2022, Molecules.

Design, synthesis, and biological evaluation of benzoselenazole-stilbene hybrids as multi-target-directed anti-cancer agents.

Xingshu Li, Ling Huang, F. Mao, 2015, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of cyclic-indole derivatives as anti-tumor agents via the inhibition of tubulin polymerization.

Li Huang, Jinhui Hu, B. An, 2017, European journal of medicinal chemistry.

The synthesis and evaluation of new benzophenone derivatives as tubulin polymerization inhibitors

B. An, Xingshu Li, Ling Huang, 2016 .

The synthesis and evaluation of new butadiene derivatives as tubulin polymerization inhibitors.

B. An, Xingshu Li, Ling Huang, 2017, Bioorganic & medicinal chemistry.

A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.

Jinhui Hu, Xingshu Li, Ling Huang, 2015, Biochemical pharmacology.

Discovery of novel PDE9 inhibitors capable of inhibiting Aβ aggregation as potential candidates for the treatment of Alzheimer’s disease

Hai-Bin Luo, Yinuo Wu, Hai-bin Luo, 2016, Scientific Reports.

Synthesis, biological evaluation, and molecular modeling of glycyrrhizin derivatives as potent high-mobility group box-1 inhibitors with anti-heart-failure activity in vivo.

Zhuo-wei Hu, H. Lv, Yadan Wang, 2013, Journal of medicinal chemistry.

New multi-target-directed small molecules against Alzheimer's disease: a combination of resveratrol and clioquinol.

Xingshu Li, Ling Huang, F. Mao, 2014, Organic & biomolecular chemistry.

The development of a highly selective fluorescent probe for the rapid detection of HClO in living cells and zebrafish

Weiying Lin, Ling Huang, Jun Yan, 2021 .

Discovery of a Novel Stilbene Derivative as a Microtubule Targeting Agent Capable of Inducing Cell Ferroptosis.

Jingwei Zhou, Xingshu Li, Weiwei Zhang, 2022, Journal of medicinal chemistry.

Synthesis, in vitro and in vivo evaluation of new hybrids of millepachine and phenstatin as potent tubulin polymerization inhibitors.

B. An, Xingshu Li, Ling Huang, 2017, Organic & biomolecular chemistry.

Synthesis and biological evaluation of berberine-thiophenyl hybrids as multi-functional agents: Inhibition of acetylcholinesterase, butyrylcholinesterase, and Aβ aggregation and antioxidant activity.

Xingshu Li, Ling Huang, Jun Yan, 2013, Bioorganic & medicinal chemistry.